A New Cytotoxic Acetogenin from the Seeds of Annona squamosa

A New Annonaceous acetogenin,squamostolide(1),was isolated from the seeds of Annona squamosa.Its structure was elucidated based on spectroscopic methods and comparison with known compounds.It is the first example of Annonaceous acetogenin with each of the two ends of the aliphatic chain bearing a γ-lactone.Thenew compound exhibited cytotoxic activity in vitro against bel-7402 and CNE2 human tumor cell lines.     

一个耦合系统自由边界问题的整体古典解

§ 1　ＩｎｔｒｏｄｕｃｔｉｏｎＩｎｔｈｉｓｐａｐｅｒｗｅｄｉｓｃｕｓｓｔｈｅｇｌｏｂａｌｃｌａｓｓｉｃａｌｓｏｌｕｔｉｏｎｏｆａｍｕｌｔｉｄｉｍｅｎｓｉｏｎａｌｑｕａｓｉｓｔａｔｉｏｎａｒｙｐｒｏｂｌｅｍ .Ｔｈｅｐｒｏｂｌｅｍｃｏｍｅｓｆｒｏｍｔｈｅｄｉｓｃｕｓｓｉｏｎｏｆａｇｒｏｗｔｈｍｏｄｅｌｏｆｓｅｌｆｍａｉｎｔａｉｎｉｎｇｐｒｏｔｏｃｅｌｌ(ｓｅｅ [1— 3])ｉｎｍｕｌｔｉｄｉｍｅｎｓｉｏｎａｌｃａｓｅ .Ｔｈｅｐｒｏｔｏｃｅｌｌｃａｎｂｅｖｉｓｕａｌｉｚｅｄａｓｈａｖｉｎｇａｐｏｒｏｕｓｓｔ…     

原子的吸收光谱和发射光谱的演示

介绍了利用光学多道分析仪和投影仪在课堂上实时演示原子的吸收光谱和发射光谱的实验方法。     

复方单硝酸异山梨酯-阿司匹林双缓释微丸胶囊的研制(Ⅱ)

以乙基纤维素、丙烯酸树脂Ⅱ和丙烯酸树脂Ⅲ为骨架材料分别制备单硝酸异山梨酯和阿司匹林混合骨架缓释微丸，并通过包薄膜衣进一步控制药物的释放。通过测定微丸的释放度对处方工艺进行评价，选择最佳微丸灌装胶囊．胶囊中两种药物均达到良好的缓释效果。符合中国药典对缓释制剂的要求．其体外释放过程同时符合Higuchi方程和一级释药方程，R^2值均在0．995以上。     

KrF准分子激光激发掺锗光纤折射率扰动的非线性过程

本文采用了一种简单的功率监测法,观察了KrF准分子激光对掺锗光纤折射率影响的非线性过程。观察到子纤芯折射率扰动过程中非稳定现象、饱和现象和折射率扰动的非线性。     

超软X射线流气式正比计数管

介绍了一种用于测量183～933eV超软X射线的圆柱形、侧窗式、流气式正比计数管,工作气体是0.11MPa的P-10气体或氦气-丙烷混合气体。计数管内径为φ25mm,直径为φ0.3mm的入射窗是由厚度80～90μgcm~2聚乙烯甲醛制成的。该计数管的特点:(1)薄窗,对软X射线透过率高。(2)流气式,工作寿命长。(3)能量分辨率好。(4)计数率高(1×10~(14)个/s)。(5)可测能区宽(0.183～10keV)。(6)可以方便更换窗膜材料、厚度及窗口直径。近几年来该计数管已经为高强度低能X光源提供较好监测。     

The Existence of Periodic Orbits for Higher Dimensional Autonomous Systemswith Small Perturbations

ＴｈｅＥｘｉｓｔｅｎｃｅｏｆＰｅｒｉｏｄｉｃＯｒｂｉｔｓｆｏｒＨｉｇｈｅｒＤｉｍｅｎｓｉｏｎａｌＡｕｔｏｎｏｍｏｕｓＳｙｓｔｅｍｓｗｉｔｈＳｍａｌｌＰｅｒｔｕｒｂａｔｉｏｎｓＪｉａｎｇＬｉｑｉｎｇ（蒋里强）；ＺｈｏｕＹｉ（周毅）；ＦａｎＹｅ（范晔）（...     

Viscosity solution theory of a class of nonlinear degenerate parabolic equations II. Lipschitz continuity of free boundary

In [1] we construct a unique bounded Hölder continuous viscosity solution for the nonlinear PDEs with the evolutionp-Laplacian equation and its anisotropic version as typical examples. In this part, we investigate the Lipschitz continuity of the free boundary of viscosity solution and its asymptotic spherical symmetricity, however, this result does not include the anisotropic case.This research is supported by the National Natural Sciences Foundation of China.     

Poly(phenylene vinylene)‐based copolymers containing 3,7‐phenothiazylene and 2,6‐pyridylene chromophores: Fluorescence sensors for acids,metal ions,and oxidation

A novel copolymer, poly(N‐hexyl‐3,7‐phenothiazylene‐1,2‐ethenylene‐2,6‐pyridylene‐1,2‐ethenylene) ( P3 ), containing N‐hexyl‐3,7‐phenothiazylene and 2,6‐pyridylene chromophores was synthesized to investigate the effect of protonation, metal complexation, and chemical oxidation on its absorption and photoluminescence (PL). Poly(N‐hexyl‐3,8‐iminodibenzyl‐1,2‐ethenylene‐1,3‐phenylene‐1,2‐ethenylene) and poly(N‐hexyl‐3,7‐phenothiazylene‐1,2‐ethenylene‐1,3‐phenylene‐1,2‐ethenylene) ( P2 ), consisting of 1,3‐divinylbenzene alternated with N‐hexyl‐3,8‐iminodibenzyl and N‐hexyl‐3,7‐phenothiazylene, respectively, were also prepared for comparison. Electrochemical investigations revealed that P3 exhibited lower band gaps (2.34 eV) due to alternating donor and acceptor conjugated units (push–pull structure). The absorption and PL spectral variations of P3 were easily manipulated by protonation, metal chelation, and chemical oxidation. P3 displayed significant bathochromic shifts when protonated with trifluoroacetic acid in chloroform. The complexation of P3 with Fe³⁺ led to a significant absorption change and fluorescence quenching, and this implied the coordination of ferric ions with the 2,6‐pyridylene groups in the backbone. Moreover, both phenothiazylene‐containing P2 and P3 showed conspicuous PL quenching with a slight redshift when oxidized with NOBF₄. © 2004 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 42: 1272–1284, 2004     

17N+197Au反应中碎片与中子的符合测量

在3?3?.4MeV/u ¹⁷N束轰击¹⁹⁷Au靶产生的反应中,利用放置于不同角度组合的17个中子探测器(4°—83°)和14个半导体望远镜(2.3°—9.0°)对反应产物碎片与中子进行了符合测量.经对所得实验角分布积分得到Z=3—6元素的同位素产额分布.在参加者-旁观者模型框架下,采用¹⁷N原子核内部的不同密度分布计算了同位素产额分布并与实验数据做比较.