全文获取类型
收费全文 | 40062篇 |
免费 | 4828篇 |
国内免费 | 3851篇 |
专业分类
化学 | 21450篇 |
晶体学 | 371篇 |
力学 | 1436篇 |
综合类 | 234篇 |
数学 | 3610篇 |
物理学 | 9321篇 |
无线电 | 12319篇 |
出版年
2024年 | 82篇 |
2023年 | 735篇 |
2022年 | 889篇 |
2021年 | 1240篇 |
2020年 | 1234篇 |
2019年 | 1235篇 |
2018年 | 1062篇 |
2017年 | 1072篇 |
2016年 | 1453篇 |
2015年 | 1577篇 |
2014年 | 1870篇 |
2013年 | 2466篇 |
2012年 | 2975篇 |
2011年 | 3176篇 |
2010年 | 2377篇 |
2009年 | 2410篇 |
2008年 | 2638篇 |
2007年 | 2499篇 |
2006年 | 2260篇 |
2005年 | 1984篇 |
2004年 | 1560篇 |
2003年 | 1305篇 |
2002年 | 1259篇 |
2001年 | 1053篇 |
2000年 | 904篇 |
1999年 | 843篇 |
1998年 | 732篇 |
1997年 | 671篇 |
1996年 | 688篇 |
1995年 | 574篇 |
1994年 | 528篇 |
1993年 | 480篇 |
1992年 | 446篇 |
1991年 | 377篇 |
1990年 | 327篇 |
1989年 | 242篇 |
1988年 | 207篇 |
1987年 | 144篇 |
1986年 | 164篇 |
1985年 | 176篇 |
1984年 | 117篇 |
1983年 | 75篇 |
1982年 | 81篇 |
1981年 | 59篇 |
1980年 | 58篇 |
1979年 | 62篇 |
1978年 | 49篇 |
1976年 | 46篇 |
1974年 | 48篇 |
1973年 | 47篇 |
排序方式: 共有10000条查询结果,搜索用时 46 毫秒
941.
Removal of Endotoxin from Human Serum Albumin Solutions by Hydrophobic and Cationic Charged Membrane 总被引:1,自引:0,他引:1
Removal of end6toxin from medicine injection is very important, becauseendotoxin withpotential biological activity causes pyrogenic and shock reactions in' mammals-'on...intravenous injection even as law as "an6gram amounts. Endotoxin, a constituent ofpotential contaminant of physiological fluids and aqueous solutions 'and very stable atextreme temperature and PH values. For removing endotoxin from solutions ofbiomolecules, such as HSA, adsorption techniques are usedl.' Many methods forendot… 相似文献
942.
The m6A‐RNA modification is a dynamic and reversible process, which has emerged as a new RNA code for the regulation of gene expression. The functional network of methyltransferases (writers), demethylases (erasers), and binding proteins (readers) modulate the level of m6A modification. Dysfunction of RNA methylation has been associated with various fundamental biological processes and human diseases. Herein, we briefly introduce an understanding‐enabled manipulation on m6A‐RNA modification with an emphasis on the use of small‐molecule intervention. 相似文献
943.
The atomic absorption inhibition titration of phosphates was studied for two types of burner. Dependence on gas Flow-rates was observed. The method with a pre-mix burner was employed to determine phosphate in surface and waste waters. The results are compared with those by the standard method. The proposed method was found to be rapid, simple and accurate. 相似文献
944.
The formal synthesis of antimicrobial diterpene udoteatrial hydrate (1) is described in nine steps. Diol 6 used as starting material. The key intermediate 4 was obtained from bicyclic ketone 5 via the key Norrish type I reaction. 相似文献
945.
Ding L Liu W Wang W Glinka CJ Worcester DL Yang L Huang HW 《Langmuir : the ACS journal of surfaces and colloids》2004,20(21):9262-9269
A neutron diffraction method applicable to nonlamellar phases of substrate-supported lipid membranes is described and validated. When prepared on a flat substrate, the resulting nonlamellar phases have layered symmetry which provides some advantages over powder diffraction for detailed structure determination. This approach recently led to the detection of a rhombohedral phase and a distorted hexagonal phase of lipids. Here the determination of intensity and phase information for such phases is demonstrated by application to the hexagonal phase of diphytanoyl phosphatidylcholine (DPhPC). The hexagonal symmetry is used to verify the data reduction procedure for the intensities of the diffraction peaks. Diffraction intensities measured while varying the D2O/H2O ratio in the relative humidity was used to solve the phase problem. The neutron scattering length density distribution of the hexagonal phase was constructed and analyzed to elucidate the packing of the lipid molecules. The structure of DPhPC in the hexagonal phase is of interest in connection with its stalk structure in the rhombohedral phase. We also found that the incorporation of tetradecane into the DPhPC hexagonal phase is limited, similar to the case for dioleoyl phosphatidylethanolamine. 相似文献
946.
