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51.
JPC – Journal of Planar Chromatography – Modern TLC - A sensitive, specific, and accurate stability-indicating high-performance thin-layer chromatographic method for the analysis of... 相似文献
52.
The present study for the first time explores the use of Central composite design (CCD) of RSM to optimize the process parameters of biosynthesis of AgNPs from rhizome extract of Curculigo orchioides based on the absorbance of surface plasmon resonance (SPR) band at 430 nm that corresponds to the synthesis of mono-disperse, spherical AgNPs. A polynomial model was established as a functional relationship between the synthesis of AgNPs and four independent variables such as concentration of AgNO3, % rhizome extract, pH and temperature. The optimum conditions for maximum AgNPs synthesis were 2 mM concentration of AgNO3, 20 % rhizome extract, pH 8, and temperature of 60 °C. A significant correlation (R 2 = 0.8947) was observed between the experimental data and the predicted values indicating the adequacy of the model. Transmission electron microscopy (TEM) revealed spherical particles with size range of 5–28 nm. Selected area electron diffraction pattern and X-ray diffraction analysis confirmed the face-centered cubic structure of metallic silver. The plausible mechanism for the reduction of AgNO3 to AgNPs was proposed following the identification of functional groups by FTIR. The antioxidative activity of AgNPs was demonstrated with scavenging of hydrogen peroxide (H2O2), 1,1-Diphenyl-2-picrylhydrazyl (DPPH) and superoxide radicals. 相似文献
53.
Biocatalytic Synthesis of Allylic and Allenyl Sulfides through a Myoglobin‐Catalyzed Doyle–Kirmse Reaction
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Dr. Vikas Tyagi Dr. Gopeekrishnan Sreenilayam Dr. Priyanka Bajaj Antonio Tinoco Prof. Dr. Rudi Fasan 《Angewandte Chemie (International ed. in English)》2016,55(43):13562-13566
The first example of a biocatalytic [2,3]‐sigmatropic rearrangement reaction involving allylic sulfides and diazo reagents (Doyle–Kirmse reaction) is reported. Engineered variants of sperm whale myoglobin catalyze this synthetically valuable C?C bond‐forming transformation with high efficiency and product conversions across a variety of sulfide substrates (e.g., aryl‐, benzyl‐, and alkyl‐substituted allylic sulfides) and α‐diazo esters. Moreover, the scope of this myoglobin‐mediated transformation could be extended to the conversion of propargylic sulfides to give substituted allenes. Active‐site mutations proved effective in enhancing the catalytic efficiency of the hemoprotein in these reactions as well as modulating the enantioselectivity, resulting in the identification of the myoglobin variant Mb(L29S,H64V,V68F), which is capable of mediating asymmetric Doyle–Kirmse reactions with an enantiomeric excess up to 71 %. This work extends the toolbox of currently available biocatalytic strategies for the asymmetric formation of carbon–carbon bonds. 相似文献
54.
This paper describes the heavy ion-induced effects on the electrical characteristics of reactively sputtered ZrO2 and Al2O3 high-k gate oxides deposited in argon plus nitrogen containing plasma. Radiation-induced degradation of sputtered high-k dielectric ZrO2/Si and Al2O3/Si interface was studied using 45?MeV Li3+ ions. The devices were irradiated with Li3+ ions at various fluences ranging from 5?×?109 to 5?×?1012?ions/cm2. Capacitance–voltage and current–voltage characteristics were used for electrical characterization. Shift in flat band voltage towards negative value was observed in devices after exposure to ion radiation. Post-deposition annealing effect on the electrical behavior of high-k/Si interface was also investigated. The annealed devices showed better electrical and reliability characteristics. Different device parameters such as flat band voltage, leakage current, interface defect density and oxide-trapped charge have been extracted.The surface morphology and roughness values for films deposited in nitrogen containing plasma before and after ion radiation are extracted from Atomic Force Microscopy. 相似文献
55.
Priyanka Mohan Sumathi Rao 《The European Physical Journal B - Condensed Matter and Complex Systems》2016,89(9):206
We use the SU(2) slave fermion approach to study a tetrahedral spin 1/2 chain, which is a one-dimensional generalization of the two dimensional Kitaev honeycomb model. Using the mean field theory, coupled with a gauge fixing procedure to implement the single occupancy constraint, we obtain the phase diagram of the model. We then show that it matches the exact results obtained earlier using the Majorana fermion representation. We also compute the spin-spin correlation in the gapless phase and show that it is a spin liquid. Finally, we map the one-dimensional model in terms of the slave fermions to the model of 1D p-wave superconducting model with complex parameters and show that the parameters of our model fall in the topological trivial regime and hence does not have edge Majorana modes. 相似文献
56.
