MRI-negative rotator cuff tears

We report two cases of rotator cuff tear in which the T(2)-weighted MRI signal was negative at the first examination, but positive by the second examination without any changes in symptoms. Many authors have reported on correlations between the MRI and operative findings of rotator cuff tears. However, MRI findings, history of symptoms and operative findings in our patients suggest that there was a discrepancy between symptoms and MRI findings dependent on the period from the injury. Operative findings also indicate that intratendinous tears might have occurred first in these patients then progressed to partial or full thickness tears over time. We concluded that physicians should keep rotator cuff pathology in mind even in patients whose MRI findings are negative but symptoms of rotator cuff tear persist.     

Pulsatile entrance flow in curved pipes: effect of various parameters

This paper presents the results of an experimental study on the developing pulsatile flow in curved pipes with a long, straight pipe upstream. In order to examine the dependence of flow-field development on the governing parameters, LDV measurements were conducted systematically for six cases of flow, where the Womersley number α was varied from 5.5 to 18, the mean Dean number D _m was 200 and 300, the flow rate ratio η was 0.5 and 1, and the curvature radius ratio Rc was 10 and 30. Peculiar flow phenomena, such as flow reversal for all values of α and a depression in the axial velocity profile for α = 10, were analyzed by decomposing the axial velocity into a time-mean and a varying component, as well as by obtaining the bias of their profiles. The velocity distributions abruptly change with the phase at turn angles Ω of 15–30°, corresponding to the nondimensional axial length z′ ≅ 1–2 from the bend entrance, and their development along the pipe axis is the most complicated for the flow at a moderate α of 10 and large η of 1. The entrance length in the case of pulsatile flow is shorter than that for steady flow with the same flow rate as the maximum pulsatile flow rate.     

Phosphorus-carbon bond formation by lewis Acid catalyzed/mediated addition of silylphosphines

Triethylaluminum-catalyzed/mediated addition of a silylphosphine to aldehydes and epoxides is described. Organophosphines containing a silyloxy group at the alpha- or beta-position on the alkyl substituent are successfully prepared in good yields.     

Experimental investigation on turbulent flow through a circular-sectioned 180° bend

The steady, developing turbulent flow in a circular-sectioned 180° bend has been investigated. The bend had a radius of 104 mm and a curvature radius ratio of 4.0 with long, straight upstream and downstream pipes. Measurements of the longitudinal, radial and circumferential components of mean velocity, and corresponding components of the Reynolds stress were obtained with a hot wire anemometer at a Reynolds number of 6×10⁴ and at various longitudinal stations. The velocity fields of the primary and secondary flows and the Reynolds stresses were illustrated in the form of contour map or vector diagram. Moreover, the mean quantities characterizing the bend flow, i.e., the deflection of the primary flow in the cross section, the intensity of the secondary flow and the turbulence energy, were shown in a graphic form against the longitudinal distances. In the section upstream from a bend angle of about 60°, both the flows through the 180° and the 90° bend are closely similar in their behavior. In the section from the bend angle of 90°, the high-velocity regions, however, occur near the upper and lower walls as a result of strong secondary flow and the turbulence with high level emerges in the central region of the bend. Just behind the bend exit, an additional pair of vortices appears in the outer part of the cross section owing to the transverse pressure difference. In the downstream tangent, the flow returns slowly to the proper flow in a straight pipe, but it needs a longer distance for recovery than in the 90° bend. Received: 23 April 1998/Accepted: 24 April 1999     

Synthesis,Structures, and Thermal Properties of Symmetric and Janus “Lantern Cage” Siloxanes

Symmetric and asymmetric (Janus-type) new “lantern cage” siloxanes (PhSiO_1.5)₄(Me₂SiO)₄(RSiO_1.5)₄ (R=Ph or iBu) were synthesized through reaction of all-cis-[PhSi(OSiMe₂Br)O]₄ with all-cis-[RSi(OH)O]₄ (R=Ph or iBu). These precursors were obtained by facile two or three-step reactions from commercially available compounds. The spectroscopic properties of the resulting products were fully characterized and they showed high thermal stability and sublimation without decomposition. The crystal structures clearly indicated that the internal vacancy volumes of the lantern cages are considerably larger than that of octaphenylsilsesquioxane (PhSiO_1.5)₈. DFT calculations of the lantern cage showed a distinctly different electronic state from that of octasilsesquioxane. These results suggest that lantern cage siloxanes have a characteristic “field” in the molecule.     

Total Synthesis of the 7,10‐Epimer of the Proposed Structure of Amphidinolide N,Part I: Synthesis of the C1–C13 Subunit

Amphidinolide N, the structure of which has been recently revised, is a 26‐membered macrolide featuring allyl epoxide and tetrahydropyran moieties with 13 chiral centers. Due to its challenging structure and extraordinary potent cytotoxicity, amphidinolide N is a highly attractive target of total synthesis. During our total synthesis studies of the 7,10‐epimer of the proposed structure of amphidinolide N, we have synthesized the C1–C13 subunit enantio‐ and diastereoselectively. Key reactions include an l ‐proline catalyzed enantioselective intramolecular aldol reaction, Evans aldol reaction, Sharpless asymmetric epoxidation and Tamao–Fleming oxidation. To aid late‐stage manipulations, we also developed the 4‐(N‐benzyloxycarbonyl‐N‐methylamino)butyryl group as a novel ester protective group for the C9 alcohol.     

NUMBER CONCENTRATION, SIZE DISTRIBUTION AND FINE PARTICLE FRACTION OF TROPOSPHERIC AND STRATOSPHERIC AEROSOLS

1. Introduction The number concentration and size distribution of at-mospheric particles are the two major parameters for aerosol radiative forcing calculation, as the aerosol bur-dens affect the radiative transfer of solar and terrestrial emissions, while the size distribution of atmospheric aerosol is critical to all climatic influences (IPCC, 2001). However most measurements on the characteristics of the number-size distribution were carried out near the earth surface, with only a few exte…     

Annulenediones having quinonoid properties

Chemical and Electrochemical reductions of bisdehydro[14]- and [18]annu1ened1ones clearly revealed their quinonoid nature.