Rainwater rivulets running on a stay cable subject to wind

Stay cables are likely to vibrate under the combined effect of rain and wind in the so-called phenomenon rain–wind-induced vibrations (RWIVs). Rain takes part in the phenomenon in the shape of water rivulets that run along the cables. In previous articles, the authors investigated the conditions under which such rivulets can be formed. Using a lubrication model, it was shown for a particular wind–cable configuration that rivulets can only be exhibited above a critical wind speed for which gravity is overcome. The rivulets’ position was also predicted with the model. The results were validated by experiments.In this paper, the wind speed at which rivulets appear and their position are expressed for an arbitrary wind–cable orientation. A maximum wind speed for the rivulets’ existence is then estimated as the result of a balance between the drag force and the surface tension. A wind speed interval is consequently obtained for the rivulets’ appearance and maintenance on a cylinder. The boundaries of this interval are expressed in term of Weber numbers, comparing the surface tension and wind effect. These predictions are successfully compared with all the measurements that have been published in the literature.     

Crystallization mechanisms of acicular crystals

In this contribution, we present an experimental investigation of the growth of four different organic molecules produced at industrial scale with a view to understand the crystallization mechanism of acicular or needle-like crystals. For all organic crystals studied in this article, layer-by-layer growth of the lateral faces is very slow and clear, as soon as the supersaturation is high enough, there is competition between growth and surface-activated secondary nucleation. This gives rise to pseudo-twinned crystals composed of several needle individuals aligned along a crystallographic axis; this is explained by regular over- and inter-growths as in the case of twinning. And when supersaturation is even higher, nucleation is fast and random.In an industrial continuous crystallization, the rapid growth of needle-like crystals is to be avoided as it leads to fragile crystals or needles, which can be partly broken or totally detached from the parent crystals especially along structural anisotropic axis corresponding to weaker chemical bonds, thus leading to slower growing faces. When an activated mechanism is involved such as a secondary surface nucleation, it is no longer possible to obtain a steady state. Therefore, the crystal number, size and habit vary significantly with time, leading to troubles in the downstream processing operations and to modifications of the final solid-specific properties.These results provide valuable information on the unique crystallization mechanisms of acicular crystals, and show that it is important to know these threshold and critical values when running a crystallizer in order to obtain easy-to-handle crystals.     

Stochastic complexity integral image based technique for fast video tracking

We propose a new method based on the minimization of the stochastic complexity for fast and efficient tracking adapted to video images with a static camera. The obtained criterion combines the advantages of background-subtraction-based techniques and those of using measures of similarities to a target model without requiring any tuning of a weighting parameter. It is then demonstrated that this approach can be implemented with a fast integral image technique to estimate the location and the rectangular shape of the target in a few milliseconds.     

Synchronization between optically injected semiconductor lasers on undamped relaxation oscillations

Seeding light from a laser into the cavity of a second one is a simple experiment largely encountered in optical domain (Stover, H.L., Steier, W.H.: Appl. Phys. Lett. 8, 91–93 (1966); Lang, R.: IEEE J. Quant. Elect. 18(6), 976–983 (1982)). With an unidirectional coupling, optical injection is a basic tool to study synchronization process between oscillators. The dynamics induced in this experiment have been extensively described, theoretically and experimentally (Simpson, T.B. et al.: Quant. Semiclassical Opt. 9(5), 765–784 (1997); Wieczorek S.: Opt. Commun. 172, 279–295 (1999); Blin, S.: Comptes Rendus de la Phys. 4(6), 687–699 (2003)) but mainly when the seeded light is a continuous wave (CW). In this paper, we describe the synchronization on an undamped relaxation regime. In order to study the degree of correlation between the two synchronized lasers (TL and RL), we use a cascade of two optical injections (Guignard, C.: Conference on Lasers and Electro Optics—the Europeen Quant. Electronics Conference (CLEO-EQEC), Munich (Germany), EC1M (2003)) thus three lasers: Master-transmitter laser (TL)-receiver laser (RL). The seeding by a field showing undamped relaxations can be directly compared with the optical injection by a CW signal, especially when the injected power and the detuning between the TL and RL frequencies are varied. Synchronization on undamped relaxation are shown to occur at values of the optical injected power and detuning, for which the RL is in the locked or wave-mixing regime when it is seeded by a CW. However, additional tongues of synchronization also exist at detuning equal to the relaxation oscillation frequency (ROF).     

Automated Parallel Synthesis of MADIX (Co)Polymers

An automated parallel synthetic approach has been developed for synthesizing polymer libraries by the Macromolecular Design via the Interchange of Xanthates (MADIX) process. The experimental set‐up, parallel polymerizations, characterization, and reproducibility tests are detailed. Examples of acrylic diblock copolymers synthesized in this way are given.

Automated MADIX polymerizations of BA in the presence of a X₁ ‐capped PEA.     

Comparison of the Phytochemical Variation of Non-Volatile Metabolites within Mother Tinctures of Arnica montana Prepared from Fresh and Dried Whole Plant Using UHPLC-HRMS Fingerprinting and Chemometric Analysis

Arnica montana L. has been recognized for centuries as an herbal remedy to treat wounds and promote healing. It also has a long tradition of use in homeopathy. Depending on its medicinal utilization, standardization regulations allow different manufacturing processes, implying different raw materials, such as the whole arnica plant in its fresh or dried state. In this study, an untargeted metabolomics approach with UHPLC-HRMS/MS was used to cross-compare the phytochemical composition of mother tinctures of A. montana that were prepared from either fresh whole plant (fMT) matter or from oven-dried whole plant (dMT) matter. The multivariate data analysis showed significant differences between fMT and dMT. The dereplication of the HRMS and MS/MS spectra of the more discriminant compounds led to annotated quinic acid, dicaffeoyl quinic acids, ethyl caffeate, thymol derivatives and dehydrophytosphingosine, which were increased in fMT, while Amadori rearrangement products (ARP) and methoxyoxaloyl-dicaffeoyl quinic acid esters were enhanced in dMT. Neither sesquiterpene lactones nor flavonoids were affected by the drying process. This is the first time that a sphingosine, ethyl caffeate and ARP are described in A. montana. Moreover, putative new natural products were detected as 10-hydroxy-8,9-epoxy-thymolisobutyrate and an oxidized proline fructose conjugate, for which isolation and full structure elucidation will be necessary to verify this finding.     

α-Hydroxylactams as Efficient Entries to Diversely Functionalized Ferrociphenols: Synthesis and Antiproliferative Activity Studies

The [ferrocene-ene-phenol] motif has been identified as the pharmacophore responsible for the anticancer activity of the family of ferrocene-based molecules coined ferrocifens, owing to its unique redox properties. The addition of imide entities to the historical ferrociphenol scaffold tremendously enhanced the cytotoxic activity of a large panel of cancer cell cultures and preliminary studies showed that the reduction of one of the carbonyl groups of the imide groups to the corresponding α-hydroxylactams only slightly affected the antiproliferative activity. As a continuation to these studies, we took advantage of the facile conversion of α-hydroxylactams to highly electrophilic N-acyliminium ions to graft various substituents to the imide motif of phthalimido ferrocidiphenol. Cell viability studies showed that the newly synthesized compounds showed diverse cytotoxic activities on two breast cancer cell lines, while only one compound was significantly less active on the non-tumorigenic cell line hTERT-RPE1.