全文获取类型
收费全文 | 1151篇 |
免费 | 73篇 |
国内免费 | 5篇 |
专业分类
化学 | 927篇 |
晶体学 | 1篇 |
力学 | 16篇 |
数学 | 131篇 |
物理学 | 96篇 |
无线电 | 58篇 |
出版年
2024年 | 4篇 |
2023年 | 18篇 |
2022年 | 24篇 |
2021年 | 38篇 |
2020年 | 46篇 |
2019年 | 37篇 |
2018年 | 17篇 |
2017年 | 21篇 |
2016年 | 45篇 |
2015年 | 41篇 |
2014年 | 43篇 |
2013年 | 61篇 |
2012年 | 92篇 |
2011年 | 103篇 |
2010年 | 59篇 |
2009年 | 61篇 |
2008年 | 86篇 |
2007年 | 77篇 |
2006年 | 75篇 |
2005年 | 61篇 |
2004年 | 58篇 |
2003年 | 44篇 |
2002年 | 39篇 |
2001年 | 12篇 |
2000年 | 10篇 |
1999年 | 5篇 |
1998年 | 3篇 |
1997年 | 7篇 |
1996年 | 7篇 |
1995年 | 4篇 |
1994年 | 5篇 |
1989年 | 2篇 |
1984年 | 1篇 |
1982年 | 1篇 |
1948年 | 2篇 |
1946年 | 1篇 |
1945年 | 1篇 |
1939年 | 2篇 |
1938年 | 1篇 |
1936年 | 1篇 |
1935年 | 1篇 |
1933年 | 2篇 |
1929年 | 2篇 |
1927年 | 2篇 |
1917年 | 1篇 |
1891年 | 1篇 |
1890年 | 1篇 |
1889年 | 1篇 |
1885年 | 1篇 |
1884年 | 1篇 |
排序方式: 共有1229条查询结果,搜索用时 31 毫秒
41.
An HPLC‐ECD method for monoamines and metabolites quantification in cuttlefish (cephalopod) brain tissue
下载免费PDF全文
![点击此处可从《Biomedical chromatography : BMC》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Flavie Bidel Sophie Corvaisier Christelle Jozet‐Alves Ivannah Pottier François Dauphin Nadège Naud Cécile Bellanger 《Biomedical chromatography : BMC》2016,30(8):1175-1183
The cuttlefish belongs to the mollusk class Cephalopoda, considered as the most advanced marine invertebrates and thus widely used as models to study the biology of complex behaviors and cognition, as well as their related neurochemical mechanisms. Surprisingly, methods to quantify the biogenic monoamines and their metabolites in cuttlefish brain remain sparse and measure a limited number of analytes. This work aims to validate an HPLC‐ECD method for the simultaneous quantification of dopamine, serotonin, norepinephrine and their main metabolites in cuttlefish brain. In comparison and in order to develop a method suitable to answer both ecological and biomedical questions, the validation was also carried out on a phylogenetically remote species: mouse (mammals). The method was shown to be accurate, precise, selective, repeatable and sensitive over a wide range of concentrations for 5‐hydroxyindole‐3‐acetic acid, serotonin, dopamine, 3,4‐dihydroxyphenylacetic acid and norepinephrine in the both extracts of cuttlefish and mouse brain, though with low precision and recovery for 4‐hydroxy‐3‐methoxyphenylethylene glycol. Homovanillic acid, accurately studied in rodents, was not detectable in the brain of cuttlefish. Overall, we described here the first fully validated HPLC method for the routine measurement of both monoamines and metabolites in cuttlefish brain. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献
42.
43.
Clromatic sensitivity along the protan, deutan, and tritan lines and the loci of the unique hues (red, green, yellow, blue) for a very large sample (n = 185) of colour-normal observers ranging from 18 to 75 years of age are assessed. Visual judgments are obtained under normal viewing conditions using colour patches on self-luminous display under controlled adaptation conditions. Trivector discrimination thresholds show an increase as a function of age along the protan, deutan, and tritan axes, with the largest increase present along the tritan line, less pronounced shifts in unique hue settings are also observed. Based on the chromatic (protan, deutan, tritan) thresholds and using scaled cone signals, we predict the unique hue changes with ageing. A dependency on age for unique red and unique yellow for predicted hue angle is found. We conclude that the chromatic sensitivity deteriorates significantly with age, whereas the appearance of unique hues is much less affected, remaining almost constant despite the known changes in the ocular media. 相似文献
44.
45.
Ultrasmall Superparamagnetic Iron Oxide Nanoparticles with Europium(III) DO3A as a Bimodal Imaging Probe
下载免费PDF全文
![点击此处可从《Chemistry (Weinheim an der Bergstrasse, Germany)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Dr. Sophie Carron Dr. Maarten Bloemen Prof. Luce Vander Elst Prof. Sophie Laurent Prof. Thierry Verbiest Prof. Tatjana N. Parac‐Vogt 《Chemistry (Weinheim an der Bergstrasse, Germany)》2016,22(13):4521-4527
A new prototype consisting of ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles decorated with europium(III) ions encapsulated in a DO3A organic scaffold was designed as a platform for further development of bimodal contrast agents for MRI and optical imaging. The USPIO nanoparticles act as negative MRI contrast agents, whereas the europium(III) ion is a luminophore that is suitable for use in optical imaging detection. The functionalized USPIO nanoparticles were characterized by TEM, DLS, XRD, FTIR, and TXRF analysis, and a full investigation of the relaxometric and optical properties was conducted. The typical luminescence emission of europium(III) was observed and the main red emission wavelength was found at 614 nm. The relaxometric study of these ultrasmall nanoparticles showed r2 values of 114.8 mm ?1Fes?1 at 60 MHz, which is nearly double the r2 relaxivity of Sinerem®. 相似文献
46.
47.
48.
49.
50.
Aurica Farcas Giulia Tregnago Ana‐Maria Resmerita Sarah Taleb Dehkordi Sophie Cantin Fabrice Goubard Pierre‐Henri Aubert Franco Cacialli 《Journal of polymer science. Part A, Polymer chemistry》2014,52(4):460-471
The photophysical properties of two polyrotaxanes ( PFBTh?PSβCD and PFBTh?PMeβCD ) composed of fluorene and bithiophene encapsulated into permodified β‐cyclodextrin cavities have been investigated and compared with those of the reference PFBTh . Rotaxane formation results in improvements of the thermal stability, solubility in common organic solvents, as well as better film forming ability combined with a high transparency. As expected PFBTh and its encapsulated forms absorb at wavelengths beyond 510 nm, and time‐resolved photoluminescence (PL) in solution shows a well‐define vibronic structures with a predominance of the 0‐0 transitions and an energy difference of 0.16 eV. The fluorescence lifetimes follow a monoexponential decay with a value τ = 630 ± 30 ps. Atomic force microscopy, AFM, indicated a tendency of polyrotaxanes to organize into fibers. The advancing contact angles indicated higher surface hydrophobicity and lower surface free‐energy values for polyrotaxanes compared with their unthreaded analogues. The device based on PFBTh?PSβCD: PCBM in a 1/1 w/w ratio under simulated AM 1.5G illumination at 100 mW cm?2 exhibited improved photovoltaic parameters of cells, resulted in high Voc (0.68 V), Jsc (1.65 mA cm?2), FF (31.6%), and PCE (0.35) values, compared with PFBTh or PFBTh?PMeβCD , respectively. © 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2014 , 52, 460–471 相似文献