Dark Energy Models and Cosmic Acceleration with Anisotropic Universe in f（T） Gravity

This paper is devoted to studing the accelerated expansion of the universe in context of f（T） theory of gravity. For this purpose, we construct different f（T） models and investigate their cosmological behavior through equation of state parameter by using holographic, new agegraphic and their power-law entropy corrected dark energy models. We discuss the graphical behavior of this parameter versus redshif~ for particular values of constant parameters in Bianchi type I universe model. It is shown that the universe lies in different forms of dark energy, namely quintessence, phantom, and quintom corresponding to the chosen scale factors, which depend upon the constant parameters of the models.     

Aurones and Analogues: Promising Heterocyclic Scaffolds for Development of Antioxidant and Antimicrobial Agents

Russian Journal of General Chemistry - Synthesis of some new multi-functional analogues of 2′-hydroxy chalcone containing isoxazole and pyrazole functions were synthesized, and their...     

Exact solutions of perturbed nonlinear Schrödinger’s equation with Kerr law nonlinearity by improved $${\textbf{tan}} \left( {\frac{{\boldsymbol{\phi}} \left( {\boldsymbol{\xi}} \right)}{{\textbf{2}}}} \right)$$-expansion method

This paper carries out exact solutions of the perturbed nonlinear Schödinger’s equation withy Kerr law nonlinearity by using the improved tan\(\left( {\frac{\phi \left( \xi \right)}{2}} \right)\)-expansion method. The exact solutions contain four types: hyperbolic function solution, trigonometric function solution, exponential solution, and rational solution. The method appears to be easier and faster by means of symbolic computational system and can be applied to the other nonlinear evolution equations in mathematical physics.     

Phytochemical Characterizations of Maranthes polyandra (Benth.) Prance

Two new ursane-type triterpenoids, named Polyanside A (1) and B (2), along with eleven known compounds (3–13), were isolated and elucidated from Maranthes polyandra (Benth.) Prance. The structures of these compounds were elucidated based on chemical evidence and multiple spectroscopic data. Isolated compounds were evaluated for anti-cancer, anti-inflammatory activities, and cytotoxicity on a normal human cell line (BJ). None of them showed activity and cytotoxicity. The hexane fraction was analyzed by GC-MS, resulting in the identification of forty-one compounds. This is the first comprehensive study on the phytochemistry of M. polyandra.     

Polyphenolic Composition,Antioxidant, Antiproliferative and Antidiabetic Activities of Coronopus didymus Leaf Extracts

Coronopus didymus (Brassicaceae) commonly known as lesser swine cress has been reported to be used for its pharmacological activities. This study aimed to evaluate the medicinal potential of C. didymus extracts against cancer, diabetes, infectious bacteria and oxidative stress and the identification of bioactive compounds present in these extracts. The effects of using different solvents for the extraction of C. didymus on the contents of major polyphenols and biological activities were investigated. Plant sample was shade dried, ground to a fine powder, and then soaked in pure acetone, ethanol and methanol. The highest contents of major polyphenols were found in methanol-based extract, i.e., chlorogenic acid, HB acid, kaempferol, ferulic acid, quercetin and benzoic acid with 305.02, 12.42, 11.5, 23.33, 975.7 and 428 mg/g of dry weight, respectively, followed by ethanol- and acetone-based extracts. The methanol-based extract also resulted in the highest antioxidant activities (56.76%), whereas the highest antiproliferative (76.36) and alpha glucosidase inhabitation (96.65) were demonstrated in ethanol-based extracts. No antibacterial property of C. didymus was observed against all the tested strains of bacteria. Further studies should be focused on the identification of specific bioactive compounds responsible for pharmacological activities.     

Synthesis of cellulose–metal nanoparticle composites: development and comparison of different protocols

Deposition of nanoparticles on the surface of a variety of materials is a subject of great interest due to their potential applications in electronic devices, sensing, catalysis and bio-medical sciences. In this context, we have explored and compared various methodologies to generate gold and silver nanoparticles on the surface of cellulose fibers. It was found that boiling of the cellulose fibers in alkaline solution of gold and silver salts led to the formation and immobilization of gold and silver nanoparticles. However, in case of lecithin treated and thiol-modified cellulose fibers, high temperature was not essentially required for the formation and deposition of nanoparticles on cellulose substrate. In both these cases, fairly uniform metal nanoparticles were obtained in good yields (~43 wt% gold loading in case of thiol modified cellulose fibers) at room temperature. Borohydride-reduction method resulted in relatively lower loading (~22 wt%) with a wide size distribution of gold and silver nanoparticles on cellulose fibers. All these nanoparticle–cellulose composites were thoroughly characterized using scanning electron microscopy, energy dispersive X-ray, Fourier transform infrared spectroscopy, UV–visible spectroscopy, and elemental analyzer. Thiol modified cellulose–gold nanoparticle composites served as active catalysts in the reduction of 4-nitrophenol into 4-aminophenol.     

