快速检测心型脂肪酸结合蛋白的荧光免疫微流体测试卡

研制出一种以时间分辨荧光微球作为标记,自驱动快速检测H-FABP的荧光免疫微流体测试卡.利用激光切割法在双面胶上简便、快速地切割出所设计的微通道结构,并采用激光切割法制作出聚甲基丙烯酸甲酯(PMMA)测试卡底板及上盖.使用提拉涂膜的方法在PMMA底板表面修饰马来酸酐官能团,有效地解决了捕获抗体在PMMA表面的固定问题.使用等离子体处理测试卡上盖改善其亲水性,使液体能够在微通道内自行流动.使用此测试卡可以实现对心型脂肪酸结合蛋白(H-FABP)的快速检测,线性检测范围为0.5～ 100 ng/mL,检出限为0.1 ng/mL(S/N=3),检测时间少于10 min,批内相对标准偏差(RSD) ＜10％,批间RSD＜15％.本方法具有灵敏度高、检测时间短、结果准确等优点,可以满足临床检测的需求,具有良好的应用前景.     

Study on sol–gel-modified ammonium polyphosphate and its application in the flame-retardant polyurethane composites

Journal of Sol-Gel Science and Technology - In this study, organic–inorganic-modified ammonium polyphosphate (APP) flame retardant (FR) was prepared by a sol–gel method that used...     

Regulation of Electrocatalytic Activity by Local Microstructure: Focusing on the Catalytic Active Zone

Traditional regulation methods of active sites have successfully optimized the performance of electrocatalysts, but seem unable to achieve further breakthrough in the catalytic activity. Unlike the conventional viewpoint of focusing on single active site, the concept of local microstructure active zone is more comprehensive and new methods to regulate the reaction zone for electrocatalytic reactions are developed accordingly. The local microstructure active zone refers to the zone with high catalytic activity formed by the interaction between active atoms and neighboring coordination atoms as well as the surrounding environment. Instead of the traditional single active atom site, the active zone is more suitable for the actual electrochemical reaction process. According to this concept, the activity of electrocatalysts can be coordinated by multiple active atoms. This strategy is beneficial for understanding the relationship between material, structure, and catalysis, which realizes the design and synthesis of high-performance electrocatalysts. This review provides the research progress of this strategy for electrocatalytic reactions, with emphasis on their applications in oxygen evolution reaction, urea oxidation reaction, and carbon dioxide reduction.     

Synthesis of Spirocycles via Ni-Catalyzed Intramolecular Coupling of Thioesters and Olefins

A nickel-catalyzed intramolecular coupling of thioesters and olefins has been developed for the efficient synthesis of spirocycles, a privileged scaffold commonly found in natural products. This transformation is characterized by the simultaneous transfer of both acyl and thiol moieties to the alkene, with the suppression of decarbonylation and β-hydrogen elimination. Initial mechanistic investigations are consistent with an oxidative addition/olefin insertion/reductive elimination mechanism. The incorporated methylene sulfide substituent can undergo a variety of further reactions to increase molecular diversity and complexity. These results demonstrate that thioester derivatives can be used as powerful building blocks for the assembly of complex scaffolds.     

基于案例教学法的物理化学课程教学改革探索与实践

Case teaching method is adopted to reform physical chemistry teaching to mobilize students' learning enthusiasm, activate classroom atmosphere and help students to understand nonfigurative and difficult basic concepts and principles. Theory is combined with practice, and a lot of cases from daily life, industrial and agricultural production together with scientific research are introduced into the whole teaching process of physical chemistry. Thus, the teaching effect is greatly improved.     

漳州广电模数整体平移方案初探

分析了基于DVB-C的有线数字电视前端传输平台的组成及各种设备的选型等,最后简单介绍了漳州广电模数整体平移以及平移时应注意的一些问题.     

A new automatic exposure algorithm for video cameras using luminance histogram

Automatic exposure (AE) is one of the indispensable functions of modern video cameras. According to the attention mechanism of human visual systems, peak regions in luminance histogram correspond to the region of no interest in an image. Based on this assumption, a new AE algorithm using the luminance histogram of an image is proposed in this paper. The algorithm finds the first two largest peak regions in the histogram and calculates the mean weighted luminance (MWL) of the entire image by weighting the luminance of pixels inside the two peak regions. The MWL is then used to control the exposure of video cameras. The weight of pixel luminance is decided by a set of quadratic curves, and the parameters of the quadratic curves are affected by the brightness of the image background. Fuzzy logic is also applied to optimize the practical AE systems. Results show that the proposed algorithm gives efficient exposure control over various scene tests.     

Result of search for low velocity exotic particles

The L3+C experiment, taking advantage of the L3 muon magnetic spectrometer, measured the spatial tracks of charged cosmic ray particles to obtain rigidity as well as velocity. One possible low velocity exotic particle is observed. The existing uncertainties are discussed, and the flux upper limit of the low velocity exotic particles from this observation is deduced based on the assumption of a null observation. The result is 6.2×10-10 cm-2.s-1.sr-1 at 90% confidence level in the velocity range from 0.04c to 0.5c.