Entanglement can Increase Asymptotic Rates of Zero-Error Classical Communication over Classical Channels

It is known that the number of different classical messages which can be communicated with a single use of a classical channel with zero probability of decoding error can sometimes be increased by using entanglement shared between sender and receiver. It has been an open question to determine whether entanglement can ever increase the zero-error communication rates achievable in the limit of many channel uses. In this paper we show, by explicit examples, that entanglement can indeed increase asymptotic zero-error capacity, even to the extent that it is equal to the normal capacity of the channel.     

运算放大器的进展

如何为不同应用选择最好的运算放大器。运算放大器自1963年问世以来,走过了很长的发展道路,并成为所有线性系统中事实上的标准部件。几乎每个大型半导体制造商的产品线中都有运算放大器这个产品。而且应用场合的不同也促使放大器的封装从TO-8的金属罐状封装发展至2mm×2mm的芯片式封装,如图1所示。目前放大器的性能水平已达到了如下指标,这在20世纪60年代是闻所未闻的。●带宽超过1GHz;●转换速率超过5000V/μs;●工作电流低于10μA;●工作电压低至0.9V;●输入失调电压低于20μV。C M O S与双极性工艺制造工艺和前沿设计技术的进步使得…     

Ethyl 6‐amino‐2‐methoxypyridine‐3‐carboxyl­ate,interplay of molecular and supramolecular structure

The title compound, C₉H₁₂N₂O₃, crystallizes with two mol­ecules in the asymmetric unit. There is extensive hydrogen bonding which results in the formation of a two‐dimensional corrugated sheet. This supramolecular structure is determined by the formation of hydrogen‐bonded chains resulting from the presence of a 6‐amino group and an ethoxy­carbonyl group as substituents on a pyridine ring in relative para positions which constitute a π‐electron `push–pull' system.     

Tuning Electrical and Thermal Transport in AlGaN/GaN Heterostructures via Buffer Layer Engineering

Progress in wide bandgap, III–V material systems based on gallium nitride (GaN) has enabled the realization of high‐power and high‐frequency electronics. Since the highly conductive, 2D electron gas (2DEG) at the aluminum gallium nitride (AlGaN)/GaN interface is based on built‐in polarization fields and is confined to nanoscale thicknesses, its charge carriers exhibit much higher mobilities compared to their doped counterparts. This study shows that such 2DEGs also offer the unique ability to manipulate electrical transport separately from thermal transport, through the examination of fully suspended AlGaN/GaN diaphragms of varied GaN buffer layer thickness. Notably, ≈100 nm thin GaN layers can considerably impede heat flow without electrical transport degradation. These achieve 4× improvement in the thermoelectric figure of merit (zT) over externally doped GaN, with state‐of‐the‐art power factors of 4–7 mW m^‐1 K^‐2. The remarkable tuning behavior and thermoelectric enhancement, elucidated here for the first time in a polarization‐based heterostructure, are achieved because electrons are at the heterostructured interface, while phonons are within the material system. These results highlight the potential for using 2DEGs in III–V materials for on‐chip thermal sensing and energy harvesting.     

Four- and Five-Coordinate Oxovanadium(V) Alkoxides: Do Steric Effects or Electronic Properties Dictate the Geometry?

Sterically hindered ligands generally form metal complexes with lower coordination numbers than less hindered ligands. In contrast to dogma, the solid state vanadium(V) complexes with ethylene glycol and pinacol contain four- and five-coordinate vanadium atoms, respectively. Ab initio and electrostatic potential distribution calculations were conducted on both experimental and optimized geometries of the four- and five-coordinate oxovanadium chloroalkoxides. Ab initio energy calculations favor the five-coordinate species for all ligands at all levels of theory examined. No significant differences in the electrostatic properties of the vanadium atoms in the two types of molecules were observed by using electrostatic potential distribution analysis. Methyl group substitutions on the ligand did not change the electronics of the vanadium atoms sufficiently to be a factor. Thus, we conclude that neither electronics nor sterics at the metal center explains the experimental geometries. In the absence of a significant observable electronic effect at the vanadium, we note that the experimental observations can be attributed to ligand geometric effects such as the Thorpe-Ingold and/or gem-dialkyl effects.     

