含能破片引爆带壳炸药过程的数值模拟

将引爆模拟战斗部等效为带铝壳炸药,设计了一种新型含能破片作为毁伤元,利用非线性有限元LS -DYNA软件对该含能破片侵彻、引爆带壳炸药的作用过程进行了数值模拟。用“升降法”得到了该“含能破片”对不同盖板厚度带壳炸药的引爆速度,同时与普通破片引爆同规格带壳炸药进行了对比,并进行了实验验证。结果表明,通过控制含能破片的撞击速度和含能物质的延迟起爆时间,可有效引爆盖板厚度为8~16mm的带铝壳炸药。

     

新型缓变锥型PCF结构接口耦合损耗特性

提出一种新型的缓变锥型光纤接口器件。该接口器件是一个长度为150 mm左右的缓变锥型光子晶体光纤。利用有限元方法对模场直径差别较大的不同光纤进行拼接时的损耗问题进行研究。研究结果表明：在模场直径分别为9 m和10.4 m的光纤之间加入锥型光纤后可以有效降低耦合损耗,并且在不同波长下耦合损耗都维持在一个较低水平。因此,该接口器件能够实现光纤拼接时物理结构的过渡和不同模场直径的转换,从而使拼接损耗降到最低。     

中能电子成像仪探头的设计

利用小孔成像原理对中能电子成像仪探头的机械结构进行了设计,为保证探头单元暴露于外辐射带辐射环境12年的总剂量小于5 krad,确定其壳体厚度为约3 mm的铜,探头的角分辨率为20;根据带电粒子在硅中的能量损失规律对探测器进行了防质子污染设计,确定了探测器厚度为1000 m,其屏蔽层厚度为10 m等效硅。最后对设计探头的质子污染率进行了计算,结果表明该中能电子成像仪探头的设计满足外辐射带空间中能电子探测的需求,为中能电子成像仪的研制奠定了基础。     

X箍缩三维数值模拟

利用FOI-PERFECT程序对X箍缩进行了3D数值模拟研究,给出了X箍缩的物理图像和动力学过程,探讨了Z箍缩中出现磁重联的可能性,并指出如果双丝Z箍缩中能够出现磁重联,那么X箍缩是更有利于磁重联出现的位形,并且,X箍缩中出现多重X射线暴的一个可能原因是z轴上多个位置出现磁重联。     

低约束试件断裂韧性测试方法研究进展 1)

低约束试件断裂韧性测试对油气管道安全运营具有重要意义。本文回顾了低约束试件断裂韧性测试方法及发展过程,介绍了裂纹尖端张开位 移(crack tip opening displacement, CTOD)和J积分等常用断裂韧性表征参数,并对断裂韧性测试中应力强度因子、J积分塑性因子、J积分与CTOD转换因子、裂纹尺寸测量方法、数 字图像相关方法等关键问题进行对比分析,总结需要深入研究的问题,为低约束试件断裂韧性测试发展提供一定依据。     

面向"一带一路"的工程教育国际化新体系研究与实践1)

"一带一路"战略为深化我国与沿线国家的教育交流合作提供了重要契机,也为我国的新工科人才培养体系的理论研究与教育实践开拓了新视野,提出了新挑战。在以新技术、新业态、新模式、新产业为代表的新经济蓬勃发展的大背景下,对工程科技人才提出了更高要求。建设具有新理念、新结构、新体系、新质量、新模式的新工科,迫切需要借助国际化加快工程人才教育体系的改革创新。构建面向"一带一路"的工程教育国际化新体系,面向新工科人才培养,密切结合"一带一路"沿线各国工科人才培养的实际情况,以工程力学、航空航天工程、机械工程等专业的国际化联合培养为抓手,深入研究面向新工科建设的"一带一路"工程教育国际化新体系。     

Rutin Inhibits Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation by Inducing Autophagy and Modulating PI3K/ATK Signaling

Atherosclerosis (AS) is one of the leading causes of death among the elderly, and is primarily caused by foam cell generation and macrophage inflammation. Rutin is an anti-inflammatory, anti-oxidant, anti-allergic, and antiviral flavonoid molecule, known to have anti-atherosclerotic and autophagy-inducing properties, but its biological mechanism remains poorly understood. In this study, we uncovered that rutin could suppress the generation of inflammatory factors and reactive oxygen species (ROS) in ox-LDL-induced M2 macrophages and enhance their polarization. Moreover, rutin could decrease foam cell production, as shown by oil red O staining. In addition, rutin could increase the number of autophagosomes and the LC3II/I ratio, while lowering p62 expression. Furthermore, rutin could significantly inhibit the PI3K/ATK signaling pathway. In summary, rutin inhibits ox-LDL-mediated macrophage inflammation and foam cell formation by inducing autophagy and modulating PI3K/ATK signaling, showing potential in treating atherosclerosis.     

A Novel Gelatin-Based Sustained-Release Molluscicide for Control of the Invasive Agricultural Pest and Disease Vector Pomacea canaliculata

Pomacea canaliculata, one of the 100 most destructive invasive species in the world, and it is an important intermediate host of Angiostrongylus cantonensis. The molluscicides in current use are an effective method for controlling snails. However, most molluscicides have no slow-release effect and are toxic to nontarget organisms. Thus, these molluscicides cannot be used on a large scale to effectively act on snails. In this study, gelatin, a safe and nontoxic substance, was combined with sustained-release molluscicide and was found to reduce the toxicity of niclosamide to nontarget organisms. We assessed the effects of gelatin and molluscicide in controlling P. canaliculata snails and eggs. The results demonstrated that the niclosamide retention time with 1.0% and 1.5% gelatin sustained-release agents reached 20 days. Additionally, the mortality rate of P. canaliculata and their eggs increased as the concentration of the niclosamide sustained-release agents increased. The adult mortality rate of P. canaliculata reached 50% after the snails were exposed to gelatin with 0.1 mg/L niclosamide for 48 h. The hatching rate of P. canaliculata was only 28.5% of the normal group after the treatment was applied. The sustained-release molluscicide at this concentration was less toxic to zebrafish, which means that this molluscicide can increase the safety of niclosamide to control P. canaliculata in aquatic environments. In this study, we explored the safety of using niclosamide sustained-release agents with gelatin against P. canaliculata. The results suggest that gelatin is an ideal sustained-release agent that can provide a foundation for subsequent improvements in control of P. canaliculata.     

Structural and Bonding Properties of AlnC4-/0 (n=2-4) Clusters:Anion Photoelectron Spectroscopy and Theoretical Calculations

We measured the photoelectron spectra of AlnC4-(n=2-4) clusters by using size-selected anion photoelectron spectroscopy.The structures of AlnC4-/0 (n=2-4) clust...     

Carbene-catalyzed activation of cyclopropylcarbaldehydes for mannich reaction and δ-lactam formation: remote enantioselecitvity control and dynamic kinetic asymmetric transformation

An N-heterocyclic carbene(NHC)-catalyzed enantioselective Mannich reaction of the remote γ-carbon of cyclopropylcarbaldehydes is disclosed for the first time. Diastereo-and enantiomerically enriched multicyclic δ-lactam compound is afforded as the main product from 8 possible stereo-specific isomers through dynamic kinetic asymmetric transformation(DYKAT) processes. Multiple chiral functional molecules can be afforded from the lactam products through simple protocols with retentions of the optical purities.