Multiresidue analysis of pesticides with hydrolyzable functionality in cooked vegetables by liquid chromatography tandem mass spectrometry

It would be preferable for pesticide residues substituted by hydrolyzable functionality to be analyzed after cooking because their structures are apt to degrade during boiling and/or heating. A liquid chromatography–tandem mass spectrometry (LC‐MS/MS) method for the quantitative determination of 44 pesticide residues with hydrolyzable functional group in five typical vegetable widely consumed in Republic of Korea is described. The sample clean‐up was carried out according to the method of Food Code No. 83 established by the Korea Food and Drug Administration (KFDA). Zorbox XDB‐C₁₈ column was selected for the analysis because of the best peak separation. The LC mobile phase consisted of water and 5 mm methanolic ammonium formate, which resulted in a peak shape with good symmetry at each run. Tandem mass spectroscopic (MS/MS) experiments were performed in ESI positive mode and the multiple reaction monitoring modes. A conventional matrix effect was modified to more comprehensive form 100γ_ij (%). A high matrix effect (相似文献   

Studies on Fused Azoles: Synthesis of Several Polyfunctionally Substituted Fused Azoles

The synthesis of several new polyfunctionally substituted fused pyrazoles via reaction of 5‐amino‐3‐methylthio‐1H‐pyrazole‐4‐carboxylate ( 2 ) with different reagents is described.     

Treatment of the emission and absorption spectra for a Λ-type three-level atom driven by a single-mode field with nonlinearities

The treatment of a Λ-type three-level atom interacting with a single mode field in a cavity, explicitly taking the existence of forms of nonlinearities of both the field and the intensity-dependent atom-field coupling into account. Analytical expressions of the emission and absorption spectra are presented using the dressed states of the system. The characteristics of the emission and absorption spectra for binomial state and squeezedcoherent state inputs are exhibited. The effects of the mean number of photons, the detuning, and the nonlinearities on the spectra are investigated. It is shown that the features of the fluorescence and absorption spectra are influenced significantly by the kinds of nonlinearities.     

Ethanol oxidation at metal–zeolite-modified electrodes in alkaline medium. Part 2: palladium–zeolite-modified graphite electrode

Impregnated Pd–zeolite graphite (PdZG) electrodes have been tested for ethanol oxidation in 0.5 M NaOH. The results obtained have been compared with that of Pd electrode. Cyclic voltammetric and chronoamperometric measurements indicated the activity of PdZG electrode toward ethanol oxidation and poisoning tolerance. The influence of zeolite loading as well as impregnation time in Pd²⁺ solution has been examined. Scan rate effect and ethanol concentration dependency indicated that ethanol oxidation at PdZG electrode was governed by diffusion control.     

Development and Characterization of Novel Biopolymer Derived from Abelmoschus esculentus L. Extract and Its Antidiabetic Potential

Abelmoschus esculentus (Okra) is an important vegetable crop, widely cultivated around the world due to its high nutritional significance along with several health benefits. Different parts of okra including its mucilage have been currently studied for its role in various therapeutic applications. Therefore, we aimed to develop and characterize the okra mucilage biopolymer (OMB) for its physicochemical properties as well as to evaluate its in vitro antidiabetic activity. The characterization of OMB using Fourier-transform infrared spectroscopy (FT-IR) revealed that okra mucilage containing polysaccharides lies in the bandwidth of 3279 and 1030 cm⁻¹, which constitutes the fingerprint region of the spectrum. In addition, physicochemical parameters such as percentage yield, percentage solubility, and swelling index were found to be 2.66%, 96.9%, and 5, respectively. A mineral analysis of newly developed biopolymers showed a substantial amount of calcium (412 mg/100 g), potassium (418 mg/100 g), phosphorus (60 mg/100 g), iron (47 mg/100 g), zinc (16 mg/100 g), and sodium (9 mg/100 g). The significant antidiabetic potential of OMB was demonstrated using α-amylase and α-glucosidase enzyme inhibitory assay. Further investigations are required to explore the newly developed biopolymer for its toxicity, efficacy, and its possible utilization in food, nutraceutical, as well as pharmaceutical industries.     

