Hitherto-Unexplored Photodynamic Therapy of Ag2S and Enhanced Regulation Based on Polydopamine In Vitro and Vivo

Given their superior penetration depths, photosensitizers with longer absorption wavelengths present broader application prospects in photodynamic therapy (PDT). Herein, Ag₂S quantum dots were discovered, for the first time, to be capable of killing tumor cells through the photodynamic route by near-infrared light irradiation, which means relatively less excitation of the probe compared with traditional photosensitizers absorbing short wavelengths. On modification with polydopamine (PDA), PDA-Ag₂S was obtained, which showed outstanding capacity for inducing reactive oxygen species (increased by 1.69 times). With the addition of PDA, Ag₂S had more opportunities to react with surrounding O₂, which was demonstrated by typical triplet electron spin resonance (ESR) analysis. Furthermore, the PDT effects of Ag₂S and PDA-Ag₂S achieved at longer wavelengths were almost identical to the effects produced at 660 nm, which was proved by studies in vitro. PDA-Ag₂S showed distinctly better therapeutic effects than Ag₂S in experiments in vivo, which further validated the enhanced regulatory effect of PDA. Altogether, a new photosensitizer with longer absorption wavelength was developed by using the hitherto-unexplored photodynamic function of Ag₂S quantum dots, which extended and enhanced the regulatory effect originating from PDA.     

Characteristics of black carbon aerosol in Jiaxing,China during autumn 2013

We conducted measurements of black carbon（BC） aerosol in Jiaxing,China during autumn from September 26 to November 30,2013.We investigated temporal and diurnal variations of BC,and its correlations with meteorological parameters and other major pollutants.Results showed that hourly mass concentrations of BC ranged from 0.2 to 22.0 μg/m³,with an average of 5.1 μg/m³.The diurnai variation of BC exhibited a bimodal distribution,with peaks at 07:00 and 18:00.The morning peak was larger than the evening peak.The mass percentages of BC in PM_2.5 and PM₁₀ were 7.1%and 4.8%,respectively.The absorption coefficient of BC was calculated to be 44.4 Mm^-1,which accounted for 11.1%of the total aerosol extinction.BC was mainly emitted from local sources in southwestern Jiaxing where BC concentrations were generally greater than 11 μg/m³ during the measurement period.Correlation analysis indicated that the main sources of BC were motor vehicle exhaust,and domestic and industrial combustion.     

Synthesis and Self-Assembly of Mixed-Graft Block Copolymers

Mixed-graft block copolymers (mGBCPs) consist of two or more types of polymeric side chains grafted on a linear backbone in a random, alternating, or pseudo-alternating sequence. They can phase-separate with the backbone serving as the interface of the blocks, and the side chains dominate their self-assembly behavior. mGBCPs are an accessible polymer architecture for exploring the idea of encoding polymer properties through the macromolecular architecture, as there are two distinct structural components that can be tuned: the backbone and the side chains. In this Concept article, the current literature on the synthesis of mGBCPs is reviewed, and the advantages and disadvantages of each synthetic method are noted. The self-assembly of mGBCPs is also discussed where possible. Finally, directions for future research on mGBCP synthesis and self-assembly are suggested.     

推进农村通信和信息化发展的若干建议

农村地区的通信和互联网建设,是全面建设小康社会的重要基础设施之一,是一项艰巨、繁重的任务.信息产业部制定的不同时期的电信发展目标规划,具有求实性、可操作性.思前想后,各级政府的政策支持和电信运营企业尽责参与,仍是推进农村通信和农村信息化快速发展之路.然而,在电信普遍服务基金渠道、农村通信设备选用、农村信息化模式、地域目标规划等方面尚需论证落实,这是稳步实现电信小康目标的保障.     

Asymptotics of the necessary sample size under small error probabilities

The asymptotics of the necessary sample size is considered in testing close hypotheses when the error probabilities vanish. Proceedings of the XVII Seminar on Stability Problems for Stochastic Models, Kazan, Russia, 1995, Part III.     

光纤白光干涉仪等臂长技术研究

介绍了几种光纤干涉仪等臂长技术,比较了各自的优缺点和适用范围,对光纤干涉仪的平衡有较大的参考价值。     

Analysis of queueing policies in QoS switches

It is widely accepted that next-generation networks will provide guaranteed services, in contrast to the “best effort” approach today. We study and analyze queueing policies for network switches that support the QoS (Quality of Service) feature. One realization of the QoS feature is that packets are not necessarily all equal, with some having higher priorities than the others. We model this situation by assigning an intrinsic value to each packet. In this paper we are concerned with three different queueing policies: the nonpreemptive model, the FIFO preemptive model, and the bounded delay model. We concentrate on the situation where the incoming traffic overloads the queue, resulting in packet loss. The objective is to maximize the total value of packets transmitted by the queueing policy. The difficulty lies in the unpredictable nature of the future packet arrivals. We analyze the performance of the online queueing policies via competitive analysis, providing upper and lower bounds for the competitive ratios. We develop practical yet sophisticated online algorithms (queueing policies) for the three queueing models. The algorithms in many cases have provably optimal worst-case bounds. For the nonpreemptive model, we devise an optimal online algorithm for the common 2-value model. We provide a tight logarithmic bound for the general nonpreemptive model. For the FIFO preemptive model, we improve the general lower bound to 1.414, while showing a tight bound of 1.434 for the special case of queue size 2. We prove that the bounded delay model with uniform delay 2 is equivalent to a modified FIFO preemptive model with queue size 2. We then give improved upper and lower bounds on the 2-uniform bounded delay model. We also show an improved lower bound of 1.618 for the 2-variable bounded delay model, matching the previously known upper bound.     

基于μCLinux的NAT设备的设计与开发

NAT(网络地址翻译)技术有效地解决了IP地址紧缺的问题,为实现IPv4到IPv6的平滑过渡发挥了巨大的作用.在一个体积小、重量轻、价格低廉的嵌入式平台上实现NAT设备具有很好的实际意义.文中介绍了NAT技术的原理和实现过程,在自行设计的ARM7嵌入式硬件平台上基于μCLinux操作系统实现了NAT的功能,并通过实现其他相关功能,构建了完整的NAT设备,完成了小型网络接入Internet的方案.     

内网安全新时空--宝信网络巡警eCop典型案例分析

内网安全的重要性网络的发展给工作带来巨大便利的同时也带来了众多安全隐患,有关网络信息安全的问题日益突出。目前绝大多数的企业、学校、政府机构把安全重点放在防范来自外部的攻击,依赖于防火墙、防病毒、入侵检测等软件。尽管在所有介绍系统安全的文献中都会提及来自于内部的安全威胁,却鲜有针对内部安全隐患的防范工具与手段。2003年美国CSI/FBI提供的《计算机犯罪与安全调查报告》显示,80%以上的信息安全事件为内部人员和内外勾结所为。尤其近几年来,随着个人技术水平的提高,IP地址非法占用和盗用、非法外联现象、计算机基本信息…