Expanse software for distributed call and connection control

The experimental ATM network services environment (EXPANSE) prototype provides an experimental testbed for multimedia multiparty telecommunications services over heterogeneous communications networks. The EXPANSE software architecture supports the functional separation of call and connection control. At the call control layer an object-oriented, transaction-based call model provides for the co-ordination of the negotiations among users for the establishment, modification and disconnection of telecommunications services. The connection control layer provides an object-oriented protocol for the dynamic establishment, modification and release of network connections which include the control and allocation of network resources required for multimedia multiparty services. The EXPANSE software includes an application programming interface (API) to the signalling protocol at the call control level. The API provides a uniform and powerful interface to the call model and allows different applications to co-ordinate the control of local resources and session state.     

Rapid,quantitative, solvent-free synthesis of medium-ring diaza heterocycles from diketene–acetone adduct and diamines

The synthesis of medium-ring heterocycles remains a challenge largely due to unfavorable energetic factors. We are reporting syntheses of 7–9-member diaza heterocycles that go to completion in 5 min, require no solvents, and are quantitative with the only byproducts being acetone and water. The reaction products could be isolated in pure form by simply placing the mixture under vacuum. The reaction sequence possesses many of the hallmarks of a click reaction.     

Comparison of the thermal behavior and conformational changes in partially and fully hydrated dipalmitoylphosphatidylcholine systems

The temperature dependence of conformational changes for partially and fully hydrated DPPC systems through two physicochemical techniques, namely DSC and Raman spectroscopy, is studied. DSC experiments have shown a different thermal behavior between the two considered systems, indicating the effective role of water in the thermal behavior. A temperature resolution of inter- and intramolecular interactions during the main melting phase transition was achieved by using three different Raman intensity ratios, which confirm that the main phase transition represents a two-stage transition. Van’t Hoff plots for the C–C, C–H, C=O and C₄N⁺ stretching modes, in a temperature range just below the main transition temperature, have been used to compare the thermodynamic parameters extracted by the two physicochemical techniques. The significance of these results can be summarized as follows: (a) DSC and Raman spectroscopy have shown complementary results indicating that DPPC exists in partially or fully hydrated states; (b) thermodynamic parameters ΔΗ and ΔS calculated in both techniques for the two different hydration states of DPPC were in harmony; (c) water more significantly affects the thermal and dynamic properties of fully hydrated DPPC bilayers than of the partially hydrated DPPC; and (d) water disturbs the head-group packing, the alkyl chains interactions and the mesophase region. It appears that the amount of water plays a vital role in the bilayer structure. As more and more extensive studies appear in the literature on biomolecules or drug membrane interactions, this information will be valuable in understanding the role of water in these interactions.     

Addressing the interdependence in providing fair and efficient bandwidth distribution in hybrid optical‐wireless networks

The convergence of optical and wireless technologies may offer a compelling network access infrastructure because these technologies combine major benefits such as large coverage in the wireless part and huge bandwidth in the optical part of the converged access network. The convergence of the passive optical networks with 4G wireless standards, such as the Worldwide Interoperability for Microwave Access and the Long Term Evolution, constitutes a quite attractive solution to meet the challenges of the modern bandwidth‐hungry access networks. One of the most important objective a modern access network has to address is the adequate bandwidth distribution to the final users. In addition, several other aims are emerged towards this goal, such as fairness and quality of service provisioning. The adversity of designing an efficient bandwidth distribution scheme for hybrid optical‐wireless access networks lies in the interdependence of both domains: the bandwidth distribution in the wireless domain depends on the optical transmission grant opportunities, while the bandwidth coordinator in the optical part has to be aware of the mobile user heterogeneity in the wireless domain. Moreover, the bandwidth decision‐making module in both networks has to be aware of providing a fair allocation independently of the number of mobile users or the traffic requests in the network. In this work, we endeavor to address the aforementioned challenges. A novel, fair, and efficient bandwidth distribution scheme is proposed for hybrid optical‐wireless access networks. By using weighted fairness provisioning techniques, the proposed scheme intends to alleviate the interdependence of the two domains, offering a fair and efficient bandwidth distribution to the mobile users. The weights are properly defined, by utilizing suitable optimization techniques such as the Lagrange multiplies, so as to incorporate the underlying features of each traffic requests, such as the population density and the propagation delay. Extensive simulation results indicate the capability of the proposed scheme, compared with other competitive allocation schemes, in provisioning a more efficient and fair bandwidth distribution in terms of latency, throughput, and packet drop ratio. Copyright © 2015 John Wiley & Sons, Ltd.     

