Synthesis of 4-Benzidinyl Butyric Acid: A Key Intermediate for Antibodies Production Against Benzidin

a four-step synthesis of monoalkylated benzidin is reported for immunogen preparation against benzidin dye. Use of 10% H₂SO₄/ dioxan for N-Boc cleavage avoids the cyclisation of 4-benzidinyl butyric acid into the corresponding lactam observed with the classical TFA/ CH₂Cl₂ system.     

Missing boundary data recovery using Nash games: the Stokes system

We consider the Cauchy-Stokes problem. We use a new method based on Nash game theory to recover the missing velocity and normal stress on some inaccessible part of the boundary. This method is used with two different approaches. The first one is compared to a control type one. The numerical study attests that both approaches give accurate results. We compare these results with those of the energy-like minimization method.