One-step synthesis of oxazoline and dihydrooxazine libraries 总被引:1,自引:0,他引:1
Chaudhry P Schoenen F Neuenswander B Lushington GH Aubé J 《Journal of combinatorial chemistry》2007,9(3):473-476
The reactions of 1,2- and 1,3-hydroxyalkyl azides and aldehydes in the presence of Lewis acid result in the one-step construction of oxazolines and dihydrooxazines, respectively. The reaction was adapted to parallel synthesis using a polymer-bound phosphine to scavenge excess hydroxyalkyl azide. Thus, a 60-member library of various disubstituted oxazolines and di- and trisubstituted dihydrooxazines was generated. 相似文献
57.
The combined effect of relativistic and ponderomotive nonlinearities on the self‐focusing of an intense cosh‐Gaussian laser beam (CGLB) in magnetized plasma have been investigated. Higher‐order paraxial‐ray approximation has been used to set up the self‐focusing equations, where higher‐order terms in the expansion of the dielectric function and the eikonal are taken into account. The effects of various lasers and plasma parameters viz. laser intensity (a0), decentred parameter (b), and magnetic field (ωc) on the self‐focusing of CGLB have been explored. The results are compared with the Gaussian profile of laser beams and relativistic nonlinearity. Self‐focusing can be enhanced by optimizing and selecting the appropriate laser‐plasma parameters. It is observed that the focusing of CGLB is fast in a nonparaxial region in comparison with that of a Gaussian laser beam and in a paraxial region in magnetized plasma. In addition, strong self‐focusing of CGLB is observed at higher values of a0, b, and ωc. Numerical results show that CGLB can produce ultrahigh laser irradiance over distances much greater than the Rayleigh length, which can be used for various applications. 相似文献
58.
Taurine is a naturally occurring sulfur-containing amino acid that is found abundantly in excitatory tissues, such as the heart, brain, retina and skeletal muscles. Taurine was first isolated in the 1800s, but not much was known about this molecule until the 1990s. In 1985, taurine was first approved as the treatment among heart failure patients in Japan. Accumulating studies have shown that taurine supplementation also protects against pathologies associated with mitochondrial defects, such as aging, mitochondrial diseases, metabolic syndrome, cancer, cardiovascular diseases and neurological disorders. In this review, we will provide a general overview on the mitochondria biology and the consequence of mitochondrial defects in pathologies. Then, we will discuss the antioxidant action of taurine, particularly in relation to the maintenance of mitochondria function. We will also describe several reported studies on the current use of taurine supplementation in several mitochondria-associated pathologies in humans. 相似文献
59.
This paper presents propagation of two cross-focused intense hollow Gaussian laser beams(HGBs) in collisionless plasma and its effect on the generation of electron plasma wave(EPW) and electron acceleration process,when relativistic and ponderomotive nonlinearities are simultaneously operative. Nonlinear differential equations have been set up for beamwidth of laser beams, power of generated EPW, and energy gain by electrons using WKB and paraxial approximations. Numerical simulations have been carried out to investigate the effect of typical laser-plasma parameters on the focusing of laser beams in plasmas and further its effect on power of excited EPW and acceleration of electrons. It is observed that focusing of two laser beams in plasma increases for higher order of hollow Gaussian beams,which significantly enhanced the power of generated EPW and energy gain. The amplitude of EPW and energy gain by electrons is found to enhance with an increase in the intensity of laser beams and plasma density. This study will be useful to plasma beat wave accelerator and in other applications requiring multiple laser beams. 相似文献
60.
Priyanka Malik R.S. Gupta Rishu Chaujar Mridula Gupta 《Microelectronics Reliability》2012,52(1):151-158
In this paper, the RF performance for Gate Material Engineered-Trapezoidal Recessed Channel (GME-TRC) MOSFET has been investigated and the results so obtained are compared with Trapezoidal Recessed Channel (TRC) MOSFET and Rectangle Recessed Channel (RRC) MOSFET, using device simulators; ATLAS and DEVEDIT. Further, the impact of technology parameter variations in terms of negative junction depth (NJD), gate metal workfunction difference, substrate doping (NA) and corner angle, on GME-TRC MOSFET has also been evaluated. The simulation study shows the increase in transconductance and decrease in parasitic capacitance, which further contributes towards a significant improvement in cut-off frequency (ft) in GME-TRC MOSFET as compared to conventional TRC and RRC MOSFETs. Moreover, the significant enhancement in maximum available power gain (Gma), maximum transducer power gain (GMT), maximum unilateral power gain (MUG), maximum frequency of oscillation (fMAX) and stern stability factor (K) have also been observed for GME-TRC MOSFET due to reduced short channel effects (SCEs) and enhanced current driving capabilities. Further, the experimental data for grooved gate MOSFET has also been verified with the simulated data and a good agreement between their results is obtained. 相似文献