Explorative study of costs, effects and savings of screening for female fragile X premutation and full mutation carriers in the general population

OBJECTIVE: Evaluation of the costs, effects and savings of three strategies for female fragile X premutation and full mutation carrier screening in the general population. METHODS: We calculated the costs, effects and savings by using a general model for prenatal, preconceptional, and school carrier screening. Assumptions were based on literature data, expert opinions, prices and tariffs. RESULTS: Prenatal screening will detect most carriers and will lead to the highest number of avoided fragile X syndrome patients. The costs per detected carrier are quite similar for all screening programmes (around USD 45,000). All screening strategies have a favourable cost-savings balance (USD 14 million for prenatal screening, USD 9 million for preconceptional screening and USD 2 million for school screening). CONCLUSIONS: From an economic point of view, there is no obstacle to fragile X screening. The decision to screen or not can (and should) therefore concentrate on discussion of medical, social, psychological and ethical considerations.     

Inhomogeneous fluids of colloidal hard dumbbells: fundamental measure theory and Monte Carlo simulations

Recently, a density functional theory for hard particles with shape anisotropy was developed, the extended deconvolution fundamental measure theory (edFMT). We apply edFMT to hard dumbbells, arguably the simplest non-convex shape and readily available experimentally in the form of colloids. We obtain good agreement between edFMT and Monte Carlo simulations for fluids of dumbbells in a slit and for the same system under gravity. This indicates that edFMT can be successfully applied to nearly all colloidal shapes, not just for the convex shapes for which edFMT was originally derived. A theory, such as edFMT, that allows a fast and general way of mapping the phase behavior of anisotropic colloids, can act as a useful guide for the design of colloidal shapes for various applications.     

Determination of Copper,Iron, and Zinc in Crayfish (Procambrus clarkii) by Inductively Coupled Plasma–Optical Emission Spectrometry

Inductively coupled plasma–optical emission spectrometry was used to determine copper, iron, and zinc in both whole Crayfish and tail meat of crayfish from selected areas in southwestern Louisiana. Also included was a comparison between male and female crayfish. Results showed no significant difference between male and female crayfish and individuals from different sites. Iron was approximately four times greater in concentration for whole crayfish compared with tail meat.     

Die Spannung des Quecksilberdampfes bei niedrigen Temperaturen

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Zur Bestimmung des Zuckers

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Über jodometrische Mikrobestimmung von JO3′ und Cr2O7″ in kleinen Konzentrationen Verwendung von Silberkatalyse

Analytical and Bioanalytical Chemistry -     

Apparate

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Extraktionsapparate

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