Synthesis,Structure Analysis,and Antitumor Activity of （R）-2,4-Dioxo-5-fluoro-l-[1-（methoxycarbonyl） Ethylaminocarbonylmethyl]-1,2,3,4-tetrahydropyrimidine

A new dipeptide compound, （R）-2,4-dioxo-5-fluoro-1-[1-（methoxycarbonyl） ethylaminocarbonylmethyl]-1,2,3, 4-tetrahydropyrimidine （5-FUAPM）, has been synthesized and identified by means of elemental analysis, IR, ^1H NMR and ^13C NMR spectra. The single crystal of compound 5-FUAPMoDMF was also obtained and characterized by DSC-TGA techniques. The crystal belongs to orthorhombic space group P212121 with the cell parameters： a= 0.4740（7） nm, b= 1.923（3） nm, c= 1.9229 nm, a=β=y=90°, V= 1.753 nm^3, Z=4, Dc= 1.312 g/cm^3, Mr=346.32, F（000）=728 and u=0.111 mm^-1. The final R and wR are 0.1378 and 0.2862, respectively. The result of the biological test showed that the compound 5-FUAPM has certain antitumor activities.     

HF气相刻蚀技术及其在MEMS加速度计中的应用

本文介绍了一种用于微结构干法释放的HF气相刻蚀技术。通过调节工艺参数(包括腔体压力,HF流量,乙醇流量,氮气流量)研究其对二氧化硅刻蚀速率和均匀性的影响,得到刻蚀速率在500魡/min左右,均匀性5%左右的工艺菜单。该技术运用于MEMS加速度计中,成功实现了梳齿结构和质量块的无粘连释放。     

Microwave Solvothermal Synthesis,Crystal Structures and in Vitro Antitumor Activities of Di-n-butyltin Piperonylate with a Sn_4O_4 Ladder Framework

A two-dimensional supramolecular compound di-n-butyltin piperonylate, {(μ_3-O)(μ_2-OMe)(n-Bu_2Sn)_2[O_2CAr(C_2H_4O)]}_2 constructed by hydrogen bonds with a Sn_4O_4 ladder-like framework, was obtained by the microwave-assisted solvothermal reaction of di-n-butyltin oxide precursor with the piperonylic acid in methanol environments. The composite was characterized by elemental analysis and IR(~1H, ~(13)C and ~(119)Sn) NMR spectra. The compound crystallizes in monoclinic system, space group P21/n with a = 13.3690(12), b = 14.1442(14), c = 16.4022(16) ?, β = 107.191(6)°, V = 2963.0(5) ?~3, Z = 2, Dc = 1.520 g/cm~3, F(000) = 1368, μ = 1.719 mm~(-1), Mo Kα radiation(λ = 0.71073 ?), the final R = 0.0495 and w R = 0.1260 for 6780 observed reflections with I 2σ(I). Its X-ray crystallography diffraction analyses show a Sn_4O_4 ladder-like skeleton, in which two endocyclic tin and one exo tin atoms are bonded to the μ_3-O atom. In addition, one endocyclic tin and one exo tin atoms are respectively bonded to the μ_2-O atom from methanol. The ladder-like molecule has a three-ring fused skeleton, which is almost coplanar. The endocyclic and exocyclic tin atoms were all five-coordinated with distorted trigonal bipyramidal geometry. The antitumor activity showed that the compound had higher activities than cisplatin in HT-29, HepG2, MCF-7, KB and A549 cell line in vitro.     

基于SOA架构的新一代计费清算系统设计与实现

新一代计费清算系统引入SOA，打破原有封闭式架构，实现计费清算服务可复用。通过构建统-N务接入框架，降低遗留系统接入新架构的接入成本，为计费清算系统集中化运营运维提供了技术保障。     

宽带射频功放晶体管非线性输出电容研究

分析了GaN(氮化镓)HEMT(高电子迁移率晶体管)非线性输出电容Cout与宽带功放效率的关系。通过建立非线性电路模型分析得出,利用Cout控制漏极端电压电流波形能减轻对谐波阻抗的精确要求,使高效率阻抗区域扩大化,从而使宽带功放匹配变为可能。选用GaN HEMT器件设计2~3 GHz频段射频功率放大器,实测结果为该放大器最高漏极效率(DE)为81.7%,功率附加效率(PAE)78.3%,功率为40.75 dBm。在1 GHz带宽内PAE也可达65%以上。实测结果验证了原理分析的可靠性,提出的方法不仅可用于宽带GaN功率放大器设计,对其他类型的微波功放设计同样有借鉴作用。     

电磁搅拌作用下激光熔池电磁场、温度场和流场的数值模拟

建立了描述电磁搅拌辅助激光熔凝过程的电磁场和流场的三维数学模型,采用有限元和有限体积结合的方法实现激光熔池中电磁场与温度场及流场的耦合模拟分析,研究了电磁场对激光熔池流场与温度场的影响。结果表明,电磁力在水平面上呈周向分布,切向电磁力的大小从熔池边缘到中心递减;在旋转磁场的作用下,熔池内温度略有降低,温度梯度减小;熔池内液体趋向旋转运动,速度场分布与电磁力相似;熔池纵向环流增加,使熔池内的熔体对流加剧,有利于传热,加快冷却;激励电流大小对电磁场和熔池流场有明显影响。为激光加工提供理论参考。     

视频内容安全保障新方法探索与实践——视频基因管控系统

在网络安全形势日趋严峻的今天,互联网视频网站、广播电视网络等视频播出系统遭受网络攻击已经成为现实.提出了一种可在传输线路上实时保障视频内容安全的新方法——视频基因管控系统,可部署在播出系统出口线路上,作为独立、隐形的视频内容安检闸门,确保广电前端网络或互联网视频网站被恶意攻击并控制时,违规内容仍无法输出到网络上.系统还可部署在承载网的传输线路上,为多屏融合情形下的碎片化视频内容监管、内容版权保护提供基于传输线路的实时解决方法.     

面向融合网络的广电双向接入网入侵检测系统

针对广电接入网边界缺乏安全防护措施的现状,提出一种面向融合网络的广电接入网入侵检测系统,并实例化为SunGnet703,可检测并实时阻断进出接入网边界的各类网络攻击.系统具有“非配合”部署、高可靠性运行、“隐形”确保自身安全、全维数据分析4个特点,可为广电接入网边界提供一种简便易行的安全防护方法和实际系统.