Anti-neuraminidase activity of chemical constituents of Balanophora involucrata

Balanophora involucrata J. D. Hooker has been known to possess potential anti-inflammatory and antibacterial activities; however, its antiviral activity has not been evaluated so far. In order to find new neuraminidase inhibitors (NAIs), the neuraminidase (NA) inhibition activity of different B. involucrata extracts was evaluated. In this study, an in vitro NA inhibition assay was performed to identify which extract of B. involucrata exhibits (maximal) inhibitory activity against NA. Ultra high performance liquid chromatography/quadrupole time-of-flight–tandem mass spectroscopy (MS/MS) and molecular docking techniques were used to identify the specific compounds responsible for the anti-influenza activity of the extract, and to explore the potential natural NAIs. The ethyl acetate extract of B. involucrata exhibited significant inhibitory activity against NA with 50% inhibitory concentration (IC₅₀) value of 159.5 μg/mL. Twenty compounds were identified according to the MS/MS spectra; among them two compounds (quercitrin and phloridzin) showed obvious inhibitory activity against NA, with IC₅₀ of 311.76 and 347.32 μmol/L, respectively. This study suggested that B. involucrata can be a potential natural source of NAIs and may be useful in the fight against ferocious influenza viruses.     

Solving nonnegative sparsity-constrained optimization via DC quadratic-piecewise-linear approximations

Journal of Global Optimization - In this paper, we propose a novel algorithm that is based on quadratic-piecewise-linear approximations of DC functions to solve nonnegative sparsity-constrained...     

Al2O3陶瓷激光铣削试验研究

采用Nd∶YAG脉冲激光器对Al2 O3陶瓷进行铣削加工试验。系统研究了工艺参数对铣削量和铣削面质量的影响规律 ,并利用优化的铣削工艺对Al2 O3陶瓷进行多种形状的铣削加工。     

Windows2000设备驱动程序即插即用的实现

概述了Windows2000即插即用系统组成及其实现过程,结合实例介绍了Windows2000设备驱动程序如何支持用户即插即用的功能。     

电子天平示值误差测量结果的不确定度评定

一切测量结果都不可避免地具有不确定度，结合实际应用的情况，详细介绍了电子天平示值误差测量结果的不确定度评定方法。     

个性化公开密钥系统的设计

论文提出利用用户提供的个性化信息来随机产生关联大素数,保证了素数选取的随机化、个性化,提高了RSA算法的安全性。     

浅谈DC/DC变换器控制新方法

文中针对DC/DC变换器的特点,在现有控制和建模方法的基础之上,对DC/DC变换器的现代控制方法进行了归纳和总结,简要讨论了其控制原理,并比较了各种现代控制方法的优缺点,最后对DC/DC变换器控制方法的发展作了一定的展望。     

Iterative detection/decoding for two-track partial response channels

In this letter, we investigate the iterative detection/decoding algorithms for two-track partial response channels. We first describe the iterative algorithm as an iterative message-passing/processing algorithm over a high-level normal graph and then propose two trellis-based detection algorithms. The natural one is based on a joint trellis, which can be implemented for low-order channels. For moderate-order channels, we propose a separated detection, which is based on two single-track trellises. Compared with the joint detection, the separated detection is simpler in most cases. Simulation results show that, for two-track EPR4 channels with minor intertrack interferences, the separated detection causes only marginal degradation in performance.     

基于MPEG-2文件的合并

介绍了具有相同音频、视频编码方式的MPEG - 2节目流如何合并成一个节目流。合并后的文件播放流畅并且时间显示正确 ,它包括PATPMT表的重写 ,系统头部分相关字段的更改 ,PCR值的修改 ,解码时间标签 (DTS)和显示时间标签 (PTS)的重新确定 ,传送速率的修改以及添加相应的空包     

通信性能评估的仿真实验研究

研究了流量控制和差错控制对通信性能的综合影响，着重分析了停止-等待协议和连续ARQ协议的优缺点，讨论了信道利用率和帧长的关系。介绍了几种多点接人技术的基本原理，如CSMA和CSMA／CD，并给出了各自相应的性能仿真曲线。所设计的通信性能评估实验，仿真界面形象丰富，与实验知识点紧密结合，可以大大提高实验教学的效率和质量。