A CNT-like coordination tube with cyano-bridges

Reaction of K2[Ru(bipy)(CN)4] with MnCl2 produces a novel bimetallic compound {Mn(H2O)2[Ru(bipy)(CN)4]} (bipy = 2,2'-bipydine), exhibiting a CNT-like structure bridged by cyanide groups and high thermal stability, which has been first observed in coordination polymers.     

Polarized photon-pairs heterodyne polarimetry for ultrasensitive optical activity detection of a chiral medium

A polarized photon-pairs heterodyne polarimetry is proposed in order to measure in an ultrasensitive manner the circular birefringence of a chiral medium via optical rotation detection. A balanced detector is integrated into this polarimeter. Thus, shot-noise-limited detection by this polarimeter can be achieved. Experimentally, the detection sensitivity for the circular birefringence of a glucose-water solution up to partial differential |n(r) - n(l)| = 2 x 10(-11) at 10 mg/dL is verified. To our knowledge, this is the highest sensitivity ever measured of a chiral liquid solution based on single traveling sample cell geometry. Finally, when compared to a fiber loop ring-resonator in the frequency domain for a chiral liquid, this polarimeter shows an order of 10(4) enhancement on the sensitivity of natural optical activity measurement.     

Synthesis, structure, and chirality of hydroxyl- and carboxyl-functionalized cubane-like photodimers of 2-naphthalene

Two novel hydroxyl- and carboxyl-functionalized cubane-like photodimers from methyl 2-naphthoate have been successfully achieved under mild conditions. X-ray crystal structures confirm that the cubane-like structure is well retained in these two derivatives and the intermolecular OH?O hydrogen bonding plays an important role in crystal packing. It is of significance that the isolated racemic mixture can be subsequently resolved into two optically pure enantiomers by high-performance liquid chromatography.     

Two novel dinuclear iron(III) complexes containing <Emphasis Type="Italic">μ</Emphasis>-oxo-di-<Emphasis Type="Italic">μ</Emphasis>-carboxylato motif

Two novel μ-oxo-di-μ-carboxylato-bridged iron(III) complexes of [Fe₂(bpea)₂(PhCO₂)₂(μ-O)] (ClO₄)₂·C₂H₅OH (1) and [Fe₂(bpma)₂(ClCH₂COO)₂(μ-O)](ClO₄)₂· H₂O (2) (bpea = N,N-bis(2-pyridylmethyl)ethylamine, bpma = N,N-bis(2-pyridylmethyl)methylamine), have been synthesized and determined by X-ray diffraction. Complex (1) crystallizes in the Orthorhombic space group P _nma with d(Fe···Fe) of 3.094 Å and average d(Fe–Ob_bridge) of 1.805 Å; Complex (2) crystallizes in the Monoclinic space group C ₂/c, with d(Fe···Fe) of 3.109 Å and average d(Fe–Ob_bridge) of 1.794 Å. The magnetic studies indicate a stronger antiferromagnetic interaction between iron(III) ions through μ-oxo-di-μ-carboxylato-bridge for complex (1), with J = ? 141.6 cm^?1.     

The skeletal rearrangement of gold- and platinum-catalyzed cycloisomerization of cis-4,6-dien-1-yn-3-ols: pinacol rearrangement and formation of bicyclo[4.1.0]heptenone and reorganized styrene derivatives

With gold and platinum catalysts, cis-4,6-dien-1-yn-3-ols undergo cycloisomerizations that enable structural reorganization of cyclized products chemoselectively. The AuCl3-catalyzed cyclizations of 6-substituted cis-4,6-dien-1-yn-3-ols proceeded via a 6-exo-dig pathway to give allyl cations, which subsequently undergo a pinacol rearrangement to produce reorganized cyclopentenyl aldehyde products. Using chiral alcohol substrates, such cyclizations proceed with reasonable chirality transfer. In the PtCl2-catalyzed cyclization of 7,7-disubstituted cis-4,6-dien-1-yn-3-ols, we obtained exclusively either bicyclo[4.1.0]heptenones or reorganized styrene products with varied substrate structures. On the basis of the chemoselectivity/structure relationship, we propose that bicyclo[4.1.0]heptenone products result from 6-endo-dig cyclization, whereas reorganized styrene products are derived from the 5-exo-dig pathway. This proposed mechanism is supported by theoretic calculations.     

Identification of human hepatocellular carcinoma-related proteins by proteomic approaches

Hepatocellular carcinoma (HCC) is the most common malignant liver tumor. Analysis of human serum from HCC patients using two-dimensional gel electrophoresis (2DE) combined with nano-high-performance liquid chromatography electrospray ionization tandem mass spectrometry (nano-HPLC–ESI-MS/MS) identified fourteen different proteins differentially expressed between HCC patients and the control group. Twelve proteins were up-regulated and two down-regulated. By using nano-HPLC–MS/MS system to analyze proteome in human serum, 317 proteins were identified, twenty-nine of which to high confidence levels (protein matched at last two unique peptide sequences). Of these twenty-nine proteins, six were present only in HCC patients and may serve as biomarkers for HCC. Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users.     

2D warp-and-woof interwoven networks constructed by helical chains with different chirality

Two unprecedented 2D entangled layers of warp-and-woof threads interwoven by left- and right-handed helical chains, {[Mn(salen)Au(CN)2]4(H2O)}n (salen = N,N'-ethylenebis(salicylideneaminato)) and {Mn(acacen)Ag(CN)2}n (acacen = N,N'-ethylenebis(acetylacetonylideneiminate)) 2, have been synthesized and characterized.     

An unprecedented ambipolar charge transport material exhibiting balanced electron and hole mobilities

2,7-Bis(4-tert-butylphenyl)-9,9'-spirobifluorene exhibits balanced electron and hole mobilities of up to 10(-3) cm(2) V(-1) s(-1), as measured using time-of-flight techniques.     

New series of indium formates: hydrothermal synthesis, structure and coordination modes

Three new indium(III) compounds, In(HCOO)3 (1), In2(HCOO)5(OH) (2), and In(HCOO)2(OH) (3), were synthesized under hydrothermal conditions and characterized by single crystal and powder X-ray diffraction experiments, as well as by IR spectroscopy, elemental analysis, and coupled TG-DSC-MS measurement. All of these compounds adopt 3D framework structures consisting of InO6 octahedra and the 2.11 binding modes of formate with the (syn, syn-; syn, anti-; anti, anti-) configurations. The structural investigation of these indium formates reveals that the gradual introduction of the hydroxyl groups into the structures induces the polymerization of the InO6 octahedra, that is, InO6 is isolated in 1, becomes dimeric in 2, and finally forms 1D chains in 3. In addition, a simple formula that may be used for estimating the overall coordination number of the formate in Ma(HCOO)bLc is proposed.     

Lanostane-type triterpenoids from Diospyros discolor

Four new lanostane-type triterpenes, 24-ethyl-3beta-methoxylanost-9(11)-en-25-ol (1), 3beta-methoxy-24-methylenelanost-9(11)-en-25-ol (2), 3beta-methoxy-25-methyl-24-methylenelanost-9(11)-en-21-ol (3) and 3beta-methoxy-24-methyllanosta-9(11),25-dien-24-ol (4) together with three known triterpenes, betulinaldehyde, betulinic acid methyl ester, and ursaldehyde have been isolated from the methanol extract of the twigs of Diospyros discolor. The structures of those new compounds were elucidated by spectroscopic methods.