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Bouferrache B. Krim G. Mejdoub N. Quanjer P.H. Freville M. Libert J.P. 《IEEE transactions on bio-medical engineering》1998,45(11):1305-1312
Dynamic modeling of lung C18O diffusion is used to measure the C18O transfer factor (TLco) of 14 newborns aged 1-4 mo. The model equation is based on the alveolar fractions of C18O and on changing alveolar ventilation induced by the rebreathing conditions. The model does not involve the volume of the rebreathing bag which is usually needed when applying rebreathing technique add which is a source of error. The equation is discretized and solved for recorded data obtained with equipment adapted to use in newborns. A least-square parameter calculation technique is applied to estimate TLco. Results show a strong relationship between this index and the biometrical ones and confirm those found in the literature featuring that the measurement duration can be considerably shortened 相似文献
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Bouferrache B. Krim G. Leke A. Freville M. Libert J.-P. 《IEEE transactions on bio-medical engineering》2001,48(7):834-838
Helium dilution maneuver is used to determine the functional residual capacity (FRC) 14 newborns ages 1-5 mo. The model equation describes the changing alveolar fractions of He and the ventilation promoted by a rebreathing procedure that does not exceed 40 s. The model does not involve the volume of the rebreathing bag usually needed when applying rebreathing technique and which is a source of error. The equation is discretized and solved for recorded data obtained with equipment adapted to newborns. Results show a strong relationship between FRC and the biometrical indexes, and confirm those found in the literature featuring that the measurement duration of FRC can be considerably shortened. 相似文献
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