Design rules for an integratable low-power amplifier/filter combination

In this paper design rules for a circuit topology in which there is an inseparable combination of an amplifier and a filter characteristic, are presented. By intentionally using the capacitance of an already present input sensor for the filtering, the total required integrated capacitance is much less than that in circuits, which have a separately designed amplifier and filter function. Consequently, it is possible to have the advantage of a better integratability. Moreover, less complexity in the design is achieved. The presented circuit shows a current-to-voltage conversion and an inherently controllable second-order low-pass filter characteristic. A discrete realization has been designed to test the circuit. This circuit operates down to a 1 V supply voltage and the transfer shows a 1.8 M currentto-voltage conversion with a bandwidth of 6 kHz. Measurement results of this circuit show that a 63 dB dynamic range can be achieved with a total required integrated capacitance of only 31 pF.     

The formation of dimetallocycles from reactions of alkynes with (η-C5Me5)2Rh2(CO)2; X-ray structure of [(η-C5Me5)2Rh2(η-CO) {μ-η2,η2-C(O)C2-(CF3)2}]

The complexes (η-C₅Me₅)₂Rh₂(μ-CO) {μ-η²,η²-C(O)CRCR} are obtained from reactions between (η-C₅Me₅)₂Rh₂(CO)₂ and the alkynes RCCR (R  CF₃, CO₂Me, or Ph) at 25°C. The molecular geometry of the complex with R  CF₃ has been established by X-ray diffraction; the bridging 'ene-one' unit adopts a μ-η²,η² conformation. Other complexes isolated from these reactions include (η-C₅Me₅)Rh(C₆R₆) (R  CF₃, CO₂Me), (η-C₅Me)₂Rh₂(C₄R₄) (R  CO₂Me) and (η-C₅Me₅)₂Rh₂(CO₂C₂R₂) (R  Ph). The reaction between (η-C₅Me₅)₂Rh₂(CO)₂ and C₆F₅CCC₆F₅ gives (η-C₅Me₅)₂Rh₂(CO)₂(C₆F₅C₂C₆F₅). Mononuclear complexes such as (η-C₅Me₅)Co(C₄R₄CO) are the major products isolated from reactions between (η-C₅Me₅)₂CO₂(CO)₂ and alkynes at 25°C.     

The stimulated raman scattering process for possible use in photoselective isotope enrichment

The process of stimulated Raman scattering (SRS) is discussed as a means of achieving sizeable transient populations in the first vibrationally excited state of one species out of an isotopic mixture. This may be useful for photoselective isotope enrichment schemes. The main advantage of SRS excitation is the possibility of using one fixed-wavelength laser for the study of various compounds; also there is an inherent tendency to selectivity in SRS since the more abundant species in an isotopic mixture will show a higher gain for SRS. Sample calculations are presented showing Q-switched solid-state lasers to be good sources for selective excitation of gaseous mixtures, while mode-locked laser pulses are required for liquid samples.     

Characterization of phosphopeptides from protein digests using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and nanoelectrospray quadrupole time-of-flight mass spectrometry

A two-step mass spectrometric method for characterization of phosphopeptides from peptide mixtures is presented. In the first step, phosphopeptide candidates were identified by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) based on their higher relative intensities in negative ion MALDI spectra than in positive ion MALDI spectra. The detection limit for this step was found to be 18 femtomoles or lower in the case of unfractionated in-solution digests of a model phosphoprotein, beta-casein. In the second step, nanoelectrospray tandem mass (nES-MS/MS) spectra of doubly or triply charged precursor ions of these candidate phosphopeptides were obtained using a quadrupole time-of-flight (Q-TOF) mass spectrometer. This step provided information about the phosphorylated residues, and ruled out nonphosphorylated candidates, for these peptides. After [(32)P] labeling and reverse-phase high-performance liquid chromatography (RP-HPLC) to simplify the mixtures and to monitor the efficiency of phosphopeptide identification, we used this method to identify multiple autophosphorylation sites on the PKR-like endoplasmic reticulum kinase (PERK), a recently discovered mammalian stress-response protein.     

