Utility of N‐[4‐(N‐Substituted Sulfamoyl)Phenyl] Cyanothioformamides in the Synthesis of Heterocyclic Compounds

The novel cyanothioformamides 2a‐d were prepared by treatment of isothiocyanatosulfonamides 1a‐d with potassium cyanide at room temperature. Cyclocondensation of compounds 2b,c with phenyl isocyanate as electrophile furnished the corresponding imidazolidines 3a,b . The reactivity of compound 3a towards some nitrogen nucleophiles was investigated. Thus, the thiosemicarbazone 4 and imidazo[4,5‐b]quinoxaline 6 were synthesized by condensation of compound 3a with thiosemicarbazide and o‐phenylenediamine, respectively. Treatment of 3a with hydrochloric acid afforded compound 7 . Our investigation was extended to include the reactivity of cyanothioformamide 2 towards o‐aminophenol, anthranilic acid, and o‐phenylenediamine and yielded the corresponding heterocycles 9 , 11 and 13 derivatives, respectively. Structures of the synthesized compounds were established by their elemental analysis and spectral data.     

In situ assembled ZIF superstructures via an emulsion-free soft-templating approach

Assembling well-defined MOF superstructures remains challenging as it requires easily removable hard templates or readily available immiscible solutions for an emulsion-based soft-template approach. In this work, a single-step emulsion-free soft templating approach is reported to spontaneously prepare hollow ZIF-8 and ZIF-67 colloidosomes with no further purification. These superstructures can load different enzymes regardless of the size and charge with a high encapsulation efficiency of 99%. We envisage that this work will expand the repertoires of MOF superstructures by the judicious selection of precursors and the reaction medium.

An emulsion-free approach for the preparation of hollow ZIF-8 superstructures in a single step is established based on metal sulfate hydrates in methanol.     

A β-glucosidase from Sclerotinia sclerotiorum

The filamentous fungus Sclerotinia sclerotiorum, grown on a xylose medium, was found to excrete one β-glucosidase (β-glu x). The enzyme was purified to apparent homogeneity by ammonium sulfate precipitation, gel filtration, anion-exchange chromatography, and high-performance liquid chromatography (HPLC) gel filtration chromatography. Its molecular mass was estimated to be 130 kDa by HPLC gel filtration and 60 kDa by sodium dodecyl sulfate polyacrylamide gel electrophoresis, suggesting that β-glu x may be a homodimer. For p-nitrophenyl β-d-glucopyranoside hydrolysis, apparent K _m and V _max values were found to be 0.09 mM and 193 U/mg, respectively, while optimum temperature and pH were 55–60°C and pH 5.0, respectively. β-Glu x was strongly inhibited by Fe²⁺ and activated about 35% by Ca²⁺. β-Glu x possesses strong transglucosylation activity in comparison with commercially available β-glucosidases. The production rate of total glucooligosaccharides (GOSs) from 30% cellobiose at 50°C and pH 5.0 for 6 h with 0.6 U/mL of enzyme preparation was 80 g/L. It reached 105 g/L under the same conditions when using cellobiose at 350 g/L (1.023 M). Finally, GOS structure was determined by mass spectrometry and ¹³C nuclear magnetic resonance spectroscopy.     

Some spectroscopic aspects of electron transfer in ruthenium(II) polypyridyl complexes

The metal-to-ligand charge transfer (MLCT) absorption and emission properties of several ruthenium(II)-bipyridine am(m)ine complexes are compared. The Gaussian deconvolution of the spectra indicates that: (a) the emission MLCT bandwidths are smaller than the absorption bandwidths for the first components of the apparent vibronic progressions; (b) the emission bands decrease in energy and width when a polypyridyl is replaced by an am(m)ine. The observations can be interpreted in terms of a two state model and the perturbation theory-based treatment of the attenuation of the effective reorganizational energy, λ_r =^~ λ_r ^o(1- 4α² _DA), where λ_r ^o is the reorganizational energy corresponding to no mixing between the two electron transfer states and α_DA = (H_DA/E_DA) is the mixing coefficient. Both the solvent and molecular contributions to λ_r are attenuated. The MLCT excited state lifetimes also decrease with am(m)ine substitution, and the non-radiative decay rate constant at 77 K is roughly proportional to the number of am(m)ine moieties coordinated to the ruthenium center.     

