Compositions and Biological Activities of Pomegranate Peel Polyphenols Extracted by Different Solvents

Pomegranate peel extract (PPE), which is abundant in polyphenols, holds immerse prospects for the treatment of airway infection. In this study, water and ethanol of 30%, 50%, and 80% were used to prepare PPE. A total of 18 phenols belonging to 8 categories of polyphenols were identified in PPE by HPLC-MS/MS. The PPE from the four extraction solvents possessed different antioxidant, antibacterial, and anti-inflammatory activities. Principal component analysis revealed that though total flavonoids (TFs), total polyphenols (TPs), and total tannins (TTs) were responsible for the reducing power of PPE, only TFs contributed to the effect of PPE in inhibiting lipid membrane peroxidation. TPs, TTs, and punicalagin were positively correlated with the antibacterial strength against S. aureus while TTs alone contributed to the inhibition of methicillin-resistant S. aureus, implying the crucial role of TT in suppressing bacteria. Meanwhile, TTs was associated with the prevention of IL-6 release. The PPE with higher contents of TPs, TTs, and punicalagin had a weaker capacity to decrease nitric oxide secretion. PPE of 30% ethanol gained the highest integrated score due to its stronger antioxidant, antibacterial, and anti-inflammatory activities. It is a suitable candidate for the therapy of respiratory tract infection.     

Antibacterial Activity of Aureonuclemycin Produced by Streptomyces aureus Strain SPRI-371

Actinomycetes play a vital role as one of the most important natural resources for both pharmaceutical and agricultural applications. The actinomycete strain SPRI-371, isolated from soil collected in Jiangsu province, China, was classified as Streptomyces aureus based on its morphological, physiological, biochemical and molecular biological characteristics. Its bacterial activity metabolites were identified as aureonuclemycin (ANM), belonging to adenosine derivatives with the molecular formula C₁₆H₁₉N₅O₉ for ANM A and C₁₀H₁₃N₅O₃ for ANM B. Simultaneously, the industrial fermentation process of a mutated S. aureus strain SPRI-371 was optimized in a 20 m³ fermentation tank, featuring a rotation speed of 170 rpm, a pressure of 0.05 MPa, an inoculum age of 36–40 h and a dissolved oxygen level maintained at 1–30% within 40–80 h and at >60% in the later period, resulting in an ANM yield of >3700 mg/L. In the industrial separation of fermentation broth, the sulfuric acid solution was selected to adjust pH and 4# resin was used for adsorption. Then, it was resolved with 20% ethanol solution and concentrated in a vacuum (60–65 °C), with excellent results. Antibacterial experiments showed that ANM was less active or inactive against Xanthomonas oryzae pv. oryzae, Xanthomonas citri subsp. citri and Xanthomonas oryzae pv. oryzicola and most bacteria, yeast and fungi in vitro. However, in vivo experiments showed that ANM exhibited extremely significant protective and therapeutic activity against diseases caused by X. oryzae pv. oryzae and X. oryzae pv. oryzicola in rice and X. citri in oranges and lemons. In field trials, ANM A 150 gai/ha + ANM B 75 gai/ha exhibited excellent therapeutic activity against rice bacterial leaf blight, citrus canker and rice bacterial leaf streak. Furthermore, as the dosage and production cost of ANM are lower than those of commercial drugs, it has good application prospects.     

Asymmetric synthesis of chromanone lactones via vinylogous conjugate addition of butenolide to 2-ester chromones

Chiral chromanone lactones are a class of natural products with important biological activity. We report a direct diastereo- and enantioselective vinylogous conjugate addition of butenolide to 2-ester substituted chromones. The transformation proceeded well in the presence of as low as 1 mol% of a chiral N,N′-dioxide/Sc^III complex, 3 Å MS and a catalytic amount of hexafluoroisopropanol (HFIP). The scope of Michael acceptors includes a variety of substituted chromones at different positions, and the desired chromanone lactones upon reduction are afforded in good yield and diastereoselectivity, and excellent enantioselectivity (up to 99% ee). The strategy could be used in the concise synthesis of blennolide C and gonytolide A, C and G.

We report a direct, diastero- and enantioselective vinylogous 1,4-addition of butanolide to 2-ester chromones. A chiral Sc^III complex enabled the reaction to proceed smoothly to give a variety of chraomanone lactones.     

