Determination of the critical loads of shells by nondestructive methods

Two methods for determining the location of and load level to produce instability of compressed cylindrical shells are presented. The first relates the variation in the wall normal stiffness as a function of applied compressive force to the critical load. It uses the distribution of stiffness over the surface of the shell as a guide to buckle location. The second method associates the local dynamic mass with instability behavior. The test data presented show that either method will give excellent prediction capability from low-load-level data for shells of orthodox form. Neither method appears to apply to spirally stiffened shells. This is thought to be due to the fact that there is a substantial difference between the buckle pattern under axial compression and the imperfection shape induced by the normal displacement which is used to ascertain the wall stiffness and the dynamic mass.     

In vitro simulation of the chemical scenario of the action of an anti-thyroid drug: charge transfer interaction of thiazolidine-2-thione with iodine

Thiazolidine-2-thione (T2T) has been studied spectrophotometrically by UV–visible and IR spectra. The spectral studies have indicated that T2T has two tautomeric forms, namely thione and thiole forms, in addition to the dimeric thioamide complex existing as a hydrogen-bonded dimer of two thione forms. Interaction of the T2T as an electron donor with iodine as a typical σ-type acceptor has been studied spectrophotometrically. Electronic absorption spectra of the system T2T–I₂ in several organic solvents of different polarities have performed a clear charge transfer (CT) band in each spectrum. Formation constants (K_CT) and molar absorption coefficients (?_CT) and thermodynamic properties, ΔH, ΔS, and ΔG, of this system in various organic solvents were determined and discussed. The stoichiometric ratio of the T2T–I₂ system in solutions was found to be 1:1 T2T:I₂, whereas the elemental analysis of the prepared solid CT complex has illustrated the same stoichiometry. The obtained K_CT and ?_CT values have indicated that T2T is a donor of moderately strength capable of interacting with the iodine just to form the corresponding CT complex with an iodine molecule without further reducing of the iodine to either of the corresponding poly-iodide ions viz. I₃^?, I₅^?, etc. This action of spongy trapping of iodine simulates in vitro the chemical scenario of the anti-thyroid action of this compound.     

Free vibration of non-uniform column using DQM

Most of engineering problems are governed by a set of partial differential equations with proper boundary conditions. The present work is concerned with free vibration analysis of non-uniform column resting on elastic foundation and subjected to follower force. The used method of solution is the differential quadrature method (DQM). Formulation of the problem is introduced. The results obtained and compared with the exact solution and traditional numerical techniques such as finite element method. The parametric study is used to investigate the effect of column geometry on the natural frequencies, the mode shapes and the critical load.     

5 μm thick 3C-SiC layers grown on Ge-modified Si(100) substrates

The effect of the germanium coverage prior to the epitaxial growth of 5 μm thick 3C-SiC on Si(100) substrates were evaluated with Atomic Force Microscopy and μ-Raman spectroscopy. The 3C-SiC layers were grown by atmospheric pressure chemical vapor deposition via a special procedure leading to layers with compressive instead of tensile stress. The Ge amount was varied from 0 up to 2 ML. The obtained results showed that the residual stress inside the layers is shifted in the compressive direction; the crystalline quality is improved with the Ge introduction but on the account of the surface roughness. These results open the route for the use of Ge-modified Si(100) as a potential substrate in order to improve the heteroepitaxial growth of 3C-SiC on silicon substrates.     

Transmit diversity via oscillating-beam-pattern adaptive antennas: an evaluation using geometric-based stochastic circular-scenario channel modeling

Applying carefully-selected time-varying phases (delays) to array elements of an adaptive antenna, the beam pattern oscillates in a controlled manner. This creates a time varying channel with a controllable coherence time. With an adaptive antenna at the base station (BS) and a single omnidirectional antenna at the mobile, the controllable coherence time is used by the mobile to exploit time diversity and enhance performance. In this work, assuming an oscillating-beam-pattern antenna array at the BS, the channel is properly modeled and the coherence time is evaluated. A so-called geometric-based stochastic channel model is presented, assuming a circular coverage area, and the channel is simulated in an urban environment. We demonstrate the relationship between coherence time and the antenna array control parameters and show that seven-fold-diversity can be created via small beam pattern oscillation.     

Anticancer activity of lanthanum (III) and europium (III) 5-fluorouracil complexes on Caco-2 cell line

Lanthanide complexes are of increasing importance in cancer diagnosis and therapy. In the present study 1:1 and 1:3 solid complexes of La (III)–5-FU (5-fluorouracil) were prepared and characterized. In solution, the formation of 1:1 La (III) and Eu (III) complexes enabled the enhancement of 5-FU's effectiveness. Binding constants of the 1:1 complexes of both metals were estimated using spectrophotometry and HPLC with fluorescence detection methods. The thermodynamic parameters ΔG ^° , ΔH ^° and ΔS ^° were calculated using differential scanning calorimetry. Evaluation of the cytotoxic activity of the 1:1 La (III)- and Eu (III)–5-FU complexes was performed through two methodologies, trypan blue for cell viability where La (III)- and Eu (III)–5-FU complexes were found to have 52,000 and 80,000 dead cells, respectively, and via flow cytometric analysis to measure the apoptotic values, which were found to be 59.87 and 86.86% respectively.     

Structure investigation of mesalazine drug using thermal analyses,mass spectrometry,DFT calculations,and NBO analysis

Mesalazine (MZ) drug has been used for several decades as a primary treatment for inflammatory bowel diseases. The drug was investigated using thermal analysis (TA) measurements and electron impact mass spectral fragmentation at 70 and 15 eV of electron energy. The optimum molecular geometry and the total energy of the neutral and the positively charged MZ molecules were calculated by density functional theory method with 6-311++G(d,p) basis sets. Stability of the molecules arising from hyperconjugative interactions, charge delocalization, and the natural atomic charges has been analyzed using natural bond orbital analysis. In electron ionization mass spectrometry, the primary rupture is due to successive loss of H₂O (OH from carboxyl and H from phenolic OH of the ring) and CO of the acetyl group. Thermogravimetric results have revealed two stages of mass loss at 75.3 and 25.3 % in ranges 225–350 and 350–650 °C, respectively. The first one may be due to successive losses of different groups or molecules with fast rate of decomposition. A comparison between MS and TA helped in selection the proper pathway representing the fragmentation mechanism of this drug.     

An energy-aware forecasting-based framework using a novel moving coordinate scheme for sensor real-time communications

Wireless Networks - In order to save on the energy expended by a sensor node in its communications with the sink, forecasting-based frameworks have recently been proposed. Those frameworks...