混合二烃基二氯化锡与水杨醛缩苯胺类Schiff减配合物的…

由混合二烃基二氯化锡与水杨醛缩苯胺类Ｓｃｈｉｆｆ碱反应，合成了２４种新的有机锡配合物。经元素分析、ＮＭＲ“ＴＧ－ＤＳＣ测定和Ｘ射线粉末衍射分析，确定有１４种有机锡与Ｓｃｈｉｆｆ碱的１：１配合物，１０种是１：２配合物。配体是以酚羟基氧原子与锡原子配位，摩尔电导率测定表明这些配合物均为非电解质。     

P570-萃淋树脂分离稀土元素的研究 Ⅰ、静态分配系数的测定

本文报导了P507-萃淋树脂的合成方法。测定了稀土元素在P507树脂与盐酸溶液间的静态分配系数。并且讨论了盐酸浓度、温度、聚合物中P507的浓度及氯化铵量对静态分配系数的影响。     

脂质体导向给药治疗缺血性心脏病的可行性研究(Ⅰ)

本工作在离体大鼠心肌细胞、离体灌流大鼠和家兔心脏模型上,对脂质体作为药物载体导向治疗缺血性心脏病的可行性进行了基础研究。结果表明,心肌细胞可通过融合(Fusion)、内吞(Endocytosis)、吸附(Adsorption)和磷脂分子交换(Exchange)四种方式与脂质体相互作用。细胞摄取脂质体的方式主要取决于脂质体的理化性质。缺氧改变了心肌细胞对脂质体的摄取方式并增加其摄取能力。缺血心肌组织对脂质体、尤其对带正电荷脂质体的摄取显著增加。其摄取量按序为缺血-再灌注区>梗塞边缘区>非缺血区>梗塞区。上述实验结果提示:脂质体作为药物载体可将药物输送到缺血心肌组织和心肌细胞内。     

3-(水杨酰肼)-丁基-2-酮肟和两个镍的酮肟配合物的合成和晶体结构

合成了3-(水杨酰肼)-丁基-2-酮肟H₂L(1，C₁₁H₁₃N₃O₃)和2个镍的3-(水杨酰肼)-丁基-2-酮肟化合物[Ni(HL)(CH₃COO^-)(C₅H₅N)₂](2)和[Ni(HL)₂]·2C₃H₇NO（3）。化合物1晶体属单斜晶系，空间群为P2₁/n，晶体学参数为：a=0.451 87(2) nm，b=2.086 8(1) nm，c=1.224 48(9) nm，β=94.974(3)°，V=1.150 3(1) nm³，Z=4，D_c=1.358 g·cm^-3，μ=0.101 mm^-1，F(000)=496，R=0.0435，wR=0.142 5。化合物2晶体属单斜晶系，空间群为P2₁/n，晶体学参数为：a=1.362 39(8) nm，b=1.345 37(6) nm，c=1.438 54(7) nm，β=113.138(3)°，V=2.424 6(2) nm³，Z=4，D_c=1.398 g·cm^-3，μ=0.843mm^-1，F(000)=1 064，R=0.042 4，wR=0.116 6。化合物3晶体属单斜晶系，空间群为P2₁/c，晶体学参数为：a=1.104 22(7) nm，b=2.860 1(1) nm，c=1.114 13(7)nm，β=114.589(5)°，V=3.199 5(3) nm³，Z=4，D_c=1.398 g·cm^-3，μ=0.667 mm^-1，F(000)=1 416，R=0.057 6，wR=0.1535。在化合物1晶体中，酮肟分子之间通过分子间氢键形成二维网状结构。在化合物2中，每个镍(Ⅱ)离子由1个3-(水杨酰肼)-丁基-2-酮肟的2个氮原子和1个氧原子，2个吡啶分子中的2个氮原子和1个乙酸根中的1个氧原子形成畸变的NiN₄O₂八面体配位构型，存在分子内氢键O-H(肟)…O(乙酸根)和O-H(酚)…N(酰肼)。在化合物3晶体中，每个镍(Ⅱ)离子由2个3-(水杨酰肼)-丁基-2-酮肟的4个氮原子和2个氧原子配位，形成畸变的NiN₄O₂八面体配位构型。晶体中存在O-H…O和O-H…N两种分子内氢键和O-H…O分子间氢键。     

混合溶剂火焰原子吸收法直接测定原油中的镍

混合溶剂火焰原子吸收法直接测定原油中的镍刘广东袁存光张丙华刘文钦（石油大学（华东），山东东营２５７０６２）彭力（中国石油天然气总公司环保处，北京１００７２４）关键词原油，混合溶剂，无机盐标准，原子吸收法，镍测定原油中，微量元素镍、钒、铁、铜的存在对...     

