Investigation on activating individual living monocytic U937 cell by interleukin-6 using Raman tweezers

We investigate the activation of living monocytic U937 cells induced by interleukin-6 （IL-6） at the single cell level. We employ home-built Raman tweezers to measure the Raman spectra of living U937 cells with and without IL-6 at the single cell level. Raman peaks of amide III, amide I, DNA backbone, as well as guanine and adenine in U937 cells, change at 1312, 1652, 1090, and 1576 cm ？1 , respectively, shortly after IL-6 is added in the medium. The change is a dynamic temporal process. In the activation process of U937 cells induced by IL-6, the protein signals recover in 20 min, while the nucleic acid signals continue to increase for 20 min. The results reveal that the biochemical cascades of activation in signal transduction induced by IL-6 can be investigated in situ at the single cell level.     

新型氟代三苯胺衍生物的合成和光谱特性研究

设计和合成了一种新型氟代三苯胺衍生物——N,N,N′,N′-四苯基-[2′,2″,3′,3″,5′,5″,6′,6″-八氟对四联苯]-4,4″′-二胺(OFTPA)。通过元素分析、熔点测定、红外光谱和1 H NMR谱等手段对OFTPA的分子结构进行了表征,并对其主要的红外光谱吸收峰和1 H NMR谱带进行了归属分析。利用紫外-可见吸收光谱、荧光光谱和循环伏安法(CV)对OFTPA的电子能级结构和发光性能进行了研究。紫外-可见吸收光谱测定结果表明,OFTPA薄膜的最大吸收峰波长为355nm,光学带隙(Eg)为3.09eV。荧光光谱测定结果表明,OFTPA薄膜在365nm紫外光的激发下,产生发光峰波长在448nm附近、半峰宽(FWHM)为68nm的蓝光发射,色纯度高,有望成为优良的蓝光发射材料。循环伏安法测定结果表明,OFTPA的最高占有轨道(HOMO)能级为-5.41eV,最低空轨道(LUMO)能级为-2.32eV,具有良好的空穴传输性能。研究结果为进一步研究其在有机光电器件中的应用提供了参考。     

用于双色全息存储(Fe,Cu)∶LiNbO3晶体的参量优化计算

在确定Cu在LiNbO3晶体中对应于365 nm和633 nm的激发系数、复合系数、光伏系数的基础上,采用龙格库塔(Runge-Kutta)数值方法理论研究了双掺杂(Fe,Cu)∶LiNbO3晶体的深浅能级的掺杂组分比、氧化还原状态对双色全息存储的记录灵敏度和动态范围的影响,并探讨了同时取得尽可能大的灵敏度和动态范围的晶体条件。结果表明,为了同时得到较大的记录灵敏度和动态范围,在实际应用中选用浅能级掺杂浓度为5.0×1025m-3,深能级掺杂浓度为3×1024~3×1025m-3之间的弱氧化晶体是合适的。     

奇异介子光生反应的QCD描述

从低能QCD有效拉氏量出发,利用重子夸克结构的[SU_SF(6)⊙O(3)]_sym.⊙SU_c(3)波函数,研究了在核子上的奇异介子光生反应.计算了γ+p→K⁺+Λ反应的微分截面.结果表明:与传统唯象的强子理论相比,仅有一个自由参数(即强相互作用耦合常数)的QCD理论成功地描述了反应过程,很好地解释了实验结果.     

Micromachined Uncooled IR Bolometer Linear Array Using VO2 Thin Films

Mixed vanadium oxide thin films, as VO₂ for the main composition are materials for uncooled microbolometer due to their high temperature coefficient of resistance (TCR) at room temperature. This paper describes the design and fabrication of 8-element linear array IR uncooled microbolometers using the films and micromachining technology. The characteristics of the array is investigated in the spectral region of 8–12 m. The fabricated detectors exhibit responsivity of up to 10 KV/W, typical detectivity of 1.89×10⁸ cmHz^1/2/W, and thermal time constant of 11 ms, at 296 K and at a frequency of 30 Hz. Furthermore, The uncorrected response uniformity of the linear array bolometers is less than 20%.     

Interaction of longitudinal phonons with discrete breather in strained graphene

We numerically analyze the interaction of small-amplitude phonon waves with standing gap discrete breather (DB) in strained graphene. To make the system support gap DB, strain is applied to create a gap in the phonon spectrum. We only focus on the in-plane phonons and DB, so the issue is investigated under a quasi-one-dimensional setup. It is found that, for the longitudinal sound waves having frequencies below 6 THz, DB is transparent and thus no radiation of energy from DB takes place; whereas for those sound waves with higher frequencies within the acoustic (optical) phonon band, phonon is mainly transmitted (reflected) by DB, and concomitantly, DB radiates its energy when interacting with phonons. The latter case is supported by the fact that, the sum of the transmitted and reflected phonon energy densities is noticeably higher than that of the incident wave. Our results here may provide insight into energy transport in graphene when the spatially localized nonlinear vibration modes are presented.     

大口径KDP晶体角度相位匹配离线测量精度研究

为满足惯性约束聚变(ICF)实验对激光驱动器高效三倍频能力的要求, 对离线测量晶体角度相位匹配方案进行了优化。采取的主要优化措施是：提高晶体准直技术能力;降低模拟小口径激光输出变化对测量不稳定性的影响。通过理论分析和对实际测量结果的系统分析,得到了晶体离线测量的不确定度：其中二倍频相位匹配角测量扩展不确定度为15.94 rad,三倍频相位匹配角测量扩展不确定度为27.8 rad,达到了较高的晶体离线测量精度要求。     

硅单粒子位移损伤多尺度模拟研究

本文结合分子动力学方法和动力学蒙特卡罗方法, 研究了单个粒子入射硅引起的位移损伤缺陷的产生和演化过程; 基于Shockley-Read-Hall理论计算了单个粒子入射引起的位移损伤缺陷导致的泄漏电流增加及其演化过程, 比较了缺陷退火因子与泄漏电流退火因子之间的差异, 并将计算结果与实验值进行了对比. 结果表明, 计算泄漏电流时, 仅考虑一种缺陷的情况下缺陷退火因子与泄漏电流退火因子相同, 考虑两种缺陷类型情况下二者在数值上有所区别, 但缺陷退火因子仍能在一定程度上反映泄漏电流的退火行为. 分子动力学模拟中采用Stillinger-Weber势函数和Tersoff势函数时缺陷退火因子和泄漏电流退火因子与实验结果一致, 基于Stillinger-Weber势函数的计算结果与实验值更为接近.     

电磁弹射灭火弹消防系统研究

首先介绍了我国严峻的火灾形势,阐明现有气动和火箭发射灭火弹装置的研究现状,针对射程不足、火工品使用限制等问题,提出采用电磁线圈发射器发射灭火弹进行灭火,基于电流丝模型法设计了一种10级线圈发射器模型,以脉冲电容器作为初始能源,采用续流电路对线圈进行时序放电,可将7.2 kg抛体加速至最高速度171 m/s,出口速度154 m/s,发射效率达15%,分析表明现有电磁线圈发射器能够满足灭火弹的发射需要。提出一种智能化无人电磁弹射灭火弹消防系统,智能指挥控制系统利用无人机采集火场信息,制定灭火策略,指挥无人电磁发射灭火车发射灭火弹实现精准高效灭火,根据灭火效能评估结果调整灭火方案,直至完成灭火任务。