Improving Sensitivity of Enzyme to Organophosphorous Compounds by Combining Experiment and Theory Methods

In this paper, we compared the sensitivities of AFEST(a thermophilic esterase from the archaea Archaeoglobus fulgidus) and acetylcholinesterase(AChE) towards five organophosphorus compounds(OPs) by means of molecular docking, and found that only the docking energy between AFEST and dichlorvos is lower than that between AChE and dichlorvos. Via the docking model of AFEST and dichlorvos, Arg43 was found to play an important role in the interaction between AFEST and dichlorvos by means of stabilizing the complex. Then mutant R43S was constructed, the IC₅₀(the concentration required to reduce virus-induced cytopathicity by 50% is estimated as 50% inhibitory concentration) of which to dichlorvos was lower than that of the wild type AFEST by a factor of 1.56, indicating the enhanced sensitivity of mutant R43S to dichlorvos. Combining of theory with experiment, we have obtained important structure-function information of AFEST, which will be helpful to the further studies of esterase.     

海胆状Eu2O3/Ag3VO4复合材料的水热合成及其光致发光性能

以硝酸银和氧化铕为金属源,P123为结构导向剂,乙醇和水为溶剂.本文通过前驱体合成路线,采用水热法得到海胆状Eu2 O3/Ag3 VO4微球,并探讨其合成条件;采用SEM、XRD、XPS等方法对样品进行了表征,并探讨了Eu2 O3/Ag3 VO4海胆状微纳米结构的形成过程.测试结果表明:在反应温度为80℃,反应时间为10 h时,所合成的海胆状Eu2 O3/Ag3 VO4微球直径约为4~5μm.针对合成的样品,研究了海胆状Eu2 O3/Ag3 VO4微球的光致发光性能,并考察Eu3+掺杂量对光致发光性能的影响,当Eu3+掺杂量为4;时,样品具有最好的光致发光性能.     

5G过载零星传输系统中的多用户检测技术性能分析

目前,机器通信具有大规模连接及零星传输的特点,大规模连接导致系统必须使用非正交的接入方式,而零星传输的特性则使接入用户行为具有稀疏性。基于以上特性,相关文献提出了基于压缩感知的多用户检测技术。从用户行为及用户数据的检测性能方面对多用户检测技术进行分析研究,并通过仿真分析得出新的结论：尽管非正交扩频码的互相关性会影响接收端对用户行为及用户数据的检测性能,但CS-MUD 仍然可以有效地支持大规模连接用户下稀疏传输的场景。     

空间光通信终端精跟踪伺服系统研究

为了提高空间光通信中的精跟踪伺服系统的跟踪精度,采用神经网络比例-积分-微分算法,解决精跟踪伺服系统设计中光斑抖动时变不确定性和压电陶瓷驱动中存在的迟滞、蠕变和位移非线性等不足。通过3层结构反向传播神经网络自学习方法,在线调整比例-积分-微分控制器的系数,控制压电陶瓷驱动精瞄偏转镜偏转,最终达到精跟踪伺服系统优化控制。进行了理论分析和实验验证,取得了室内精跟踪数据。结果表明,神经网络比例-积分-微分控制算法增强了伺服系统鲁棒性,并提高了伺服系统实时性;采用400Hz的CCD,精跟踪伺服系统对40Hz以下的抖动能有效抑制,基本能满足在空间光通信中跟踪带宽需要。     

Quantum Anti-Zeno Effect in Artificial Quantum Systems

In this paper, we study a quantum anti-Zeno effect (QAZE) purely induced by repetitive measurements for an artificial atom interacting with a structured bath. This bath can be artificially realized with coupled resonators in one dimension and possesses photonic band structure like Bloch electron in a periodic potential. In the presence of repetitive measurements, the pure QAZE is discovered as the observable decay is not negligible even for theatomic energy level spacing outside of the energy band of the artificial bath. If there were no measurements, the decay would not happen outside of the band. In this sense, the enhanced decay is completely induced by measurements through the relaxation channels provided by the bath. Besides, we also discuss the controversial golden rule decay rates originated from the van Hove's singularities and the effects of the counter-rotating terms.     

