电源处理单元配置方案可靠性比较及选择

电推进技术是航天推进技术一个重要的发展方向.针对新一代通信卫星平台电推进系统的需求,对用于电推进系统的电源处理单元的4种备选配置方案做了介绍,并对每种方案的可靠性进行了计算.通过可靠性指标对比和对配置方案的分析,为方案优选提供了一些依据.     

红外焦平面阵列非均匀性自适应校正算法研究

在分析红外焦平面阵列非均匀性校正现行算法的基础上,提出了一种具有自适应性能的新算法。该算法以小波变换中的滤波器理论为基础,通过将图像序列在时间域的尺度分解和相庆统计量计算,获得在红外焦平面校正中起影响的偏置和增益系数。模拟实验结果验证了其有效性和先进性。     

基于改进小波包分析的导航设备故障诊断的特征提取

针对故障诊断信号特征提取问题,提出了小波包分析的改进算法,该算法通过对小波包分解系数的重新排序,解决了小波包分析的频带混叠问题,给出了应用改进小波包分析进行故障诊断特征提取的算法,并在此基础上提出了基于改进小波包分析预处理的神经网络故障字典法．通过仿真比较,该方法剔除了样本信号的冗余成分,大幅度地减少了神经网络的规模,加快了网络的收敛速度,为导航设备故障诊断的特征提取提供了行之有效的手段。     

Smart Injectable Hydrogels for Cancer Immunotherapy

Hydrogels, a class of materials with a 3D network structure, are widely used in various fields especially in biomedicine. Injectable hydrogels could facilitate the encapsulation and controlled release of small molecular drugs, macromolecular therapeutics, and even cells. With the rapid development of cancer immunotherapy, such injectable hydrogels have attracted wide attention for local immunomodulation to boost systemic anticancer immune responses, realizing more effective immunotherapy at lower doses. The latest progresses in the development of various smart injectable hydrogels for cancer immunotherapy are summarized here. Although applied locally, such injectable hydrogels can activate systemic antitumor immune responses, safely and effectively inhibiting the tumor metastasis and recurrence. Moreover, it is discussed how injectable hydrogel‐based cancer immunotherapy would contribute to the development of next generation of cancer treatment together with their potential for clinical translation.     

基于改进遗传算法和LVQ神经网络包裹算法的特征筛选

在皮肤症状计算机辅助测试系统研究中，症状特征的筛选是提高系统诊断的关键问题，针对这个问题提出基于遗传算法和LVQ神经网络相结合的包裹算法。同时为了提高搜索效率，采用改进的自适应遗传算法。并用留一交叉法验证LVQ神经网络分类器的识别率．对初步提取的体现病态皮肤症状特点的22个特征以及它们的10个随意组合构成的干扰项进行特征选择，选择出使皮肤症状诊断率得到明显提高的特征组合。实验证明该方法是可行的。     

基于深度学习的激光干扰效果评价方法

针对激光干扰效果评估受主观经验较大、难以定量评估的问题,提出了一种基于深度学习的激光干扰效果评估方法.首先,对YOLOV5算法进行了整体介绍,其次制作了来自不同角度、不同距离的3020张激光干扰图像;然后,对标注的数据集进行训练,得到了激光干扰效果评估模型;最后,分别在YOLOV5x、YOLOV51、YOLOV5m、YOLOV5s网络模型下训练300次,实验验证了模型的正确性.实验结果表明:利用训练好的模型实现了对激光干扰图像的效果评估,该模型不仅可以自动标注激光干扰区域和进行干扰效果等级评估,同时还融入了传统策略,可以通过计算标注区域面积占整幅图像面积的大小作为辅助决策,实现自动标注激光干扰区域面积所占百分比,识别准确度在80％以上,对激光干扰效果评估具有重要意义.     

Fluorobenzotriazole (FTAZ)‐Based Polymer Donor Enables Organic Solar Cells Exceeding 12% Efficiency

The fluorobenzotriazole (FTAZ)‐based copolymer donors are promising candidates for nonfullerene polymer solar cells (PSCs), but suffer from relatively low photovoltaic performance due to their unsuitable energy levels and unfavorable morphology. Herein, three polymer donors, L24 , L68 , and L810 , based on a chlorinated‐thienyl benzodithiophene (BDT‐2Cl) unit and FTAZ with different branched alkyl side chain, are synthesized. Incorporation of a chlorine (Cl) atom into the BDT unit is found to distinctly optimize the molecular planarity, energy levels, and improve the polymerization activity. Impressively, subtle side chain length of FTAZ realizes a dramatic improvement in all the device parameters, as revealed by the short‐current density (J_sc) improved from 7.41 to 20.76 mA cm^?2, fill‐factor from 36.3 to 73.5%, and even the open‐circuit voltage (V_oc) from 0.495 to 0.790 V. The best power conversion efficiency (PCE) of 12.1% is obtained from the L810‐based device, which is one of the highest values reported for FTAZ‐based PSCs so far. Notably, the corresponding external quantum efficiency curve keeps a very prominent value up to 80% from 500 to 800 nm. The notable performance is discovered from the reduced energy loss, improved molecular face‐on orientation, the down‐shifted energy levels, and optimized absorption coefficient regulated by side‐chain engineering.     

基于ACTELFPGA短波红外成像系统设计与研究

针对短波红外探测在各个领域的重要作用,采用Sofradir 320×256短波红外探测器,基于ACTEL公司的FPGA芯片APA600,设计并实现了短波红外成像系统,并对几个关键性设计进行了分析。该系统具有低功耗、小体积、高速率、可控性好等特点。实验结果表明该系统能够满足设计要求。     

基于PLC的空压机冗余控制系统设计

虽然空压机一般都自带控制系统,但是当多台空压机并网运行时,则需要额外的控制器做协调.本文设计了以嵌入式触摸屏上位机和PLC为核心建立起来的7台空压机PLC冗余联控系统,从控制系统结构设计方面进行了详细的分析和论证;论述了空压机的自动联控运行的PLC程序设计方法和控制流程;实现了PLC的电源冗余、CPU冗余、总线冗余及与上位机的工业以太网冗余和I/O模块的热拔插.与传统空压机控制系统相比,有效降低了成本,并提高了系统的可靠性.     

A Low‐Toxic Multifunctional Nanoplatform Based on Cu9S5@mSiO2 Core‐Shell Nanocomposites: Combining Photothermal‐ and Chemotherapies with Infrared Thermal Imaging for Cancer Treatment

Copper chalcogenides have been demonstrated to be a promising photothermal agent due to their high photothermal conversion efficiency, synthetic simplicity, and low cost. However, the hydrophobic and less biocompatible characteristics associated with their synthetic processes hamper widely biological applications. An alternative strategy for improving hydrophilicity and biocompatibility is to coat the copper chalcogenide nanomaterials with silica shell. Herein, the rational preparation design results in successful coating mesoporous silica (mSiO₂) on as‐synthesized Cu₉S₅ nanocrystals, forming Cu₉S₅@mSiO₂‐PEG core‐shell nanostructures. As‐prepared Cu₉S₅@mSiO₂‐PEG core‐shell nanostructures show low cytotoxicity and excellent blood compatibility, and are effectively employed for photothermal ablation of cancer cells and infrared thermal imaging. Moreover, anticancer drug of doxorubicin (DOX)‐loaded Cu₉S₅@mSiO₂‐PEG core‐shell nanostructures show pH sensitive release profile and are therefore beneficial to delivery of DOX into cancer cells for chemotherapy. Importantly, the combination of photothermal‐ and chemotherapies demonstrates better effects of therapy on cancer treatment than individual therapy approaches in vitro and in vivo.