PHOTO-CIDNP DETECTION OF PYRIMIDINE DIMER RADICAL CATIONS IN ANTHRAQUINONESULFONATE- SENSITIZED SPLITTING

Anthraquinone-2-sulfonate (AQS) photosensitizes pyrimidine dimer splitting. Electron abstraction from the dimer is thought to induce dimer splitting, but direct evidence for the existence and intermediacy of dimer radical cations has been lacking. By employing photochemically induced dynamic nuclear polarization, we have found emission signals in the NMR spectra of dimers upon photolysis of dimers in the presence of anthraquinone-2-sulfonate. The two dimers employed were cis, syn-thymine dimer in which the N(1)-positions were linked by a three-carbon bridge and the N(3), N(3')-dimethyl derivative of that compound. The anthraquinone-2-sulfonate sensitized photochemically induced dynamic nuclear polarization spectrum of the methylated derivative exhibited an emission signal from the dimer-C(6) hydrogens. This result implied the existence of a dimer radical cation (mD+.) formed by electron abstraction by excited anthraquinone-2-sulfonate and nuclear spin sorting within a solvent caged radical ion pair [mD+. AQS-.]. Product pyrimidine photochemically induced dynamic nuclear polarization signals were also seen [enhanced absorption by C(6)-hydrogens and emission by C(5)-methyl groups]. Nuclear spin polarization in the product resulted from spin sorting in one or more of its precursors, including mD+. The results support the conclusion that dimer radical cations not only exist but are intermediates in the photosensitized splitting of pyrimidine dimers by anthraquinonesulfonate.     

The structure of projection-valued states: A generalization of Wigner's theorem

A projection-valued state is defined to be a completely orthoadditive map from the projections on one Hilbert space into the projections on another Hilbert space, which preserves the unit. Any such mapping is shown to have the formP U ₁(P 1₁)U ₁ ^–1 U ₂(P 1₂)U ₂ ^–1 , whereU ₁ is unitary andU ₂ is antiunitary, generalizing Wigner's theorem on symmetry transformations. A physical interpretation is given and the relation to quantum logic is discussed.The contents of this paper are a portion of the author's dissertation at the University of Massachusetts at Amherst.     

A parallel implementation of the COLUMBUS multireference configuration interaction program

Summary In this work a parallel implementation of the COLUMBUS MRSDCI program system is presented. A coarse grain parallelization approach using message passing via the portable toolkit TCGMSG is used. The program is very well portable and runs on shared memory machines like the Cray Y-MP, Alliant FX/2800 or Convex C2 and on distributed memory machines like the iPSC/860. Further implementations on a network of workstations and on the Intel Touchstone Delta are in progress. Overall, results are quite satisfactory considering the complexity and the prodigious requirements, especially the I/O bandwidth, of MRCI programs in general. For our largest test case we obtain a speedup of a factor of 7.2 on an eight processor Cray Y-MP for that section of the program (hamiltonian matrix times trial vector product) which has been parallelized. The speedup for one complete diagonalization iteration amounts to 5.9. An absolute speed close to 1 GFLOPS is found. Results for the iPSC/860 show that ordinary disk I/O is certainly not sufficient in order to guarantee a satisfactory performance. As a solution for that problem, the implementation of a fully asynchronous distributed-memory model for certain data files is in preparation. On leave from: Bereich Informatik, Universität Leipzig, Augustusplatz 10/11, O-7010 Leipzig, Germany     

Rapid intramolecular interactions between organic isocyanates and hexafluorobut-2-yne on a dirhodium centre; X-ray crystal structure of (η-C5H5)2Rh2 {μ2(η3-C(CF3)C(CF3)C(O)N(Ph)}

Complexes of formula (η-C₅H₅₂Rh₂{CF₃C₂CF₃ · RNCO} have been prepared by three methods, from reactions between organic isocyanates and (η-C₅H₅)₂Rh₂(CO)(CF₃C₂CF₃) or (η-C₅H₅)₂Rh₂(CO)₂(CF₃C₂CF₃); by treatment of (η-C₅H₅)₂Rh₂(CO)(CF₃C₂CF₃) with organic azides; and by oxidation with Me₃NO of the organic isocyanide in (η-C₅H₅)₂Rh₂(CO)(CNR)(CF₃C₂CF₃). The crystal and molecular structure of the complex (η-C₅H₅)₂Rh₂{CF₃C₂CF₃ · RNCO} with R = Ph has been determined from single crystal X-ray diffraction data. This reveals that the isocyanate has condensed with the hexafluorobut-2-yne to form an amide ligand of the form C(CF₃)C(CF₃)C(=O)N(R); this bridges the two rhodium atoms in a μ₂η³-manner.