SDS/n－C5H11OH/n－C7H16/H2O体系中W/O－BI微乳液界面电性质

In the system of SDS/n-C5H11OH/n-C7H16/H2O with the weight ratio of SDS/n-C5H11OH/H2O system at5.0/47.5/47.5, the upper phase of the system was W/O microemulsion, and the lower phase was the bicontinuous microemulsion. When the n-heptane content was less than 1%, with the increase of the n-heptane content, the capacitance (Co, Cod) in the upper phase (W/O) dropped, the capacitance (CB1, CBld) in the lower phase (BI) raised. At the same time, the W/O-BI inteffacial potential (ΔE), capacitance (Ci), and charge-transfer current (ict) decreased.After the n-heptane content reached 1%, with the increase of the n-heptane content, ΔE, Ci and ict demonstrated no significant change.     

Synthesis and Asymmetric Enantioselective Addition of Chiral Polybinaphthyl and Polybinaphthol I.igands

Four chiral polymers P-1, P-2, P-3 and P-4 were synthesized by the polymerization of （S）-2,2＇-dioctoxy-1,1＇- binaphthyl-6,6＇-boronic acid （S-M-3） with （S）-6,6＇-dibromo-1,1＇-binaphthol （S-M-1）, （R）-6,6＇-dibromo-1,1＇- binaphthol （R-M-1）, （S）-3,3＇-diiodo-1,1＇-binaphthol （S-M-2） and （R）-3,3＇-diiodo-1,1＇-binaphthol （R-M-2） under Pd-catalyzed Suzuki reaction, respectively. All four polymers can show good solubility in some common solvents due to the nonplanarity of the polymers in the main chain backbone and flexible alkyl groups in the side chain. The analysis results indicate that specific rotation and circular dichroism （CD） spectral signals of the alternative S-S chiral polymers P-1 and P-3 are larger than those of S-R chiral polymers P-2 and P-4, but their UV-Vis and fluorescence spectra are almost similar. The results of asymmetric enantioselectivity of four polymers for diethylzinc addition to benzaldehyde indicate that catalytically active center is （R） or （S）-1, 1＇-binaphthol moieties.     

N－乙酰皮考林酰肼合镍配合物的合成和晶体结构

合成了N－乙酰皮考林酰肼α-(C_5H_4N)CONHNHCOCH_3(简写为HL）及其镍配合 物Ni~(II)L_2·1.5CH_3OH·H_2O(C_(17.5)H_(24-)N_6NiO_(6.5))。配合物晶体属 于单斜晶系，空间群为P2_1/c，a = 1.5393 (1) nm, b = 0.80278(7) nm, c = 1. 8245(1) nm, β = 105.985(3)°, V=2.1674(3)nm~3, Z = 4, F(000) = 1004, R = 0.0503。在配合物中，镍（II）原子呈扭曲的N_4O_2八面体配位构型，晶体通 过分子间氢健作用形成一维的无限链状结构。红外光谱表明，配体在形成配合物后 , v (C=O)和v（C＝N）红移，电子光谱表明存在π-π~*和d-π~*的跃迁。     

高分子路易斯酸催化剂—阳离子交换树脂四氯化锡复合物

大孔强酸性聚苯乙烯系阳离子交换树脂与SnCl_4在CS_2中反应可生成一种稳定的高分子路易斯酸催化剂.其制备简单、易分离.这种催化剂不怕水,对酯化、缩醛、缩酮、醚化及付氏烷基化反应具有较好的催化作用,且催化性能稳定,至少可重复使用10次.     

16-脱氢孕烯醇酮醋酸酯的环境友好合成法

Instead of environmentally toxic chromium oxidant, singlet oxygen generated photcchemically was used as environmentally friendly and benign oxidizing agent to accomplish the transformation of pseudodiosgenin diacetate to diosone efficiently in a low toxic and less expensive solvent acetone. Accordingly 16-dehydropregnenolone acetate(16-DPA), an important intermediate for preparation of steroidal drugs, was prepared in good yield (75%) when photoreaction was run in acetone/acetic anhydride/pyridine system. The mild reaction condition as well as simple and environmentally friendly process made the method commercially viable and important for production of 16-DPA in industrial scale.