Study of the stresses associated with the hot orientation of certain carbon-chain fibers

The process of hot orientation of Khlorin, polyacrylonitrile, and polypropylene fibers is investigated; the stresses associated with this process are determined. The possibility of determining the actual temperature in the orientation zone is demonstrated. The effect of the mobility of the macromolecules on the stresses is considered.Tashkent Institute of the Textile Industry. Translated from Mekhanika Polimerov, No. 2, pp. 372–374, March–April, 1972.     

Controlling the parameters of short-wavelength radiation pulses using the interference of transitions to a continuum

Specific features of the propagation of light pulses with frequency lying in the range of autoionization resonances of the medium are analyzed. It is shown that the interference nature of the autoionization spectra makes it possible to combine a strong frequency dispersion of the refractive index with small absorption when the radiation frequency approaches the spectral range of the "transparency window" of an isolated resonance or of a series of overlapped autoionization resonances. This allows one to control the time delay of the pulses and their group velocity. Depending on the parameters of the medium, the pulse group velocity may be maximally reduced by a factor of 10⁴–10⁵.     

Enhanced nigrostriatal neuron-specific,long-term expression by using neural-specific promoters in combination with targeted gene transfer by modified helper virus-free HSV-1 vector particles

Background  

Direct gene transfer into neurons has potential for developing gene therapy treatments for specific neurological conditions, and for elucidating neuronal physiology. Due to the complex cellular composition of specific brain areas, neuronal type-specific recombinant gene expression is required for many potential applications of neuronal gene transfer. One approach is to target gene transfer to a specific type of neuron. We developed modified Herpes Simplex Virus (HSV-1) particles that contain chimeric glycoprotein C (gC) – glial cell line-derived neurotrophic factor (GDNF) or brain-derived neurotrophic factor (BDNF) proteins. HSV-1 vector particles containing either gC – GDNF or gC – BDNF target gene transfer to nigrostriatal neurons, which contain specific receptors for GDNF or BDNF. A second approach to achieve neuronal type-specific expression is to use a cell type-specific promoter, and we have used the tyrosine hydroxylase (TH) promoter to restrict expression to catecholaminergic neurons or a modified neurofilament heavy gene promoter to restrict expression to neurons, and both of these promoters support long-term expression from HSV-1 vectors. To both improve nigrostriatal-neuron specific expression, and to establish that targeted gene transfer can be followed by long-term expression, we performed targeted gene transfer with vectors that support long-term, neuronal-specific expression.     

Probe studies of silicon p-n junctions

The results of single-probe studies of thick and thin silicon p-n junctions are described. The electric fields in a diode with a p⁺-n junction and in a stabilitron with a p-n junction in the forward and reverse directions are studied. Measurements are made at various currents and temperatures. The p-n junctions are analyzed on the basis of the probe measurements.     

Oxacalixarenes and oxacyclophanes containing 1,8-naphthyridines: a new class of molecular tweezers with concave-surface functionality

The first examples of oxacalix[4]arenes and [1(4)]oxacyclophanes bearing 1,8-naphthyridine units are reported, and these systems function as molecular tweezers containing inner-cavity hydrogen bond acceptors.     

He superfluidity in the presence of aerogel

Aerogels introduce disorder into the p-wave-paired superfluid ³He and suppress T_c. Quantifiable (by small angle X-ray scattering) differences in the long-range structure of two identical density aerogels are primarily responsible for their different transition temperatures. We also demonstrate that alteration of the short-range correlations by the addition of ⁴He does not strongly affect T_c. Acoustic measurements of the fast and slow modes of ³He in aerogel are described. These can be used to explore the superfluid component. We also outline future prospects.     

Strong Microheterogeneity in Novel Deep Eutectic Solvents

With the increasing application of template assisted syntheses in deep eutectic solvents and successful application of hydrophobic deep eutectic solvents in extraction processes, where microheterogeneity plays a major role, suggestions for novel deep eutectic solvents which exhibit strong microheterogeneity are desirable. Therefore, classical molecular dynamics simulations were carried out on deep eutectic solvent systems constructed of choline chloride and some of its derivatives mixed with ethylene glycol in a molar composition of 1 : 2 since this is the optimal parent composition. The derivatives consisted of a series of elongated alkyl side chains and elongated alcohol side chains. Of these series only choline chloride ethylene glycol has been investigated experimentally, the other systems are suggested and theoretically investigated as possible target for synthesis. Our domain analysis supported by the clear distinction of polar and nonpolar parts from the electrostatic potentials reveals that strong microheterogeneity within these novel hypothetical deep eutectic solvents exists. Rather stretched than crumbled side chains maximize possible interaction sites for both polar and nonpolar parts which make the suggested compounds valuable objectives for experiments in order to exploit the microheterogeneity in deep eutectic solvents.