Four new lignans, 3',4'-O,O-demethylenehinokinin (1), chamalignolide (2), 8'beta-hydroxyhinokinin (3) and 7beta,8beta-epoxyzuonin A (4), as well as (-)-hinokinin (5), and (-)-zuonin A (6), were isolated from the heartwood of Chamaecyparis obtusa var. formosana. The structures of these lignans were unambiguously determined by spectroscopic methods. And the absolute configuration of 1 was elucidated with a circular dichroism (CD) spectrum. 相似文献
947.
Huang HS Chiou JF Chiu HF Hwang JM Lin PY Tao CW Yeh PF Jeng WR 《Chemical & pharmaceutical bulletin》2002,50(11):1491-1494
The synthesis of a series of anthraquinone moieties bearing symmetrical sulfur-linked substituents in the 1 and 5 positions is described. These compounds were evaluated for their ability to inhibit the growth of suspended rat glioma C6 cells and human hepatoma G2 cells, respectively. In addition, the redox property of the compounds was determined based on the inhibition of lipid peroxidation in model membranes. Compounds 2a and 2h in this series compared favorably and exhibited the most potent cytotoxicity (0.02, 0.05 microM) against C6 cells in the XTT colorimetric assay. As far as redox properties are concerned, all bis-thio-anthraquinones show potential lipid peroxidation in model membranes very close to that of mitoxantrone (MX), and 2a, 2d, 2e, 2i, 2j, and 2k have more potential than that of MX. The lack of cytotoxicity of compound 2i cannot be related to lipid peroxidation, but the steric and electronic properties of the side-chain substituent maybe impair effective recognition of the cleavable complex. In contrast to MX, 2a and 2h are cytotoxic in rat glioma C6 cells and do not enhance lipid peroxidation in model membranes. 相似文献
948.
Michael F. Cunningham Karine Tortosa Marcus Lin Barkev Keoshkerian Michael K. Georges 《Journal of polymer science. Part A, Polymer chemistry》2002,40(16):2828-2841
The rate‐accelerating effects of camphorsulfonic acid (CSA) on nitroxide‐mediated styrene miniemulsion polymerization were studied. Polymerizations were initiated with benzoyl peroxide (BPO) as an initiator and mediated with either 2,2,6,6‐tetramethylpiperidinyloxy (TEMPO) or 4‐hydroxy‐2,2,6,6‐tetramethylpiperidinyloxy (OH‐TEMPO). Although CSA has been used to accelerate the rate in bulk nitroxide‐mediated polymerizations, it has not been well studied in emulsion/miniemulsion. With dispersed systems, the effectiveness of CSA is likely to be affected by partitioning between the aqueous and organic phases. In styrene miniemulsion experiments performed over a range of conditions, the effect of adding CSA varied from negligible to significantly increasing the final conversion and molecular weight, depending on the nitroxide:BPO ratio. At a ratio of nitroxide:BPO = 1.7, the effect of CSA addition is small, whereas the final conversion and molecular weight are dramatically enhanced by CSA addition when the nitroxide:BPO ratio is 3.6. CSA is most effective in enhancing the rate and molecular weight when the initial free‐nitroxide concentration is higher. The magnitude of the rate and molecular weight enhancement was similar for TEMPO and OH‐TEMPO despite their differences in water solubility. © 2002 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 40: 2828–2841, 2002 相似文献
949.
本文提出一种新型的离子色谱方法,采用恒电流电场代替机械泵输送离子,研制出体积小、重量轻、成本低、易操作的电迁移微离子色谱仪,并检测了几种常见的阴离子,Cl~-、Br~-、NO_2~-的检测极限为10~(-11)~10~(-12)mol,峰高和保留时间重现性相对标准偏差均<3%,进样量与峰高的线性关系良好。 相似文献
950.
S. C. Lin B. J. Bulkin E. M. Pearce 《Journal of polymer science. Part A, Polymer chemistry》1979,17(10):3121-3148
Three cured epoxy resins were investigated under various degradation conditions by Fourier transform infrared (FTIR) spectroscopy for measurement. The epoxy resins were the diglyadyl ethers of bisphenol A (DGEBA), phenolphthalein (DGEPP), and 9,9-bis(4-hydroxyphenyl)fluorene (DGEBF). The thermal stability order of functional groups that incurred DGEBA was total methyl group ~ total benzene ring > methylene > p-phenylene > ether linkage > isopropylidene. The oxidative thermal and photodegradation processes were found to be related to the classical autocatalytical oxidation of aliphatic hydrocarbon segments. The Wieland rearrangement, Norrish-type reaction, Claisen rearrangement, and other possible degradation mechanisms were suggested by the data. 相似文献