基于海洋背景红外图像的仿真系统研究

简要介绍了一种简便的基于海洋背景的红外仿真系统的设计和组成,阐述了各个模块的功能以及模块之间的联系。在实际存储红外图像素材基础上,通过直接添加模板图像,接着通过后续的处理模块来实现较好的模拟海洋红外图像中的目标的目的。从最后的结果可以看到这是一个简便有效的仿真系统。     

分布式实时数据库在输变电系统中的应用

本论文主要对分布式实时数据在输变电系统中各项事务管理和数据汇总处理等应用进行阐述.首先介绍了分布式实时数据库及其特点,接着,详细介绍了分布式实时数据库在输变电系统中的应用.分布式实时数据库的建立可以实现对国网山西省电力公司检修公司所有事务的处理和对所运营的各地区的变电站实时数据进行汇总和处理,同时为智能变电站网络管理系统的建立提供知识库数据和专家经验.为变电站的联网运行奠定基础.     

非制冷色散式成像光谱仪辐射传递模型

根据接收信号信噪比,研究了基于非制冷微测辐射热计阵列构造色散式成像光谱仪的可行性.综合考虑目标红外辐射特性、大气传输透过率、仪器接收孔径、色散式光谱仪辐射传递特性、红外阵列探测器参数、数据链传输等环节,建立了完善的色散式长波红外成像光谱仪辐射能量传递模型.选用典型地物红外发射率数据,非制冷微测辐射热计红外焦平面阵列参数,利用低分辨率大气辐射传输计算软件LOWTRAN生成大气红外透过率曲线,依据传递模型,计算了以非制冷微测辐射热计阵列为探测器的色散式长波红外成像光谱仪可达到的光谱分辨率,验证了依据非制冷红外探测器构建小型红外成像光谱遥感器的潜力.     

电源处理单元配置方案可靠性比较及选择

电推进技术是航天推进技术一个重要的发展方向.针对新一代通信卫星平台电推进系统的需求,对用于电推进系统的电源处理单元的4种备选配置方案做了介绍,并对每种方案的可靠性进行了计算.通过可靠性指标对比和对配置方案的分析,为方案优选提供了一些依据.     

8～12μm波段折/反/衍混合坦克扫描物镜消热差设计

根据坦克扫描光学系统的要求,设计了一种工作于8～12μm波段,可识别2 000 m远坦克目标的折/反/衍射混合红外消热差光学系统。该系统采用新型的卡塞格林系统,其非球面主镜和次镜全部取代为球面,解决了卡塞格林系统大口径非球面主镜、次镜的高加工精度和装调难的问题;通过应用衍射元件独特的温度特性实现红外光学系统的无热化设计,设计的系统结构简单紧凑,口径大、焦距长、分辨率高,并且在-40～60℃的温度范围内成像质量接近衍射极限,满足坦克扫描系统的总体要求和像质要求。     

The working mechanism of organic photovoltaic cell by using copper phthalocyanine as exciton blocking layer

We demonstrate the working mechanism of organic photovoltaic (OPV) cell with copper phthalocyanine (CuPc) as exciton blocking layer (EBL). The new EBL material CuPc, commonly has been used as electron donor in the organic solar cells due to its electron-donating and hole-transporting properties. But here we proves that the α-polymorph CuPc layer can transfer electrons to Al cathode through the half-filled b_1g level, this mechanism is different from that of general EBL material with larger band gap and electron-transporting property, which is based on damage states induced by the heat of evaporating Al.     

新型Sb基二类超晶格红外探测器

InAs/Ga(In)SbⅡ类超晶格材料由于特殊的二型能带结构,可以通过人造低维结构获得类似于体材料的带间吸收,从而获得较高的量子效率;另外,通过调节材料参数调节能带结构,器件响应波段可调;通过能带结构设计抑制俄歇复合,获得较小的暗电流和较高的器件性能。因为以上特有的材料性能和器件特性,Sb基二类超晶格在国际上被认为是第三代红外焦平面探测器的优选材料。对二类超晶格材料的设计和器件特性进行了研究,设计了峰值波长4μm的nBn结构的中波红外探测器,在没有蒸镀抗反膜的条件下,77 K温度下测试得到的峰值探测率为2.4×1011cm Hz1/2W-1,计算得到的量子效率为47.8%,峰值探测率已经接近目前的碲镉汞中波红外探测器器件性能。研究结果充分显示了二类超晶格优越的材料和器件性能。