Spectral and magnetic properties of phenylazo-6-aminouracil complexes

Complexes of Co(II), Ni(II) and Cu(II) with substituted phenylazo-6-aminouracils containing (-H, p-OH, p-CH(3), p-OCH(3) p-COOH) have been synthesized and characterized by elemental analysis, magnetic measurements and spectral measurements (IR, UV-Vis, ESR). Infrared spectra assigned the fundamental bands of the major groups, O-H, N-H, C-H, C=O, C=N, N=N, C-N and C-O (nu, delta and gamma modes of vibrations). The absence of nu(OH) and the appearance of nu(C=O) in the infrared spectra of the free ligands of 5-(p-tolyl and p-anisylazo)-6-aminouracil, assigned the keto structure, whereas in cases of 5-(phenyl, p-hydroxyphenyl and p-carboxyphenylazo)-6-aminouracil ligands, the data showed strong nu(OH) and nu(C=O) bands to assign keto-enol tautomerisms. The modes of interactions between the ligands and the metals were discussed, where oxygen and nitrogen atoms (of amino-amide groups) are involved in chelation. The azo group was not involved in chelation for all the prepared complexes except those of copper complexes derived from 5-(phenyl, p-tolyl, p-hydroxyphenyl and p-carboxyphenylazo)-6-aminouracils. The room temperature effective magnetic moment values, the Nujol mull spectra and ESR proved that all the prepared complexes were of octahedral geometry, except the nickel complex derived from 5-(phenylazo)-6-aminouracil and cobalt complex derived from 5-(p-carboxy-phenylazo)-6-aminouracil were square planar.     

KMo5O13 and KNb1.76Sb3.24O13

The title compounds, potassium pentamolybdenum oxide, KMo₅O₁₃, and potassium niobate antimonate or potassium niobium antimony oxide (1/1.76/3.24), KNb_1.76Sb_3.24O₁₃, were synthesized by solid‐state reactions and are isomorphous in space group Cmcm. The structure of the Mo complex has three unique Mo atoms and consists of MoO₆ octahedra sharing edges to form Mo₂O₆ pairs and Mo₃O₉ triplets, which, in turn, form layers by sharing corners. These layers are linked together in the [100] direction, yielding a three‐dimensional network similar to that of KSb₅O₁₃. This framework delimits interconnected tunnels, running approximately along the [110] and [10] directions, in which K⁺ ions are located. In the isomorphous KNb_1.76Sb_3.24O₁₃ structure, one of the Mo sites in KMo₅O₁₃ is replaced by Sb and the other two Mo sites have been replaced by Nb/Sb.     

Mathematical Analysis and Performance Evaluation of the Cell-Free mMIMO Networks Based on Cognitive Relays

Wireless Personal Communications - The cell-Free massive multiple input multiple output “mMIMO” networks can provide a satisfied performance for the fifth generation “5G”...     

2D and 3D image localization,compression and reconstruction using new hybrid moments

In this article, we will present a new set of hybrid polynomials and their corresponding moments, with a view to using them for the localization, compression and reconstruction of 2D and 3D images. These polynomials are formed from the Hahn and Krawtchouk polynomials. The process of calculating these is successfully stabilized using the modified recurrence relations with respect to the n order, the variable x and the symmetry property. The hybrid polynomial generation process is carried out in two forms: the first form contains the separable discrete orthogonal polynomials of Krawtchouk–Hahn (DKHP) and Hahn–Krawtchouk (DHKP). The latter are generated as the product of the discrete orthogonal Hahn and Krawtchouk polynomials, while the second form is the square equivalent of the first form, it consists of discrete squared Krawtchouk–Hahn polynomials (SKHP) and discrete polynomials of Hahn–Krawtchouk squared (SHKP). The experimental results clearly show the efficiency of hybrid moments based on hybrid polynomials in terms of localization property and computation time of 2D and 3D images compared to other types of moments; on the other hand, encouraging results have also been shown in terms of reconstruction quality and compression despite the superiority of classical polynomials.

     

Detection of Abnormal Activities from Various Signals Based on Statistical Analysis

We perceive big data with massive datasets of complex and variegated structures in the modern era. Such attributes formulate hindrances while analyzing and storing the data to generate apt aftermaths. Privacy and security are the colossal perturb in the domain space of extensive data analysis. In this paper, our foremost priority is the computing technologies that focus on big data, IoT (Internet of Things), Cloud Computing, Blockchain, and fog computing. Among these, Cloud Computing follows the role of providing on-demand services to their customers by optimizing the cost factor. AWS, Azure, Google Cloud are the major cloud providers today. Fog computing offers new insights into the extension of cloud computing systems by procuring services to the edges of the network. In collaboration with multiple technologies, the Internet of Things takes this into effect, which solves the labyrinth of dealing with advanced services considering its significance in varied application domains. The Blockchain is a dataset that entertains many applications ranging from the fields of crypto-currency to smart contracts. The prospect of this research paper is to present the critical analysis and review it under the umbrella of existing extensive data systems. In this paper, we attend to critics' reviews and address the existing threats to the security of extensive data systems. Moreover, we scrutinize the security attacks on computing systems based upon Cloud, Blockchain, IoT, and fog. This paper lucidly illustrates the different threat behaviour and their impacts on complementary computational technologies. The authors have mooted a precise analysis of cloud-based technologies and discussed their defense mechanism and the security issues of mobile healthcare.