蟹,虾壳微观形貌与结构研究

用Ｘ射线衍射与扫描电镜研究了蟹壳，虾壳的形貌与微观结构，蟹壳中以方解石晶型存在的碳酸钙分布在网状结构的有机质中，网孔的尺寸约５～２５μｍ有机基质脱去蛋白后留下的甲壳质呈片层状结构，它的重复距离为０．９６ｎｍ。     

迭代Suzuki偶联反应合成全氟环丁基芳基醚齐聚物的研究

对迭代Suzuki偶联反应合成全氟环丁基芳基醚齐聚物的方法进行了研究, 并合成了全氟环丁基芳基醚齐聚物. 首先从对溴苯酚出发, 合成了含有一个全氟环丁基芳基醚结构单元的中间体3. 芳基硼酸与中间体3进行Suzuki偶联反应, 得到了含有一个全氟环丁基芳基醚结构单元的硼酸. 重复与中间体3进行Suzuki偶联反应, 从而合成了全氟环丁基芳基醚二聚体和三聚体. 最后通过热环化二聚反应合成了全氟环丁基芳基醚三聚体、五聚体和七聚体.     

A DNA crystal designed to contain two molecules per asymmetric unit

We describe the self-assembly of a DNA crystal that contains two tensegrity triangle molecules per asymmetric unit. We have used X-ray crystallography to determine its crystal structure. In addition, we have demonstrated control over the colors of the crystals by attaching either Cy3 dye (pink) or Cy5 dye (blue-green) to the components of the crystal, yielding crystals of corresponding colors. Attaching the pair of dyes to the pair of molecules yields a purple crystal.     

低温等离子体与MnO_x/γ-Al_2O_3协同催化降解正己醛

研究了在低温等离子体和催化剂共同作用下低浓度正己醛的降解反应.结果表明,等离子体与γ-Al2O3之间产生了很好的催化协同作用,在低放电功率(2.8W)和低温(80℃)下,干燥空气气氛中,γ-Al2O3对0.12%正己醛的去除率为87.1%;当γ-Al2O3负载7.5%MnOx后,正己醛去除率达到96.5%,其效果与Pt/γ-Al2O3相当.7.5%MnOx/γ-Al2O3在实验条件下连续使用50h,其催化活性未见下降.     

Synthesis,Crystal Structure and Fluorescent Study of Bis(2-(2-hydroxyphenyl)benzimidazolate)zinc with Ethanol Solvate

Abstract  The zinc(II) complex with 2-(2-hydroxyphenyl)benzimidazole, namely [Zn(2-(2-hydroxyphenyl)benzimidazolate)₂]·C₂H₅OH (1 · C₂H₅OH) has been synthesized and characterized by X-ray crystallography and photoluminescent analysis. The complex crystallizes in monoclinic space group P2₁/c with cell parameters a = 10.156(1) ?, b = 25.771(3) ?, c = 9.674(1) ?, α = 90°, β = 103.641(2)°, γ = 90°, Z = 4, V = 2460.4(4) ?³. The central Zn(II) is four-coordinate and has a tetrahedral geometry. The steady-state and time-resolved photoluminescent spectra for the title compound have also been studied. The emission property can be ascribed to ligand-centered charge-transfer transition (LCCT) with π → π* property. Index Abstract   A new co-crystal of Zn(II) complex of 2-(2-hydroxylphenyl)benzimidazole with ethanol solvate has been prepared, characterized by X-ray crystallography and fluorescent studies.      

激光烧蚀下不同颗粒度Al-teflon的反应行为

为研究不同颗粒度对Al-teflon反应行为的影响,以颗粒度25μm、1μm和20～200 nm的Al粉和微米级Teflon粉混合制备的反应材料为研究对象,基于脉冲激光烧蚀实验,结合ICCD相机和光谱仪对反应过程中的自发光成像和发射光谱进行瞬态观测。研究结果表明,Al-teflon反应材料在激光烧蚀下的反应行为体现出典型的二次反应特征,具有持续燃烧特征和明显的后燃效应,也具有较长的能量释放时间;同时,其反应行为与Al粉颗粒度密切相关:初始阶段,反应随Al粉颗粒度的降低加剧,随着反应的进行,纳米级Al粉对应的反应材料后续反应能力逐渐下降,反应强度和反应时间都小于1μm铝粉对应的反应材料。     

Performance optimization of the elliptically vibrating screen with a hybrid MACO-GBDT algorithm

As a typical screening apparatus,the elliptically vibrating screen was extensively employed for the size classification of granular materials.Unremitting effort...     

板栗内皮对水溶液中镉离子和铅离子的吸附

研究了板栗内皮对水溶液中金属离子(Cd2+,Pb2+)的吸附过程,以及吸附过程中不同条件对其吸附能力的影响.通过对反应时间、温度、pH、初始金属离子浓度等因素的控制,设计不同单一变量确定在不同条件下的吸附能力,利用红外光谱确定板栗内皮上参与反应的主要基团.结果表明,板栗内皮吸附Cd2+,Pb2+理论最佳吸附条件分别为p...     

Quantification of Venetoclax for Therapeutic Drug Monitoring in Chinese Acute Myeloid Leukemia Patients by a Validated UPLC-MS/MS Method

Venetoclax has emerged as a breakthrough for treatment of leukemia with a wide interindividual variability in pharmacokinetics. Herein, a rapid, sensitive, and reliable UPLC-MS/MS method for quantification of venetoclax in plasma was developed and validated. The method was operated in the multiple-reaction monitoring (MRM) mode to detect venetoclax at m/z transition 868.5 > 321.0 and IS at 875.5 > 321.0, respectively. Protein precipitation prior to injection into the LC-MS/MS and the analyte was separated on an ACQUITY UPLC BEH C18 column by gradient elution with acetonitrile and 0.1% formic acid in water. Linear calibration curves were obtained in the range of 25–8000 ng/mL. The specificity, recovery, matrix effect, and stability also met the acceptance criteria of FDA guidance. The method was successfully applied to analyze plasma in acute myeloid leukemia (AML) patients. The peak plasma concentration (C_max) of venetoclax in Chinese AML patient was 2966.0 ± 1595.0 ng/mL while the trough concentration (C_min) was 1018.0 ± 729.4 ng/mL. Additionally, C_max and C_min showed a positive correlation with AST levels. Furthermore, C_max was significantly higher in the older patients. The present method can be applied for TDM of venetoclax in treatment of hematological cancers.     

Routes to control of H2 Coulomb explosion in few-cycle laser pulses

We have measured coincident ion pairs produced in the Coulomb explosion of H2 by 8-30 fs laser pulses at different laser intensities. We show how the Coulomb explosion of H2 can be experimentally controlled by tuning the appropriate pulse duration and laser intensity. For laser pulses less than 15 fs, we found that the rescattering-induced Coulomb explosion is dominated by first-return recollisions, while for longer pulses and at the proper laser intensity, the third return can be made to be the major one. Additionally, by choosing suitable pulse duration and laser intensity, we show H2 Coulomb explosion proceeding through three distinct processes that are simultaneously observable, each exhibiting different characteristics and revealing distinctive time information about the H2 evolution in the laser pulse.