Fixed-Dose Combination Antibiotics Interacting with a Quaternary Ammonium Disinfectant: Insights from Spectral and Chromatographic Measurements

Core–shell architecture of surfactant micelles can act to shield active drug molecules from the adverse environmental conditions and enhance their bioavailability. In the present study the molecular interactions of a fixed dose combination (FDC) containing ofloxacin (OFX) and ornidazole (ORN), with cetyltrimethylammonium bromide (CTAB, a quaternary ammonium surfactant) were investigated under normal physiological pH (pH 7.4?±?0.1). The impact of the cationic micelle on the spectral and physiochemical properties of the FDC components OFX and ORN was systematically examined by electronic spectroscopy. Micellar liquid chromatography and differential spectral methods were used to optimize analysis of the magnitude of binding constants and related Gibbs energies. The results suggest the potential solubilization of drugs in the external part of the micelles, which may prove to be more helpful for their controlled release. These outcomes have been verified by the binding capacities of drug–CTAB combinational system that may be helpful to customize the uptake of drug molecules in cells.     

A secure and efficient remote patient‐monitoring authentication protocol for cloud‐IoT

The ongoing Cloud‐IoT (Internet of Things)–based technological advancements have revolutionized the ways in which remote patients could be monitored and provided with health care facilities. The real‐time monitoring of patient's health leads to dispensing the right medical treatment at the right time. The health professionals need to access patients' sensitive data for such monitoring, and if treated with negligence, it could also be used for malevolent objectives by the adversary. Hence, the Cloud‐IoT–based technology gains could only be conferred to the patients and health professionals, if the latter authenticate one another properly. Many authentication protocols are proposed for remote patient health care monitoring, but with limitations. Lately, Sharma and Kalra (DOI: 10.1007/s40998‐018‐0146‐5) present a remote patient‐monitoring authentication scheme based on body sensors. However, we discover that the scheme still bears many drawbacks including stolen smart card attack, session key compromise, and user impersonation attacks. In view of those limitations, we have designed an efficient authentication protocol for remote patient health monitoring that counters all the above‐mentioned drawbacks. Moreover, we prove the security features of our protocol using BAN logic‐based formal security analysis and validate the results in ProVerif automated security tool.     

Phytochemical screening and chemical variability in volatile oils of aerial parts of Morinda morindoides

Morinda morindoides is an important Liberian traditional medicine for the treatment of malaria, fever, worms etc. The plant was subjected to integrated approaches including phytochemical screening and gas chromatography mass spectrometry (GC–MS) analyses. Phytochemical investigation of the powdered plant revealed the presence of phenolics, tannins, flavonoids, saponins, terpenes, steroidal compounds and volatile oil. Steam distillation followed by GC–MS resulted in the identification of 47 volatiles in its aerial parts: 28 were in common including various bioactive volatiles. Major constituents of leaves were phytol (43.63%), palmitic acid (8.55%) and geranyl linalool (6.95%) and stem were palmitic acid (14.95%), eicosane (9.67%) and phytol (9.31%), and hence, a significant difference in the percentage composition of aerial parts was observed. To study seasonal changes, similarity analysis was carried out by calculating correlation coefficient (r) and vector angle cosine (z) that were more than 0.91 for stem-to-stem and leaf-to-leaf batches indicating considerable consistency.     

Size-controlled synthesis of near-monodisperse gold nanoparticles in the 1-4 nm range using polymeric stabilizers

We report here a simple one-step protocol for the preparation of near-monodisperse gold hydrosols in the small size regime (<5 nm). The particle size can be controlled by varying the concentration of the stabilizing polymer, which can be readily displaced by thiol ligands to yield monolayer protected clusters of the usual type.