Forces between mica surfaces, prepared in different ways, across aqueous and nonaqueous liquids confined to molecularly thin films

We have measured normal and lateral interactions across a range of different liquids between mica surfaces using a surface force balance (SFB). The mica surfaces were prepared either by melt cutting using Pt wire and standard procedures in our laboratories or by tearing sheets (that had not been exposed to Pt) off from a freshly cleaved sheet of mica. AFM micrographs revealed the substantial absence of Pt nanoparticles on the melt cut and torn-off mica surfaces. Normal-force versus surface-separation (D) profiles and shear force versus D measurements for purified water (no added salt), for concentrated aqueous NaCl solutions, and for cyclohexane revealed that in all cases the behavior of the highly confined liquids between melt-cut and between torn-off mica sheets was identical within experimental scatter. These results demonstrate directly that interactions measured between melt-cut mica surfaces as routinely prepared using established procedures in our laboratories and in other laboratories are free of the effect of any Pt contamination.     

Directed self-assembly of gold-tipped CdSe nanorods

Gold-tipped CdSe rods (nanodumbbells) were solubilized in an aqueous phase and self-assembled in a head-to-tail manner using biotin disulfide and avidin. The disulfide end of the biotin molecule attaches to the gold tip of the nanodumbbell, and the biotin end of the molecule is able to conjugate to an avidin protein. The avidin can strongly conjugate up to four biotin molecules. Changing the ratios of biotin to nanodumbbells leads to the formation of dimers, trimers, and flowerlike structures. To further improve the distribution of chain lengths, a separation method based upon weight was applied using a concentration gradient. The gold tips provide effective anchor points for constructing complex nanorod structures by self-assembly.     

Stable radicals formation in coals undergoing weathering: effect of coal rank

Once coal is excavated it comes into contact with atmospheric oxygen and begins to undergo low temperature oxidation. The mechanism by which the molecular oxygen interacts with the coal macromolecule is suggested to occur in several steps. These steps primarily involve O(2) diffusion to the surface where physical adsorption followed by chemical adsorption takes place. The chemical adsorption forms several types of oxides that can subsequently react to form several products, primarily CO(2). It has also been suggested that some of these oxidation mechanisms might involve radical reactions. As the previous studies were conducted under conditions where significant structural changes occur it is possible that in the low temperature range (T < 100 °C) the oxidation mechanism is different. Several different rank (lignite-subbituminous-bituminous) coals were isothermally heated at 95 °C in an air atmosphere for a period of up to 6 months and samples were collected at two week intervals. The radical concentration of each sample was measured by Continuous Wave Electron Paramagnetic Resonance (CW-EPR). It is apparent that there are distinct differences between the lower rank (lignite) and the higher rank (subbituminous, bituminous) coals. The lower rank coals exhibited only carbon centered radicals with an adjacent oxygen atom and the higher rank coals exhibited only carbon centered radicals. Interestingly, the lower rank coals exhibited no change in radical concentration due to the long term oxidation treatment while the higher rank coals showed a distinct increase in the radical concentration. These findings shed new light on the complex heterogeneous low temperature oxidation reactions occurring at the coal surface.     

RNA encapsidation by SV40-derived nanoparticles follows a rapid two-state mechanism

Remarkably, uniform virus-like particles self-assemble in a process that appears to follow a rapid kinetic mechanism. The mechanisms by which spherical viruses assemble from hundreds of capsid proteins around nucleic acid, however, are yet unresolved. Using time-resolved small-angle X-ray scattering (TR-SAXS), we have been able to directly visualize SV40 VP1 pentamers encapsidating short RNA molecules (500mers). This assembly process yields T = 1 icosahedral particles comprised of 12 pentamers and one RNA molecule. The reaction is nearly one-third complete within 35 ms, following a two-state kinetic process with no detectable intermediates. Theoretical analysis of kinetics, using a master equation, shows that the assembly process nucleates at the RNA and continues by a cascade of elongation reactions in which one VP1 pentamer is added at a time, with a rate of approximately 10(9) M(-1) s(-1). The reaction is highly robust and faster than the predicted diffusion limit. The emerging molecular mechanism, which appears to be general to viruses that assemble around nucleic acids, implicates long-ranged electrostatic interactions. The model proposes that the growing nucleo-protein complex acts as an electrostatic antenna that attracts other capsid subunits for the encapsidation process.     

More results in polychromatic Ramsey theory

We study polychromatic Ramsey theory with a focus on colourings of [ω ₂]². We show that in the absence of GCH there is a wide range of possibilities. In particular each of the following is consistent relative to the consistency of ZFC: (1) 2 ^ω = ω ₂ and \(\omega _2 \to ^{poly} (\alpha )_{\aleph _0 - bdd}^2 \) for every α <ω ₂; (2) 2 ^ω = ω ₂ and \(\omega _2 \nrightarrow ^{poly} (\omega _1 )_{2 - bdd}^2 \).     

Incentive regulation and the change in productive efficiency in telecommunications in the United States

Incentive regulation has become an important regulatory tool in the telecommunications industry in the United States. The issue explored here is whether incentive regulation has resulted in an increase in productive efficiency. After providing an overview of the nature of incentive regulation, a methodology for measuring technical inefficiency and its change is introduced. This is a stochastic frontier production function approach reflecting technical inefficiency effects. The results of implementing this methodology suggest that in the production of interLATA billed access minutes for interstate calls, there was no change in technical efficiency, something that incentive regulation was specifically designed to enhance. Finally, an assessment of technical efficiency across individual LECs in the United States indicates considerable variability. Published in 2001 by John Wiley & Sons, Ltd.     

Polynomial-time algorithms for regular set-covering and threshold synthesis

A set-covering problem is called regular if a cover always remains a cover when any column in it is replaced by an earlier column. From the input of the problem - the coefficient matrix of the set-covering inequalities - it is possible to check in polynomial time whether the problem is regular or can be made regular by permuting the columns. If it is, then all the minimal covers are generated in polynomial time, and one of them is an optimal solution. The algorithm also yields an explicit bound for the number of minimal covers. These results can be used to check in polynomial time whether a given set-covering problem is equivalent to some knapsack problem without additional variables, or equivalently to recognize positive threshold functions in polynomial time. However, the problem of recognizing when an arbitrary Boolean function is threshold is NP-complete. It is also shown that the list of maximal non-covers is essentially the most compact input possible, even if it is known in advance that the problem is regular.     

Routing in Queues with Delayed Information

We compare two routing-control strategies in a high-speed communication network with c parallel channels (routes), where information on service completions in down-stream servers is randomly delayed. The controller can either hold arriving messages in a common buffer, dispatching them to servers only when the delayed information becomes available (Wait option), or route jobs to the various channels, in a round-robin fashion, immediately upon their arrival. Interpreting the delays as servers's vacations and considering overall queue sizes as a measure of performance, we show that the Wait strategy is superior as long as the mean information delay is below a threshold. We calculate threshold values for various combinations of load and c and show that, for a given load, the threshold increases with c and, for fixed c, the threshold decreases with an increasing load. If information is delayed on arrival instants, rather than on service completions, we show that the system can be viewed as a tandem queue and derive a generalization of a queue-decomposition result obtained by Altman, Kofman and Yechiali.