平行缝焊工艺的热效应研究

平行缝焊作为一种高可靠性的气密性密封方法,在陶瓷封装行业中有着愈发重要的应用。封焊过程中瞬间产生的高能量在完成密封的同时,会对陶瓷外壳造成很高的热应力残留,可能会对器件可靠性产生影响。介绍了平行缝焊的工作原理及工艺参数,并通过使用ANSYS软件对工艺过程中的各参数进行热仿真分析,研究平行缝焊工艺参数对陶瓷封装的热影响。     

基于FPGA的电机伺服器设计

文中针对传统的8位单片机由于计算功能等条件限制和系统内部体系结构,在实现各种高效的控制算法和先进的电机控制理论时面临的着成本高,系统复杂程度高等问题.该设计采用模糊比例算法,即在大范围内采用模糊控制,以提高系统的动态响应速度,建立系统模型.通过现场可编程门阵列FPGA的数字电子系统对电机进行控制,以硬件电路算法实现算法程序,将原来的电路板级产品集成为芯片级产品,为电动机数字控制提供了一种新的有效方法.该设计的优点:低功耗,可靠性高,低成本.     

基于有限元的脉冲激光辐照材料温度场研究

在激光超声检测过程中,为了合理加载脉冲激光的能量,以便获得幅值较大的超声波信号,同时避免脉冲激光造成材料的损伤,需要对脉冲激光辐照材料的温升进行数值计算。依据有限元理论,建立脉冲激光辐照材料的有限元模型,结合导热微分方程,将脉冲激光以热流密度的形式加载于材料表面,分析材料表层受激光辐照时的温度场,讨论有限元热分析时网格尺寸的选取对分析结果的影响。给出了材料表层受脉冲激光辐照时温度场的计算方法和网格尺寸的选择依据,并利用温度场的理论解析结果和应力场分析结果分别验证了温度场有限元计算方法的正确性和有效性。     

基于MATLAB的声表面波标签数据采集与处理

利用Matlab控制数字示波器,实现声表面波-射频识别(SAW-RFID)系统数据采集的功能,以获取示波器采集的标签编码回波信号。上位机在Matlab上进行了显示界面的设计,利用最大相关法对采集的回波信号作算法解调处理,最终完成了声表面波射频识别系统的搭建。     

基于设计模式的ADS-B终端软件设计与实现

简介了广播式自动相关监视系统(ADS-B)的工作原理、数据格式等,设计并实现了ADS-B地面站的显示终端软件,利用设计模式实现了软件模块间的解耦,提高了软件复用度。软件人机界面友好、操作简单,在相关领域具有较好的应用价值。     

TD-SCDMA网络重要性浅谈

在国内4G快速发展的背景下,3G网络逐步被取代以承载移动宽带用户的数据流量,因而国内涌现了很多认为3G网络如TD-SCDMA已过时的观点,本文通过对中国移动现网用户的数据承载、自主知识产权技术积累、国内外通信体制的博弈、国内4G的发展和人才培养等方面进行分析,显示了TD-SCDMA仍发挥着重要的作用。     

TIBO衍生物类抗艾滋病药物三维定量结构活性关系研究

采用三维全息原子场作用矢量(3D-HoVAIF)对20个TIBO类衍生物抗艾滋病药物进行定量构效关系(QSAR)研究。运用偏最小二乘回归(Partial Least Square Regression,PLS)建模,同时采用内部及外部双重验证的办法对所得模型稳定性能进行深入分析和检验。PLS建模的复相关系数(Rcum)、留一法(Leave-one-out,LOO)交互校验(Cross-validation,CV)复相关系数(QCV)和外部样本校验复相关系数(Qext)分别为0.837、0.804、0.812。结果表明,3D-HoVAIF能较好表征TIBO类衍生物抗艾滋病药物分子结构信息,     

Effects of Divalent Metal Ions on the Chaperone Activity and Structure of Rat Lens H18G Mutant αB‐Crystallin

αB‐crystalin, a small heat shock protein and a component of α‐crystalin, is a molecular chaperone playing an important role in preventing the formation of cataracts. It has been reported that His18 is an important site for Cu²⁺ to bind with to form a stable metal complex and thus to enhance this chaperone‐like activity of human αB‐crystalin. In this work, we used site‐directed mutagenesis to clone and express H18G rat lens αB‐crystalin in order to investigate the role of His18 in chaperoning activity. We found that 1 mM of Cu²⁺, or Zn²⁺, rather than Mg²⁺, significantly enhanced the chaperone‐like activity of wild type αB‐crystalin. Whereas, it is Zn²⁺ and Mg²⁺, not Cu²⁺, that significantly reduced this activity of H18G αB‐crystalin. In the absence of cation, H18G showed better activity compared to the wild type αB‐crystalin. ANS fluorescence measurement showed there was no linear relationship between chaperone‐like activity and surface hydrophobicity, indicating that surface hydrophobicity is not a prerequisite for chaperone‐like activity. An HPLC size‐exclusion chromatography study showed that in the presence of metal ions, wild type αB‐crystalin tended to aggregate via dissociation and re‐association into a high molecular aggregate with a molecular weight higher than 1400 kDa and then precipitated, suggesting that the presence of metal ions is a factor leading to the formation of cataracts. Both the near and far UV‐CD spectra suggested that the wild type αB‐crystalin reflected more β‐sheet structural characteristics; whereas the H18G reflected more random coil characteristics. The H18G induced structural alterations as to develop more random coil characteristics and more micro‐environmental changes around the tryptophan residues. This work suggested that His18 may not be a crucial binding site for Cu²⁺, but rather that it may be an important binding site for Zn²⁺ in terms of chaperone‐like activity and the process of metal induced self‐aggregation is prerequisite for chaperone‐like activity to occur.     

Solvent‐Free Aerobic Chemoselective Oxidation of β‐Ionone catalyzed by N‐Hydroxyphthalimide/Co(acac)2

β‐Ionone was oxidized with O₂ under solvent‐free conditions catalyzed by an N‐hydroxyphthalimide/Co(acac)₂ system in mild conditions with high conversion and excellent selectivity to oxo‐β‐ionone or 5,6‐epoxy‐β‐ionone in different reaction conditions, respectively.