非对称型外差激光探针

本文描述用于检测微振动的非对称型外差激光探针系统及实验结果。实验数据表明,系统检测灵敏度为1×10~(-4)nm/(Hz)~1/2将本系统用于检测薄膜电路在交变电热下的微振动以及表面波聚焦换能器的辐射声场分布,得到满意的结果。     

养胃增液汤联合双歧四联活菌片治疗小儿 厌食症对患儿胃肠道激素水平的影响

摘 要:目的 探究养胃增液汤联合双歧四联活菌片治疗厌食症患儿对其胃肠道激素水平的影响。方法 收集2021年4月至2022年4月我院接纳的厌食症患儿110例,随机分为对照组:55例,年龄2~10岁,平均（6.02±1.09）岁,给予双歧四联活菌片,持续治疗4周。治疗组:55例,年龄2~10岁,平均（6.02±1.09)岁,给予双歧四联活菌片+养胃增液汤治疗,持续治疗4周,评估临床疗效,记录治疗前、治疗后两组患儿中医症状积分、体质量、日摄食量,采集患儿肘静脉血测量血清胃肠道激素水平,统计给药期间患儿不良反应。结果 治疗组总有效率显著高于对照组（P＜0.05）;治疗后治疗组体质量、日摄食量显著高于对照组（P＜0.05）;治疗后治疗组主症积分、次症积分均显著低于对照组（P＜0.05）;治疗后治疗组血清胃动素（MTL）、胃泌素（GAS）水平显著高于对照组,生长抑素（SS）水平显著低于对照组（P＜0.05）;对照组与治疗组不良反应发生率无显著差异（P＞0.05）。结论 养胃增液汤联合双歧四联活菌片治疗小儿厌食症可显著改善患儿胃肠道激素水平,缓解临床症状,提升临床疗效,且联合给药未见明显增毒现象。     

HIV蛋白酶多肽抑制剂的理论研究

艾滋病病毒的发现距今已有二十多年的历史了.它仍然以很快的速度在全球范围速蔓延.研发抗艾滋病药物是当代药学的重大课题之一.在以往研究的基础上,我们利用分子叠合和分子对接这两种分子模拟手段,把从PDB数据库中得到的与HIV蛋白酶结合的12个肽类分子和已经上市的抗艾滋病的药物Saquinavir做比较.根据结构相同或相近的分子具有相同的活性原理,运用分子叠合初部判断分子活性,特别是药效团的特征比对揭示了分子活性的原因,为进一步的药物设计奠定了良好的基础.进而采用分子对接的分子模拟方法对这12个肽类分子的活性构象进行了深入的分析,预测出了这12个分子对HIV病毒蛋白酶的不同抑制作用.研究发现:P01、P05、P09、P12可能与已知药物Saquinavir在与HIV蛋白酶结合时具有相似的活性,其中P9的活性最强,有望成为抗HIV药物的理想前体,为下一步的HIV药物的设计研究提供了理论依据.     

Microblaze软核处理器在惯测数据采集中的应用

为达到产品小型化要求，降低开发难度，采用Xilinx公司最新７系列内置Microblaze软核的FPGA芯片以实现数据采集，通过在惯测数据采集上应用的实际项目，详细说明了该类 FPGA芯片的Microblaze软核开发流程，包括应用系统的硬件 架构设计、在最新Vivado开发环境下的软核硬件平台的设计、整体软件的设计等，经过测试和对比，实验的结果充分说明Microblaze软核能够代替同类CPU芯片实现惯测产品的数据采集及处理，并具有其灵活高效的特性，在相近的应用场合中展现出独特的优势。     

cdma 1x终端测试

本文主要介绍了目前行业内对cdma 1x终端的测试要求.     

山西典型高铝煤灰熔融及黏温特性改性实验研究

以山西典型高铝煤为研究对象,研究了工业助熔剂石灰石、黏土以及两者的复合助熔剂对其灰熔融特性及黏温特性的影响。结果表明,随着助熔剂含量的增加,煤灰熔融流动温度下降;石灰石的助熔效果优于黏土,复合助熔剂效果优于单一助熔剂。添加石灰石使灰渣临界黏度温度tcv显著降低,添加黏土使其渣型向玻璃渣转变,复合助熔剂较单一助熔剂存在显著协同作用,即能同时实现tcv的降低和渣型的有利转变。对山西典型高铝煤两渡煤,在复合助熔剂添加量为4%(2%石灰石+2%黏土)时,不仅其渣型向玻璃渣转变,且tcv较单独添加石灰石(2%)降低133℃,较单独添加黏土(6%)降低222℃。矿物质分析结果证实了助熔剂的助熔原理。添加复合助熔剂改性的山西高铝煤可达到工业气流床气化对煤种的要求。     

