Synthesis,and Antimycobacterial and Cytotoxic Evaluation of Certain Fluoroquinolone Derivatives

Certain 1‐ethyl‐ and 1‐aryl‐6‐fluoro‐1,4‐dihydroquinol‐4‐one derivatives were synthesized and evaluated for antimycobacterial and cytotoxic activities. Preliminary results indicated that, for 1‐aryl‐6‐fluoroquinolones, both 7‐(piperazin‐1‐yl)‐ and 7‐(4‐methylpiperazin‐1‐yl) derivatives, 9b and 11a , are able to completely inhibit the growth of M. tuberculosis at a concentration of 6.25 μg/ml, while the 7‐[4‐(2‐oxo‐2‐phenylethyl)piperazin‐1‐yl] derivative 13 exhibits only 31% growth inhibition at the same concentration. For 1‐ethyl‐6‐fluoroquinolones, both 7‐[4‐(2‐oxopropyl)piperazin‐1‐yl]‐ and 7‐[4‐(2‐oxo‐2‐phenylethyl)piperazin‐1‐yl]‐derivatives, 2a and 2b , respectively, show complete inhibition, while their 2‐iminoethyl and substituted phenyl counterparts 3a and 2c are less active. In addition, the 6,8‐difluoro derivative was a more‐favorable inhibitor than its 6‐fluoro counterpart ( 2b vs. 2d ). These results deserve full attention especially because 2a, 2b, 9b , and 11a are non‐cytotoxic at a concentration of 100 μM . Furthermore, compound 9b proved to be a potent anti‐TB agent with selective index (SI)>40 and an EC₉₀ value of 5.75 μg/ml.     

Single Production of Charged Top-Pions at High Energy Linear e+e- Colliders

The dominant decay modes of charged top-pions (π±t ) are tb or ~b. We consider the single production ofcharged top-pions in association with a top quark via e+ e- annihilation and calculate the production cross section of theprocesses e+ e- → t-bπ+ (tb-π-) at the leading order. We find that it can reach 1.2 fb with reasonable parameter values.The charged top-pions may be detected via the channel tbπ± in the future high energy e+ e- colliders.     

光学系统光阑应用的实例

介绍了一种光学组合系统，通过构造光学系统虚拟的视场光阑实现人眼屈光度测量，它是光学系统光阑应用的生动实例.     

基于免疫算法的Hopfield神经网络多用户检测器

提出的基于免疫算法的Hopfield神经网络多用户检测器，将扰乱的Hopfield神经网络多用户检测器的输出作为免疫算法的初始种群，利用了免疫算法的全局收敛的特点，从而克服了Hopfield易收敛到局部能量最小点的缺点。理论分析和仿真结果表明：该检测器具有良好的抗多址干扰和抗远近效应的能力。     

ATM与帧中继互连技术

ＡＴＭ技术是ＩＴＵ－Ｔ推荐的Ｂ－ＩＳＤＮ交换技术，而帧中继在提供广域网业务方面很成功。因此，在ＡＴＭ发展的初期不可避免地会与帧中继技术并存。本文阐述了ＡＴＭ与帧中继网络互加和业务互连的相关技术及其存在的问题。     

无创血压测量方法的研究

简要介绍了血压测量技术的发展概况，重点介绍了示渡法工作原理、判别准则和方法比较，对测量算法进行了详细介绍，并结合MOTORLA公司的MC68HC908LJ12简要介绍了示波法电子血压计实现方法，最后就影响血压测量的主要因素进行了简要分析。     

A full-duplex radio-over-fiber system based on optical carrier suppression and reuse

We have experimentally demonstrated a full-duplex radio-over-fiber system using a single light source at central station (CS). Optical carrier suppression modulation scheme was employed to generate 40-GHz optical millimeter wave and up-convert the baseband signal simultaneously at CS for downlink transmission while the same optical carrier was reused at base station for uplink connection. The bidirectional full-duplex 2.5-Gb/s data was successfully transmitted over 40-km standard single-mode fiber (SMF-28) for both upstream and downstream channels with less than 2-dB power penalty. This system shows simple cost-efficient configuration and good performance over long-distance delivery.     

高帧速摄像器

本文介绍了高帧速摄像器的设计、制造、工作和性能。该高帧速有３６０×３６０像素、摄像速度高达５×１０５帧／秒，该摄像器读出电路类似于帧转移ＣＣＤ，由四部分组成     

功率GaAs MESFET的热阻测试

阐述了功率ＧａＡｓＭＥＳＦＥＴ器件热阻测试中温敏参数ＶＧＳＦ和测试电流Ｉｍ的选取，给出了１～５Ｗ器件典型温敏参数的温度测试系数Ｍ与测试电流Ｉｍ的关系。讨论了测试延迟时间ｔｍｄ对△ＶＧＳＦ测量值的影响和三种校正方法。     

ASYMPTOTIC APPROXIMATION METHOD AND ITS CONVERGENCE ON SEMI-INFINITE PROGRAMMING

The aim of this article is to discuss an asymptotic approximation model and its convergence for the minimax semi-infinite programming problem. An asymptotic surrogate constraints method for the minimax semi-infinite programming problem is presented by making use of two general discrete approximation methods. Simultaneously, the consistence and the epi-convergence of the asymptotic approximation problem are discussed.