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31.
Previous work carried out in our laboratories has focused on the formation and investigation of a dextran and concanavalin A (con A) based gel, which has the ability to alter its conformational structure in the presence and absence of free and terminal glucoses such that a gel–sol phase transition occurs. Here we report the diffusion and rheological investigations in to the effects of the addition of insulin and varyingconcentrations of magnesium chloride hexahydrate (Mg2Cl26H2O) at 20 and 37 °C. Rheological examination of glucose-sensitive (dextran-con A) gels were conducted using a cone and plate viscometer used in continual rotation and oscillatory modes. The results are interpreted in terms of the structure of the gel network and suggest rheological assessment provides an effective method of assessing the properties of gel systems. The subsequent testing of such formulations in in-vitro diffusion experiments revealed a reduction in the rate of diffusivity in the insulin marker, poly R-478 dye. The performance of this self-regulating drug delivery system has been examined and the addition of insulin and magnesium chloride may alter the way in which the gel operates as a drug delivery device and in the delivery of insulin. This may have implications for other ligands. 相似文献
32.
Millisecond pulsars: nature's most stable clocks 总被引:8,自引:0,他引:8
Taylor J.H. Jr. 《Proceedings of the IEEE. Institute of Electrical and Electronics Engineers》1991,79(7):1054-1062
The author describes the role pulsars might play in time and frequency technology. Millisecond pulsars are rapidly rotating neutron stars: some 20 km in diameter, 1.4 times as massive as the Sun, and spinning as fast as several thousand radians per second. Radio noise generated in a pulsar's magnetosphere by a highly beamed process is detectable over interstellar distances, as a periodic sequence of pulses. High-precision comparisons between pulsar time and terrestrial atomic time show that over intervals of several years, some millisecond pulsars have fractional stabilities comparable to those of the best atomic clocks. The author briefly reviews the physics of pulsars, discusses the techniques of pulsar timing measurements, and summarizes the results of careful studies of pulsar stabilities 相似文献
33.
Using the time differential perturbed angular correlation technique, the hyperfine interactions as titanium sites in ZnTiF6·6H2O and its decomposition products were determined between room temperature (300 K) and 1273 K. The different steps in the decomposition pattern were identified and a simple model is given for it. 相似文献
34.
Rü diger W. Braun Reinhold Meise B. A. Taylor 《Proceedings of the American Mathematical Society》2003,131(8):2423-2433
We give a sufficient condition for a local radial Phragmén-Lindelöf principle on analytic varieties. This condition is expressed in terms of existence of hyperbolic directions.
35.
36.
Generation of 100 GHz trains of 500-700 fs pulses using dual-frequency beat conversion in a step-like dispersion profiled fibre is reported. The authors believe that this is the first time the generation and compression of soliton pulses using such a fibre has been demonstrated. The fabrication of such fibre assemblies does not require any special facilities and relies only on conventional optical fibre technology. They believe that the use of profiling the fibre dispersion by fibre segments instead of continuously dispersion-decreasing fibre is not only possible but preferable in many applications 相似文献
37.
This paper describes a fixed-weight Hamming binary neural classifier chip suitable for applications where high-speed operation is required. The circuit uses switched current-mode techniques throughout and achieves classification in one forward pass through the network. The chip was realized in 2.4-μm n-well CMOS technology and was designed to recognize the integers 0-9. It achieved a classification rate of 10 MHz without any observable tendency to misclassification or instability 相似文献
38.
This paper reports the results of a survey intended to discover the extent to which Checkland's Soft Systems Methodology (SSM) is used in practice. Some 300 questionnaires were sent to people who had had some exposure to SSM and, surprisingly, nearly half were returned. The majority described in detail their uses of SSM and most felt that it had been successful. This paper describes the overall quantitative results from the survey as well as presenting a qualitative analysis of the experiences of using SSM. 相似文献
39.
We have demonstrated a temperature switch based on an optically bistable device integrated with an optical fibre. The principle demonstrated here might lead to the development of new types of all-optical temperature sensors. 相似文献
40.
D. W. Taylor V. Villas-Boas Q. Lu M. F. Rossignol F. P. Missell D. Givord S. Hirosawa 《Journal of magnetism and magnetic materials》1994,130(1-3):225-236
We studied the coercivity in magnets of composition R17Fe83−χBχ (R = Nd, Pr and χ = 8, 30), using measurements of the coercive field Hc, its angular dependence, and the magnetic viscosity coefficient Sv, for temperatures between 4.2 and 500 K. The results are discussed in relation to a model which does not specifically consider the detailed mechanisms involved in magnetization reversal, but which provides information about the magnetic properties in the activation volume v where magnetization reversal is initiated. It is concluded that the ordering temperature in v tends to be slightly smaller than in the bulk and that the room temperature anisotropy in v is not strongly reduced with respect to the bulk value. Finally, a direct evaluation of the dipolar interactions is in good agreement with results obtained from Hc(T). 相似文献