用拉曼光谱研究抗癌药物落羽松醇和它的类似体

用拉曼光谱研究抗癌药物落羽松醇和它的类似体郑思定，舒莲美，洪田博喜（复旦大学分析测试中心上海２００４３３）（日本岗山理科大学）ＲａｍａｎＳｐｅｃｔｒｏｓｃｏｐｉｃＩｎｖｅｓｔｉｇａｔｉｏｎｏｆｔａｘｏｌａｎｄＩｔｓＡｎａｌｏｇｕｅｓ￥ＺｈｅｎｇＳｉｄ...     

在黑龙江省珠算协会四届三次理事会议上的讲话

各位领导、各位理事、同志们: 今天,省珠协在这里召开四届三次理事会议,总结1995年工作.安排部署1996年工作,并且表彰珠算技术等级鉴定工作先进单位,这对于珠算协会的发展和促进我省珠算科学事业的蓬勃发展具有重要意义。我代表黑龙江省科协对会议的召开表示热烈祝贺！向出席会议的全体同志并通过大家向全省广大珠算科学工作者致以亲切的问候！     

双8051CPU分时主从机技术在窄间隙埋弧焊过程中的应用

由于双丝窄间隙埋弧焊系统状态参数多，单片ＣＰＵ已无法适应于整个控制系统的要求。为了解决此技术难题，本文介绍一种采用双８０５１ＣＰＵ利用分时主－从机处理技术，实施了该系统的微机自动化控制。双８０５１ＣＰＵ一片为从机，另一片为从机。两ＣＰＵ实施各自的处理功能，并利用串行口进行通讯联络。实验结果表明，双８０５１ＣＰＵ分时主－从机技术较好地解决了系统所提出的技术要求，实现微机化控制的系统性能优良，并获得了广泛的推广应用，经济效益显著。     

多分支中性受体的合成及αω-二羧酸阴离子识别研究

Two new multi-armed neutral receptors 1 and 2 containing thiourea and amide groups were synthesized by simple steps in good yields. Receptors 1 and 2 have a better selectivity and higher association constants for malonate anion than other anions examined by the present work. In particular, distinct color changes were observed upon addition of dicarboxylate anions to the solution of 1 in DMSO. The UV-Vis and fluorescence spectra data indicate that a 1 ： 2 stoichiometry complex was formed between compound 1 or 2 and dicarboxylate anions of shorter carbon chain, and a 1 ： 1 stoichiometry complex was formed between compound 1 or 2 and dicarboxylate anions of longer carbon chain through hydrogen bonding interactions.     

Study on Syntheses and Anti-bacterial Activities of Some New Transition Metal Complexes with Schiff Base Ligand Containing Pyridine and Amide Moieties

Several new transition metal complexes using Schiff base containing pyridine and amide moieties (N, N′-bis(β-salicylaliminoethyl)-2, 6-pyridinedicarboxylic amide, H4L) as the ligand have been prepared. Their compositions and structures are corroborated by elemental analysis, IR, UV, ^1H NMR, DTA-TG and molar conductivity data.Their anti-bacterial activities have been studied by microcalorimetry. The result shows that the ligand and all complexes are potential anti-bacteria reagent and their inhibitory capacities are concentration-depended. The Mn complex has the strongest inhibitory capacity.     

Selective Synthesis of [2＋2] Macrocyclic Schiff Bases from Chiral 1,4-Diamines

[2＋2] macrocyclic Schiff bases of three kinds have been synthesized from chiral 1,4-diamines by use of different methods. Macrocyclic Schiff bases 1a-1c have been selectively obtained based on a non-templated dilution method from chiral 1,4-diamines a-c and dialdehyde DA1, whereas macrocycles 2a-2c have been selectively produced from reaction of diamines a-c and dialdehyde DA2 in the presence of boric acid as templates. Macrocyclic Schiff bases 3a-3c have been afforded in high selectivity from diamines a-c and dialdehyde DA3 by means of sodium-template. All the titled compounds have been confirmed by ^1H NMR and ESI-MS analyses.     

Amide-based Fluorescent Macrocyclic Anion Receptors

Introduction Interest in the selective recognition and sensing of anionic species continues to attract the attention of su-pramolecular chemistry community.1 The importance of anions in chemical and biological process can not be underestimated. It is well known that in nature neutral proteins bind anions only via hydrogen bonding interac-tions.2 Several anion receptors have been constructed from five-membered heterocycle,3 amide,4 (thio) urea,5 since these groups form relatively strong NHanio…     

激光微探针质谱及其应用

激光应用于质谱的研究开始于六十年代初,Honig等首先报道了第一台激光质谱仪的研制。以后通过对激光离子化机理、激光脉冲时间、光束功率和直径对离子化效率、初始离子能量分布影响的研究,Fenner等研制出激光微探针质谱仪。该仪器用带Q开关的红宝石激光器作为离子化光源,激光的脉冲     

基于苯并噻唑单元的Fe~(3+)荧光探针的合成及细胞成像应用研究

设计并合成了新型基于苯并噻唑的荧光探针L1和L2。通过荧光光谱滴定实验研究了其在DMSO/H_2O(1∶1,V/V,HEPES,p H=7.2)中对Li~+,Na~+,K~+,Ag~+,Cu~(2+),Ni~(2+),Zn~(2+),Mn~(2+),Cd~(2+),Hg~(2+),Co~(2+),Mg~(2+),Ca~(2+),Ba~(2+),Al~(3+),Cr~(3+),Fe~(3+)等不同金属离子的选择性识别能力,结果表明,探针对Fe~(3+)表现出较高的选择性,并与Fe~(3+)形成1∶1配合物,络合常数为(2.36×10~3)。其他常见金属离子的存在对铁离子引起的荧光淬灭无影响。探针L2还被用于活细胞中铁离子的检测。     

连续流动法测定卷烟纸和造纸法再造烟叶中碳酸钙含量

取卷烟纸或造纸法再造烟叶细条(约0.5cm×2.5cm)样品0.500g,与0.5mol·L~(-1)盐酸溶液4.5 mL反应完全,加入95.5 mL水,混匀后过滤,于滤液中加入5g活性碳,振荡30min,过滤,收集滤液。采用连续流动法通过碘酸钾、碘化钾与样品溶液中剩余H+的显色反应来计算剩余H+的含量,从而推算样品中碳酸钙的含量。结果表明:(1)碳酸钙的线性范围为5.007~30.042mg;(2)方法的检出限(3s)为0.11mg;(3)连续测定6次所得结果的相对标准偏差为0.34%~0.86%;(4)加标回收率为96.6%~103%。方法的测定值和电位滴定法的测定值基本相符,但与离子色谱法所测结果之间有一定差异。