基于FPGA的多通道模拟信号源设计

针对航天测试领域对模拟信号源的设计要求,提出一种新的信号源实现方法。该方法借助计算机软件能实时编程生成波形数据,通过对波形重构电路,调理电路和多通道电路的合理设计,由FPGA控制逻辑实现波形重构和多通道输出。由于方波信号沿变时具有的特殊性,设计专门的方波产生电路,通过实验验证,对原先设计电路的阻尼特性加以改进,实现了方波信号高精度的可靠输出,满足技术指标要求。目前,该信号源已广泛应用于多项航天测试项目。     

基于DDR2 SDRAM乒乓双缓冲的高速数据收发系统设计

在高速数据收发系统设计中,首先需要解决的问题是实时数据的高速缓存,然而FPGA内部有限的存储资源无法满足海量数据缓存的要求。为了解决系统中海量数据的缓存问题,系统创新提出了一种基于DDR2 SDRAM的乒乓双缓冲设计方案。方案设计了两路基于DDR2 SDRAM的大容量异步FIFO,通过FPGA内部选择逻辑实现两条通路间的乒乓操作,从而实现数据的高速缓存。实验结果表明,基于DDR2 SDRAM的数据收发系统实现了每路512 Mbit的缓存空间和200 MHz的总线速率,解决了海量数据的高速缓存问题。     

Sub-1 V band-gap based and MOS threshold-voltage based voltage references in 0.13 µm CMOS

Portable and implantable device applications require low supply voltage reference circuits due to increasing trend for lower power requirements. Voltage references have been proposed for operation below 1 V for CMOS and a comprehensive analysis of the behavior of the different topologies is needed for ultra-low power designs, in order to select the right circuit topology for a given requirement. This work compares two major classes of voltage reference topologies: threshold voltage (V_T0)-based and (V_G0) bandgap voltage-based reference circuits. Four different topologies of voltage-reference designs with 1-V supply were designed and fabricated in 130 nm CMOS process. Monte Carlo analysis shows the variability of the references and of their temperature coefficients (TC), and the results are compared to measured samples. Simulations and measurements show that the threshold voltage-based references are more susceptible to the variations in the CMOS fabrication process.     

基于STM8S的室内甲醛检测系统设计

针对目前越来越严重的室内甲醛污染问题,设计了以STM8S为控制核心的便携式室内甲醛检测系统。该系统创造性地设计了一种基于减法器的硬件抗干扰电路,克服了以往甲醛电化学传感器检测设计电路中,采用温、湿敏电阻对传感器温、湿度系数进行补偿所造成的测量精度不足问题,并结合采样滤波算法和拉格朗日插值算法对采集的数据进行软优化。系统具有甲醛浓度阈值设定与超限报警功能,温度、湿度、万年历显示等辅助功能,真正实现了便携式与智能化的结合。实验结果证明,该系统在实际应用中具有较高的灵敏度、准确度、操作简单、性价比高等特色,还可推广应用于其他需要对甲醛浓度进行检测的场合。     

用于速调管的一维光子晶体圆柱腔分析

运用ISFEL3D软件对一维光子晶体圆柱腔和金属圆柱腔进行仿真和分析。研究结果表明,一维光子晶体圆柱腔中与TM010模相邻的TM910模只存在于最外层介质中,频率间隔为213 MHz,不会影响TM010模;一维光子晶体圆柱腔的特性阻抗(94.9Ω)比金属圆柱腔(129Ω)要小,但均匀性要好;在一维光子晶体圆柱腔两端连接漂移管后,TM010模所受影响很小,说明一维光子晶体圆柱腔具有较强的抗干扰能力,这是将一维光子晶体圆柱腔应用在高射频段速调管方面的前提条件。     

提升LED驱动芯片视觉刷新率的逻辑电路设计

为了提升LED显示屏的画面质量,设计了能提高LED显示屏视觉刷新率的逻辑电路。该电路将一个显示周期分为32段,每一段包含有128个灰度时钟周期,占空比由12位灰度数据控制。逻辑电路产生的PWM和传统的PWM相比能提高视觉刷新率,最高能将视觉刷新率提高至32倍;能弥补S-PWM( Scrambled-PWM)在灰度数据低时视觉刷新率低的不足。在Cadence软件下进行设计仿真,并在开发板上进行了验证设计的可行性。     