Reductively labile PRINT particles for the delivery of doxorubicin to HeLa cells

A Trojan horse PRINT particle composition was developed that incorporates a reductively labile cross-linker to achieve activated release of doxorubicin in vitro. Particles of discrete size and shape (cube side length = 2 micron) containing 30 wt % of a disulfide-based cross-linker and 2 wt % doxorubicin were synthesized. This PRINT composition was shown to release doxorubicin in response to a reducing environment as measured by flow cytometry and was found to be highly proficient at killing HeLa cells in vitro.     

A MAC Protocol for Bursty Traffic Ad-Hoc Wireless LANs with Energy Efficiency

A Self-Adaptive Low Power MAC protocol with carrier sensing for ad-hoc Wireless LANs (WLANs), which is capable of operating efficiently under bursty traffic is proposed in this letter. The protocol utilizes a Learning Automaton structure at each station of the WLAN. Each such structure uses the network feedback to select the mobile station that will transmit. A low-power mode is implemented in order to significantly reduce the energy consumption of the protocol. Simulation results reveal that the low power mode of the proposed protocol reduces the average energy consumption at the mobile stations by as much as 70%.     

Controlling Intercell Interference in CDMA-based Fixed Wireless Networks Through Multirate Techniques

A number of research works have suggested a possible capacity advantage when employing direct sequence-code division multiple access (DS-CDMA) instead of the more common time division multiple access option for fixed broadband wireless access networks operating at millimeter-waves. The choice of this multiple access scheme, which, up to now, has not been foreseen by recent WiMax (worldwide interoperability for microwave access) standards, exhibits an improved performance in terms of cochannel interference in the upstream, even though it experiences higher interference in the downstream. The present paper focuses on enhancing the bottleneck downstream performance of fixed wireless networks by proposing a methodology for controlling the signal-to-interference ratio throughout the cell, so that all subscribers meet the given interference quality-of-service specifications. This is accomplished by exploiting the properties of a combination of multirate CDMA techniques. The paper describes a simple policy for code assignment, which is proved to be optimal, incorporating the effect of rain fading over multiple paths. The performance of the algorithm is tested against single code DS-CDMA both under long term channel statistics (static code assignment) and under dynamic channel effects (dynamic code assignment). The first test verifies the compliance of all sector subscribers with more demanding SIR specifications, while the second yields a significant improvement in terms of resource utilization.     

A Modified Loo Model with Partially Blocked and Three Dimensional Multipath Scattering: Analysis,Simulation and Validation

This paper presents a novel mobile fading channel model, belonging to the class of Loo models, in which the multipath power arrives both in three dimensions (3-D) and in two angular sectors at the azimuth receiver’s plane. Moreover shadowing affects the amplitude of the line of sight (LOS) component, making it time varying and following a lognormal distribution, as required for a Loo model. The Doppler power spectral density (PSD) is analytically calculated, after Fourier transforming the closed form autocorrelation function. Afterwards exact solutions for the probability density function (PDF) of the envelope and phase are presented. What follows are approximate solutions for the second order statistics, i.e. the level crossing rate (LCR) and the average duration of fades (ADF’s). A new, appropriate for 3-D scattering cases, deterministic simulation scheme is developed, which implements the analytical model on a digital computer and is used to test the validity of the approximate solutions. Moreover the deterministic model is thoroughly investigated for all the possible cases, in terms of its convergence to the analytical one. Finally a curve fitting of the LCR to real world data, drawn from channel measurements, will demonstrate the flexibility and usefulness of the modified Loo model.     

Quantum Covers in Quantum Measure Theory

Sorkin’s recent proposal for a realist interpretation of quantum theory, the anhomomorphic logic or coevent approach, is based on the idea of a “quantum measure” on the space of histories. This is a generalisation of the classical measure to one which admits pair-wise interference and satisfies a modified version of the Kolmogorov probability sum rule. In standard measure theory the measure on the base set Ω is normalised to one, which encodes the statement that “Ω happens”. Moreover, the Kolmogorov sum rule implies that the measure of any subset A is strictly positive if and only if A cannot be covered by a countable collection of subsets of zero measure. In quantum measure theory on the other hand, simple examples suffice to demonstrate that this is no longer true. We propose an appropriate generalisation, the quantum cover, which in addition to being a cover of A, satisfies the property that if the quantum measure of A is non-zero then this is also the case for at least one of the elements in the cover. Our work implies a non-triviality result for the coevent interpretation for Ω of finite cardinality, and allows us to cast the Peres-Kochen-Specker theorem in terms of quantum covers.