基于级联随机共振与APSO算法相结合的信号检测方法

针对随机共振方法以系统的参数和噪声强度的匹配为研究背景的局限性,为解决级联双稳系统参数的合理选取的问题及克服自适应随机共振单参数优化的不足之处,提出了一种基于级联随机共振与自适应粒子群(APSO)算法相结合的方法。该方法以系统的输出信噪比为优化目标函数,采用自适应粒子群算法较强的全局搜索能力和粒子(待优化参数)的多样性,对级联双稳态随机共振的级联系统参数进行同步优化,使系统处于最佳随机共振工作状态。仿真结果表明,该方法可以提高输出信噪比及算法的收敛速度,实现良好的检测效果。     

基于G-LCOP算法的自适应方向图控制

自适应方向图控制是阵列信号处理的关键,这里在广义线性约束正交投影算法（G-LCOP,Generalized Linearly Constrained Orthogonal Projection）基础上进行了自适应方向图控制算法（APC,Adaptive Pattern Control）的研究,G-LCOP算法能够在降秩的同时保留原有线性约束,并在此基础上增加了新的线性约束,并将静态权矢量向优化的干扰子空间投影,从而形成一种新的广义线性约束正交投影自适应方向图控制算法（G-LCOP-APC,Generalized Linearly Constrained Orthogonal Projection Adaptive Pattern Control）,用新权矢量得到的自适应方向图能够较好地逼近期望的静态方向图,有效地压制干扰和噪声。     

Application of colloidal palladium nanoparticles for labeling in electron microscopy

The application of palladium nanoparticles as electron-dense markers for labeling in both transmission and scanning electron microscopy requires their conjugation to a specific protein. The conjugation protocol described here includes the dihydrolipoic acid (DHLA) capping of Pd nanoparticles (8 nm equivalent diameter) and their subsequent covalent attachment to functional protein molecules such as streptavidin, protein A, or avidin. The single-step reaction was mediated using the cross-linking agent ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC). The final Pd conjugates were fully functional, as demonstrated by labeling of ultrathin resin sections of either bovine serum albumin or secretory granules of the salivary gland isolated from the partially fed female Ixodes ricinus tick. The results of bovine serum labeling were quantified, statistically evaluated, and compared with results obtained using commercially available gold particle conjugates (10 nm diameter). The highest values of labeling density were achieved using both streptavidin-Pd (106 ± 7 particles/μm2) and protein A-Au conjugates (130 ± 18 particles/μm2) compared to a commercial streptavidin-Au (66 ± 16 particles/μm2) and protein A-Pd conjugates (70 ± 11 particles/μm2). The concentrations of both DHLA and EDC, pH during conjugation, and finally thorough washing away of unbound proteins crucially influenced conjugation.     

Electron image series reconstruction of twin interfaces in InP superlattice nanowires

The twin interface structure in twinning superlattice InP nanowires with zincblende structure has been investigated using electron exit wavefunction restoration from focal series images recorded on an aberration-corrected transmission electron microscope. By comparing the exit wavefunction phase with simulations from model structures, it was possible to determine the twin structure to be the ortho type with preserved In-P bonding order across the interface. The bending of the thin nanowires away from the intended 110 axis could be estimated locally from the calculated diffraction pattern, and this parameter was successfully taken into account in the simulations.     

Simulation of photoelectron spectra using the reflection principle in combination with unrestricted excitation ADC2 to assess the accuracy of excited-state calculations

The gas-phase photoelectron spectra of ethene, formaldehyde, formic acid and difluoromethane are simulated using the reflection principle and the unrestricted second-order algebraic diagrammatic construction [UADC(2)] scheme of the polarization propagator for the computation of the vertical-excited states of the cations at the equilibrium geometry of the parent neutral molecule. Comparison is made with experimental spectra and the established highly accurate ionization IP-ADC(3) theory to gain insight into the accuracy and applicability of recently developed excitation UADC schemes. Within UADC(2), we distinguish between the strict and extended schemes UADC(2)-s and UADC(2)-x. While the latter approach is found to slightly underestimate the experimental photoelectron spectra by 0.3 eV and can thus be regarded as a reliable scheme within the limits of the applied reflection principle and the underlying approximations, the UADC(2)-s scheme tends to overestimate the excitation energies by about 0.5 eV. Time-dependent density functional theory is also applied in combination with the standard B3LYP xc functional and turns out to be a useful computational tool for the simulation of the photoelectron spectra of the studied species.     

Novel covalent bond in proteins: calculations on model systems question the bond stability

We have investigated the sulfilimine covalent link between methionine (Met) and lysine (Lys), recently identified in collagen IV (R. Vanacore, A.-J. L. Ham, M. Voehler, C. R. Sanders, T. P. Conrads, T. D. Veenstra, K. B. Sharpless, P. E. Dawson, B. G. Hudson, Science 2009, 325, 1230), and have explored its stability with respect to both the redox processes and UV radiation by means of advanced computational methods. We have concluded that the bond should be present in a protonated state, (-NH=S-)(+). The bond is characterized by a relatively high standard reduction potential, that is, the bond should not be stable in a typical cell environment; if the sulfilimine bond exists (as suggested by the experiment) then the bond has to be supported by the protein environment. The sulfilimine bond then destabilizes the protein structure with respect to the alternative tertiary structure. We discuss conditions under which the bond could be formed as well as other possible structural arrangements consistent with the Met-Lys stoichiometry; some of the alternative bond motifs are more thermodynamically stable than the sulfilimine bond. We suggest that the character of the Met-Lys contact could be approached via NEXAFS spectroscopy. Finally, we show that the protonation brings photostability to the sulfilimine bond.     

幂硬化材料平面应变条件下的复应力函数解

本文导出应力函数的几个特解，以便增加对幂硬化材料平面应变问题的认识     

The First Total Synthesis of Triprenylquinone and Hydroquinones

Marine natural products have received much attention for their attractive structural features and biological activities1. Since the isolation of the moritoside, about 10 related triprenylquinones and hydroquinones were isolated. Some of these natural products exhibit interesting biological effects including inhibit cell division of fertilized starfish eggs2 and anti-HIV3. Triprenylquinone and hydroquinones 1, 2 and 3 were recently isolated from endemic nudibranch Leminda millecra collected i…     

一种非高斯噪声中未知参数的信号的检测方法

研究了非高斯噪声中具有未知参数的信号的渐进最优检测，应用非高斯噪声中线性模型信号以及随机信号的Rao检验，导出了Rao检测的解析式，并与广义似然比检验的性能做比较。仿真结果表明，该检测器性能大大优于传统的能量检测器和高斯噪声假设下的广义似然比检测器。     

POSITRON ANNIHILATION WITH VACANCIES IN THIN SURFACE LAYER OF As HEAVILY DOPED Si

The lifetime spectroscopy of slow positron accelerated with linear accelerator and pulse punch system was first used to analyze the vacancies in the thin surface layer of silicon heavily doped with arsenic. The results demonstrated that no mono-vacancy was detected to support the arsenic-vacancy complex models for explaining the electrical deactivation mechanism of arsenic-heavily-doped silicon.