Study on the Preparation of Mercaptoacetic Acid-modified Heterophylla Shell and Its Application in Separation and Enrichment of Pb2+ in Environmental Samples

To increase the adsorption capacity of the Corylus heterophylla Fisch(HS) for Pb²⁺, HS was chemically modified using NaOH aqueous solution and 95% ethanol and was labeled as SHS; then SHS was chemically modified using mercaptoacetic acid. The SHS modified with mercaptoacetic acid(MHS) was characterized using FTIR, SEM, and XPS. The results indicated that the -SH group was present on MHS, and after Pb²⁺ adsorption, the absorption value of the characteristic peak of the -SH group decreased. The adsorption and desorption properties of this functionalized material were investigated as well as the influences of parameters, such as pH value, type of desorption reagent, dosage, flow rate and maximum sample volume. The Pb²⁺ adsorption of MHS reached a maximum with pH>5. The experimental data of Pb²⁺ adsorption using MHS were fitted using the Langmuir isothermal adsorption model, and a maximum adsorption capacity of 61.54 mg/g was obtained. This was much higher than the adsorption capacity of SHS before modification with the thiol group. After adsorption, MHS was desorbed using a 0.2 mol/L HCl solution, and the percent of desorption was higher than 99%. MHS was used as a solid-phase extractant in the analysis and determination of Pb²⁺ content in food and water samples, and the enrichment times achieved 150-fold.     

儒家理想人格对当代法律人品格塑造的启示

儒家理想人格是以儒家思想为基础, 追求理想的人生境界和终极目标的一种理想人格, 其基本内涵包括仁、 义、礼、智、信。儒家代表人物孔子和孟子所提倡的“仁者爱人”、“义礼为先”、“智信合一”的思想, 不仅于当世有益, 也对当代法律人的品格塑造具有重要的启示。当代法律人的品格塑造既要继承历史, 又要 尊重现实。为此, 必须注意以下三点:其一, 当代法律人的品格塑造要与建设法治强国相统一;其二, 当代法 律人品格塑造是一项系统的工程;其三, 当代法律人品格塑造要在实践中完成。     

用于MEMS陀螺阵列信号处理的OBE平滑算法

为提高MEMS陀螺的精度,提出了一种基于最优定界椭球(OBE)的平滑算法,并将其用于陀螺阵列信号的处理.首先,利用多个相同型号的MEMS陀螺构成阵列,测量同一角速率信号,并建立数据融合模型.对于融合问题而言,噪声统计特性的不确定会导致传统融合方法精度下降.为解决该问题,引入仅要求噪声未知但有界的集员估计理论,结合RTS平滑思想,提出一种新的平滑算法作为融合方法,它由前向滤波和反向平滑两个过程构成:前者采用集员估计理论中的OBE滤波估计角速率,后者则逆序执行OBE算法进一步提高估计精度.实验表明:该方法能够将陀螺的静态漂移由0.5130(°)/s降低到0.1368(°)/s;动态条件下,在有效跟踪载体角度变化的同时,将漂移由0.5343(°)/s降低到0.1704(°)/s,显著提高了陀螺的使用精度.     

小波分析在悬臂梁裂纹识别中的应用

基于空间信号的小波分析理论,将含裂纹悬臂梁前四阶振型信息直接用于小波变换,小波系数在空间域上的突变反映了裂纹的存在并指出了裂纹的位置.本文分析了前四阶振型对小波识别结果的敏感性,利用小波系数模极大值在尺度上的表现与Lipschitz指数之闻的关系建立了集中因子和裂纹深度之间的关系,以此来估计裂纹深度.鉴于实测信号往往是含噪声信号,分析了噪声对识别结果的影响规律.数值算例表明利用sym4小波对含裂纹梁的四阶振型信息进行小波分析可以准确地识别出裂纹的位置和深度;高阶振型对结构损伤较为敏感,高阶振型更适合于微裂纹和含噪声信息的处理,但高阶振型的非线性也会给裂纹识别带来一定的困难.使用本文方法进行结构裂纹参数识别,噪声对裂纹位置的影响只是指示清晰度的影响,基本不会产生错误的识别,而对裂纹深度的影响远比对位置的影响复杂,由于小波系数混入了噪声成分,从而增加了集中因子的取值,致使识别结果总是比真实结果偏大.     

基于小波分析与LSSVM的陀螺仪随机漂移建模

为了提高陀螺仪的使用精度,以陀螺仪随机漂移时间序列为研究对象,建立了基于小波分析和最小二乘支持向量机（LSSVM）的陀螺仪随机漂移模型。陀螺仪作为高精度敏感器件,其随机漂移信号具有非线性、弱平稳性等特点,难以补偿。为了提高补偿精度,这里采用小波分析对陀螺仪随机漂移信号进行多尺度分解,利用最小二乘支持向量机方法对重构后的近似序列和细节序列建立非线性子模型,最后将各子模型输出融合作为组合模型输出。最后将该算法用于动调陀螺仪的随机漂移建模,实验结果表明基于该组合算法的非线性模型能够有效地反映陀螺仪的随机漂移特性,建模效果明显优于直接采用LSSVM和ANN建立的模型。