磁控溅射LaB6薄膜光学性能研究

采用磁控溅射法在玻璃基片上沉积LaB6薄膜。通过改变溅射功率参数,获得最佳制备工艺条件。采用XPS、X射线衍射仪和分光光度计研究薄膜的成分、结构、晶向以及透过率。当溅射功率为44 W,氩气气压为1.5 Pa,氩气流量为27 sccm时制备的LaB6薄膜表面相对平整,结构致密。 XRD数据也表明,此时LaB6薄膜结晶度最高且(110)晶面发生明显的择优生长。同时分光光度计结果显示：薄膜的透过率随溅射时间的增加而降低,并且最高透过率对应的波长没有发生变化。     

Random Copolymers of 1,5-Dioxepan-2-one

ABSTRACT

Copolymers of 1,5-dioxepan-2-one (DXO) and e-caprolactone (?-CL), δ-valerolactone (δ-VL) or L-lactide (LLA) have been synthesized and characterized. High molecular weight copolymers were obtained using stannous-2-ethyl hexanoate as catalyst in bulk. Reactivity ratios for the copolymerization of DXO and δ-VL were determined at 110°C as r_VL=0.5 and r_DXO=2.3. At high conversion, depolymerization of δ-VL occurred, resulting in lower molecular weight and variations in the copolymer composition.

Physical properties, such as crystallinity and melting temperature of the DXO-copolymers proved to be strongly dependent on the choice of comonomer and on the molar composition of the copolymers. DXO appears to be incorporated into the poly-?-caprolactone (PCL) crystals and to some extent into the poly-δ-valerolactone (PVL) crystals, resulting in a more gradual decrease in crystallinity with increasing amount of DXO.     

U6 is unsuitable for normalization of serum miRNA levels in patients with sepsis or liver fibrosis

MicroRNA (miRNA) levels in serum have recently emerged as potential novel biomarkers for various diseases. miRNAs are routinely measured by standard quantitative real-time PCR (qPCR); however, the high sensitivity of qPCR demands appropriate normalization to correct for nonbiological variation. Presently, RNU6B (U6) is used for data normalization of circulating miRNAs in many studies. However, it was suggested that serum levels of U6 themselves might differ between individuals. Therefore, no consensus has been reached on the best normalization strategy in ‘circulating miRNA''. We analyzed U6 levels as well as levels of spiked-in SV40-RNA in sera of 44 healthy volunteers, 203 intensive care unit patients and 64 patients with liver fibrosis. Levels of U6 demonstrated a high variability in sera of healthy donors, patients with critical illness and liver fibrosis. This high variability could also be confirmed in sera of mice after the cecal ligation and puncture procedure. Most importantly, levels of circulating U6 were significantly upregulated in sera of patients with critical illness and sepsis compared with controls and correlated with established markers of inflammation. In patients with liver fibrosis, U6 levels were significantly downregulated. In contrast, levels of spiked-in SV40 displayed a significantly higher stability both in human cohorts (healthy, critical illness, liver fibrosis) and in mice. Thus, we conclude that U6 levels in the serum are dysregulated in a disease-specific manner. Therefore, U6 should not be used for data normalization of circulating miRNAs in inflammatory diseases and previous studies using this approach should be interpreted with caution. Further studies are warranted to identify specific regulatory processes of U6 levels in sepsis and liver fibrosis.     

Application of thermovision for estimation of the optimal and safe parameters of the whole body cryotherapy

Exposure to the extreme low temperatures, ranging between ?60 and ?140 °C, has many beneficial effects on the human body what is exploited for example in sport medicine, for treatment of locomotory system diseases or even some psychiatric disorders. To insure the safe treatment in a cryochamber, careful planning of the procedure and proper qualification of patients, is required. Cardiovascular system, especially skin vasculature plays the major role of the body response to the extreme cold. The changes in skin blood flow are reflected in changes of the temperature distribution. Therefore, the thermal imaging, which allows to analyze the temperature distribution on the human body, may be successfully exploited to examine the influence of extremely low temperatures on the skin vascular system. The aim of this work was to examine the temperature, blood pressure, and heart rate changes after the whole body cryotherapy in healthy subjects to determine the safety conditions of the treatment. 480 healthy students of the Wroc?aw University School of Physical Education were divided into two groups (each 240 persons). All subjects were exposed for 1–3 min to the extremely low temperatures: ?60, ?100, ?120, and ?140 °C. In one group, the thermograms were recorded before and 5 and 30 min after the cryotherapy by means of ThermoVision A20 M thermal camera. In the other one, heart rate and blood pressure were measured before and 5 min after the cryotherapy. It was demonstrated that 3-min exposure in the cryochamber and the temperature ?120 °C are the optimal and safe cryotherapy parameters.