纳米金-银加强法对大鼠和猴脊髓后角内P物质定位的实验研究

包埋前纳米金－银加强法已较广泛地应用于对神经递质和受体的超微定位研究，被证明是一种敏感和高分辨率的方法。Ｐ物质是在脊髓后角内十分丰富的一种神经肽，我们应用这一技术研究Ｐ物质的定位时，发现当大致密芯泡的泡芯密度高时，其内的神经肽无法被纳米金－银颗粒标记，只在泡膜附近有金－银颗粒标记，这一现象在猴的脊髓后角神经终末中尤为明显，虽然这个缺点不影响研究含这种神经肽的神经终末与其它结构的关系，但据此结果来阐     

Generation, measurement of 1.5ps ultrafast electrical pulse and its propagation on the microstrip line

We have designed a kind of coplanar stripline optical switch—Pockles cell (Cr: GaAs—LiTaO_3). Electrical pulses with 10%—90% risetime of 1.5ps have been achieved by using electrooptic sampling. We have also measured the pulse width at different distances when the ps electrical pulse propagates along the coplanar stripline.     

Hardware reduction in continuous checksum-based analog checkers: Algorithm and its analysis

Fault-tolerant design of analog circuits is more difficult than that of digital circuits. Chatterjee has proposed a continuous checksum-based technique to design fault-tolerant linear analog circuits. However, hardware overhead of the embedded checker is an important issue in this technique, which has never been addressed before. This paper proposes an algorithm for reduction of hardware overhead in the checker. Without changing the original circuit, the proposed algorithm can not only reduce the number of passive elements, but also the number of analog operators so that the error detection circuitry in the checker has optimal hardware overhead. As the basis of the algorithm, a serial of theoretic results, including the concept and existence conditions of all-non-zero solutions, have also been presented to verify the algorithm.     

连续钛宝石激光器自锁模实验研究

用本所生长的掺钛宝石晶体和国内的元器件进行钛宝石激光器自锁模实验研究，获得了最窄脉冲宽度５３ｆｓ，谱宽１３ｕｍ，平均功率２００ｍＷ，调谐范围７５０～８５０ｎｍ的稳定激光脉冲序列。     

输出平均功率达200W的板状激光器

脉冲运转的“之”字形Nd:YAG板状激光器,在工作频率为50pps时,最高输出激光平均功率达230W。由于采用了“之”字形光路,使热畸变得到补偿,输出激光束的发散角得到改善,一般为3×4mrad。     

帧中继技术及其发展

文章介绍了帧中继技术及其应用,对帧中继接口协议、帧格式、网内控制及帧中继与其他网络的互通进行了详述,最后给出了中国帧中继网的组建情况以及今后发展前景。     

中学物理计算机辅助教学的软、硬件状况调查研究

将计算机技术应用于教育教学领域,是现代教育的重要特征,也是我国中小学教学改革的一项重要内容.为将计算机的先进技术更好地应用于中学物理教学,推动物理学科计算机辅助教学的发展,我们对297位中学物理教师和520位学生进行了有关物理CAI软、硬件的问卷调查.     

Ionic Covalent Organic Frameworks with Spiroborate Linkage

A novel type of ionic covalent organic framework (ICOF), which contains sp³ hybridized boron anionic centers and tunable countercations, was constructed by formation of spiroborate linkages. These ICOFs exhibit high BET surface areas up to 1259 m² g^?1 and adsorb a significant amount of H₂ (up to 3.11 wt %, 77 K, 1 bar) and CH₄ (up to 4.62 wt %, 273 K, 1 bar). Importantly, the materials show good thermal stabilities and excellent resistance to hydrolysis, remaining nearly intact when immersed in water or basic solution for two days. The presence of permanently immobilized ion centers in ICOFs enables the transportation of lithium ions with room‐temperature lithium‐ion conductivity of 3.05×10^?5 S cm^?1 and an average Li⁺ transference number value of 0.80±0.02. Our approach thus provides a convenient route to highly stable COFs with ionic linkages, which can potentially serve as absorbents for alternative energy sources such as H₂, CH₄, and also as solid lithium electrolytes/separators for the next‐generation lithium batteries.     

Nox reduction with CO over supported Pd catalysts under simulated post Euro-IV diesel exhaust conditions

The catalytic reduction of NO_x with CO over Pd/Al₂O₃ and Pd/TiO₂/Al₂O₃ under simulated post Euro-IV diesel exhaust conditions was studied. The catalytic activities obtained by using various Pd and TiO₂ loadings and total amounts of reductant and the influence of H₂ and H₂O was investigated.     

Translation of DNA into a library of 13,000 synthetic small-molecule macrocycles suitable for in vitro selection

DNA-templated organic synthesis enables the translation, selection, and amplification of DNA sequences encoding synthetic small-molecule libraries. Previously we described the DNA-templated multistep synthesis and model in vitro selection of a pilot library of 65 macrocycles. In this work, we report several key developments that enable the DNA-templated synthesis of much larger (>10,000-membered) small-molecule libraries. We developed and validated a capping-based approach to DNA-templated library synthesis that increases final product yields, simplifies the structure and preparation of reagents, and reduces the number of required manipulations. To expand the size and structural diversity of the macrocycle library, we augmented the number of building blocks in each DNA-templated step from 4 to 12, selected 8 different starting scaffolds which result in 4 macrocycle ring sizes and 2 building-block orientations, and confirmed the ability of the 36 building blocks and 8 scaffolds to generate DNA-templated macrocycle products. We computationally generated and experimentally validated an expanded set of codons sufficient to support 1728 combinations of step 1, step 2, and step 3 building blocks. Finally, we developed new high-resolution LC/MS analysis methods to assess the quality of large DNA-templated small-molecule libraries. Integrating these four developments, we executed the translation of 13,824 DNA templates into their corresponding small-molecule macrocycles. Analysis of the resulting libraries is consistent with excellent (>90%) representation of desired macrocycle products and a stringent test of sequence specificity suggests a high degree of sequence fidelity during translation. The quality and structural diversity of this expanded DNA-templated library provides a rich starting point for the discovery of functional synthetic small-molecule macrocycles.