Effect of ring strain on the thiolate-disulfide exchange. A computational study

B3LYP/aug-cc-pVDZ and MP2/6-31+G calculations of the reactions of HS(-) with small cyclic disulfides (dithiirane, 1,2-dithietane, 1,2-dithiolane, and 1,2-dithiane) were performed to determine the reaction mechanism. For the five- and six-membered rings, the reaction proceeds via the addition-elimination pathway, consistent with acyclic analogues. The smaller, more strained three- and four-membered rings react by the S(N)2 mechanism. Addition of the nucleophile cannot be accommodated by the small rings without concomitant ring cleavage.     

Solid state structure and solution conformation of a macrobicyclic cyclophane

X-ray crystallographic structure determination of the macrobicyclic cyclophane L¹ reveals a compact structure involving close edge-to-face approach of aromatic rings; ¹H nmr shows that this is also the solution conformation.     

Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cells

The maintenance of whole-body glucose homeostasis is critical for survival, and is controlled by the coordination of multiple organs and endocrine systems. Pancreatic islet β cells secrete insulin in response to nutrient stimuli, and insulin then travels through the circulation promoting glucose uptake into insulin-responsive tissues such as liver, skeletal muscle and adipose. Many of the genes identified in human genome-wide association studies of diabetic individuals are directly associated with β cell survival and function, giving credence to the idea that β-cell dysfunction is central to the development of type 2 diabetes. As such, investigations into the mechanisms by which β cells sense glucose and secrete insulin in a regulated manner are a major focus of current diabetes research. In particular, recent discoveries of the detailed role and requirements for reorganization/remodeling of filamentous actin (F-actin) in the regulation of insulin release from the β cell have appeared at the forefront of islet function research, having lapsed in prior years due to technical limitations. Recent advances in live-cell imaging and specialized reagents have revealed localized F-actin remodeling to be a requisite for the normal biphasic pattern of nutrient-stimulated insulin secretion. This review will provide an historical look at the emergent focus on the role of the actin cytoskeleton and its regulation of insulin secretion, leading up to the cutting-edge research in progress in the field today.     

How environment affects drug activity: Localization,compartmentalization and reactions of a vanadium insulin-enhancing compound,dipicolinatooxovanadium(V)

The chemical and biological properties of a simple and traditional V(5+) coordination complex, dipicolinatooxovanadium(V) (abbreviated [VO₂dipic]^?), are described in order to present a hypothesis for a novel mode of action wherein a hydrophobic membrane environment plays a key role. Specifically, we propose that the compartmentalization and both chemical and biological transformations of vanadium-complexes direct whether beneficial or toxic effects will be observed with this class of compounds. This concept is based on the formation of high levels of uncontrollable reactive oxygen species (ROS) from one-electron reactions or alternative events possibly initiated by a two-electron reaction which may be directly or indirectly beneficial by reducing the high levels of ROS. The properties of dipicolinatooxovanadium(V) compounds in aqueous solution (D.C. Crans, et al., Inorg. Chem. 39 (2000) 4409–4416) are very different from those in organic solvents (S.K. Hanson, et al., J. Am. Chem. Soc. 131 (2009) 428–429) and these differences may be key for their mode of action. Since other vanadium complexes are known to hydrolyze upon administration, the low stability of the aqueous complex requires entrapment in hydrophobic environments for such a complex to exist sufficiently long to have an effect. The suggestion that the environment changes the reactivity of the compounds is consistent with the very different modes of action by which one complex act. In short, a novel hypothesis is presented for a mode of action of vanadium compounds based on differences in properties resulting from environmental conditions. These considerations are supported by recent evidence supporting a role for membranes and signal transduction events (D.A. Roess, et al. Chem. Biodivers. 5 (2008) 1558–1570) of the insulin-enhancing properties of these compounds.