Mesoionic 1,2,4-triazolo[4,3-c]quinazolines

Because of the close structural similarity between triazoloquinazolines and certain 5-membered ring mesoionic heterocycles, all of which possess antiinflammatory activity, we prepared several examples of the novel mesoionic 1,2,4-triazolo[4,3-c]quinazoline ring system for their therapeutic potential. These compounds can be prepared by the cyclization of the appropriately substituted 4-hydrazinoquinazolines with phosgene. When the mesoionic product was unsubstituted at the 5-position (i.e., quinazoline 2-position), it could only be isolated as its hydrochloride salt and not as its unstable free base. None of the mesoionic products were sufficiently stable in solution to allow for evaluation of their antiinflammatory activity.     

A Cross Layer Scheduling Framework for Supporting Bursty Data Applications in WCDMA Networks

In future wireless networks multimedia applications are expected to finally dominate the overall traffic volume. Shared channels are more suitable for the transmission of this type of traffic, as they are able to periodically adjust their transmission rate. In this paper, we introduce a cross-layer framework for WCDMA based networks which aims to make the packet scheduling procedure more efficient. In addition to that, we further propose a traffic scheduling scheme which serves the connections not only according to their delay sensitivity, but also according to the predicted state of their wireless channel. The efficiency of the proposed scheme, in terms of average packet delay and channel utilization is verified via simulations.     

Characterizing multi‐hop localization for Internet of things

Deployments over large geographical areas in the Internet of Things (IoT) pose a major challenge for single‐hop localization techniques, giving rise to applications of multi‐hop localizations. And while many proposals have been made on implementations for multi‐hop localization, a close understanding of its characteristics is yet to be established. Such an understanding is necessary, and is inevitable in extending the reliability of location based services in IoT. In this paper, we study the characteristics of multi‐hop localization and propose a new solution to enhance the performance of multi‐hop localization techniques. We first examine popular assumptions made in simulating multi‐hop localization techniques, and offer rectifications facilitating more realistic simulation models. We identify the introduced errors to follow the Gaussian distribution, and the estimated distance follows the Rayleigh distribution. We next use our simulation model to characterize the effect of the number of hops on localization in both dense and sparse deployments. We find that, contrary to common belief, it is better to use long hops in sparse deployments, while short hops are better in dense deployments – despite the traffic overhead. Finally, we propose a new solution that decreases and manages the overhead generated during the localization process. Copyright © 2016 John Wiley & Sons, Ltd.     

Novel mono- and dinucleating ligands-containing artificial di- and tetrahistidine and their zinc(II) complexes as a structural phosphotriesterase models for the hydrolysis of p-nitrophenyl diphenylphosphate (p-NPDPP)

Two new artificial peptides with histidine side chains, namely N-methyl N,N′-bis(Im-bzl-l-histidylmethylestermethyl)amine L1 and N,N′,N″,N?-tetrakis(Im-bzl-l-histidylmethyl-estermethyl)ethylene diamine L2 have been synthesized and were shown to form stable zinc complexes [L1Zn(H₂O)₂](ClO₄)₂ 1 and [L2Zn₂(H₂O)₃](ClO₄)₄ 2, respectively. Solution studies (pH–¹NMR titrations) of the ligand L2 in the presence of zinc ions were also reported. The catalytic activity of zinc complex species 1 and 2 as structural phosphotriestrase models were tested on the hydrolysis/detoxification of p-nitrohenl diphenylphosphate (p-NPDPP). From the correlation between the pH-rate profiles and the species distribution curves, the catalytically active species could be identified. On the basis of R-dependence as well as the rate acceleration of each complex, the possibility of cooperative action of zincs in dinuclear zinc complex is debated.