添加剂对高碱煤钠迁移和灰分烧结温度的影响

选取三种不同的添加剂（高岭土、SiO₂和Al₂O₃）,研究它们对高碱准东煤钠迁移和灰分烧结温度的影响,并且添加比例为1%-5%。结果表明,三种添加剂的钠捕集效率依次为：高岭土 > SiO₂ > Al₂O₃。钠捕集效率随着添加比例的增加而升高,但受温度影响比较复杂。高岭土的钠捕集效率在600-1000℃先增加后减小,并在900℃达到最大值,其余两种随温度的升高均减小。准东煤灰的烧结温度为803℃,添加高岭土后,烧结温度随添加比例的增加先降低后上升。当添加比例为3%时,因为钙长石和钙黄长石的低温共熔反应而达到最小值。SiO₂的添加比例为5%时,由于透辉石的生成和SiO₂本身的"骨架"作用,烧结温度迅速升高到879℃。Al₂O₃对烧结温度的影响最小。     

An investigation of the mode of sorption of inositol hexaphosphate to goethite

Adsorption of inositol hexaphosphate (IP(6)) on goethite has been studied as a function of pH and concentration, and by use of Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy (ATR-FTIR). While adsorption was highest at low pH, a significant amount remained adsorbed above pH 10 where, in the absence of IP(6), the surface is expected to have a net negative charge. The adsorption isotherm at pH 5.5 indicated strong binding to the surface with each adsorbed species occupying about 2.5 nm(2). ATR-FTIR spectra of IP(6) solutions in the pH range from 2 to 12 were fitted with a single set of IR bands which were assigned primarily by analogy with phosphate spectra. From its variation in intensity with pH the band at 1040 cm(-1) was assigned to the effect of hydrogen bonding on the PO vibration. No additional bands were required to fit the spectra of IP(6) adsorbed to goethite, indicating that adsorption occurs by outer-sphere complexation in this system. At all pH values studied the band associated with hydrogen bonding was more intense for the adsorbed species than in solution at the corresponding pH indicating that hydrogen bonding plays an important role in binding IP(6) to goethite.     

Adsorption behavior of the (+/-)-Tröger's base enantiomers in the phase system of a silica-based packing coated with amylose tri(3,5-dimethyl carbamate) and 2-propanol and molecular modeling interpretation

The binary adsorption isotherms of the enantiomers of Tr?ger's base in the phase system made of Chiral Technologies ChiralPak AD [a silica-based packing coated with amylose tri(3,5-dimethyl carbamate)] as the chiral stationary phase (CSP) and 2-propanol as the mobile phase were measured by the perturbation method. The more retained enantiomer exhibits a S-shaped adsorption isotherm with a clear inflection point, the concentration of the less retained enantiomer having practically no competitive influence on this isotherm: In the entire range of concentrations studied, dq2/dC1 approximately 0. By contrast, the less retained enantiomer has a Langmuir adsorption isotherm when pure. At constant mobile phase concentrations, however, its equilibrium concentration in the adsorbed phase increases with increasing concentration of the more retained enantiomer and dq1/dC2 > 0. This cooperative adsorption behavior, opposed to the classical competitive behavior, is exceedingly rare but was clearly demonstrated in this case. Two adsorption isotherm equations that account for these physical observations were derived. They are based on the formation of an adsorbed multi-layer, as suggested by the isotherm data. The excellent agreement between the experimental overloaded elution profiles of binary mixtures and the profiles calculated with the equilibrium-dispersive model validates this binary isotherm model. The adsorption energies calculated by molecular mechanics (MM) and by molecular dynamics (MD) indicate that the chiral recognition arising from the different interactions between the functional groups of the CSP and the molecules of the Tr?ger's base enantiomers are mainly driven by their Van der Waals interactions. The MD data suggest that the interactions of the (-)-Tr?ger's base with the CSP are more favored by 8+/-(5) kJ/mol than those of (+)-Tr?ger's base. This difference seems to be a contributing factor to the increased retention of the - enantiomer on this chromatographic system. The modeling of the data also indicates that both enantiomers can form high stoichiometry complexes while binding onto the stationary phase, in agreement with the results of the equilibrium isotherm studies.