Dynamic polarization potential effects on vector analyzing powers of Li–Si elastic scattering from non-monotonic potentials

Experimental cross section (CS) and vector analyzing power (VAP) data of the ⁶Li–²⁸Si elastic scattering at 22.8 MeV are analyzed in the coupled-channels (CC) and coupled discretized continuum channels (CDCC) methods. Non-monotonic (NM) ⁶Li and α potentials of microscopic origin are employed, respectively, in the CC calculations and to generate folding potentials for the CDCC calculations. The study demonstrates that the use of central NM potentials can generate an appropriate dynamic polarization potential (DPP) required to describe both the CS and VAP   data without the necessity of renormalization. This also produces an effective spin–orbit (SO) potential to account for the iT₁₁$i{T}_{11}$ data without the requirement of an additional static SO potential at the incident energy considered.     

Explicit,periodic and dispersive optical soliton solutions to the generalized nonlinear Schrödinger dynamical equation with higher order dispersion and cubic-quintic nonlinear terms

In this article, the nonlinear Schrödinger equation with higher order dispersion and nonlinear terms have been discussed analytically using extended Fan sub-equation method. The results hold numerous traveling wave solutions like optical, bright, dark, explicit, periodic and combined wave solutions with the aid of five parameters that are of key importance in elucidating some physical circumstance.     

Computational soliton solutions to $$$$-dimensional generalised Kadomtsev–Petviashvili and $$(2+1)$$(2+1)-dimensional Gardner–Kadomtsev–Petviashvili models and their applications

In this paper, we present a formalism to generate a family of interior solutions to the Einstein–Maxwell system of equations for a spherically symmetric relativistic charged fluid sphere matched to the exterior Reissner–Nordström space–time. By reducing the Einstein–Maxwell system to a recurrence relation with variable rational coefficients, we show that it is possible to obtain closed-form solutions for a specific range of model parameters. A large class of solutions obtained previously are shown to be contained in our general class of solutions. We also analyse the physical viability of our new class of solutions.     

Improved Interfacial Ion Migration and Deposition through the Chain-Liquid Synergistic Effect by a Carboxylated Hydrogel Electrolyte for Stable Zinc Metal Anodes

The large-scale applicability of Zn-metal anodes is severely impeded by the issues such as the dendrite growth, complicated hydrogen evolution, and uncontrollable passivation reaction. Herein, a negatively charged carboxylated double-network hydrogel electrolyte (Gelatin/Sodium alginate-acetate, denoted as Gel/SA-acetate) has been developed to stabilize the interfacial electrochemistry, which restructures a type of Zn²⁺ ion solvent sheath optimized via a chain-liquid synergistic effect. New hydrogen bonds are reconstructed with water molecules by the zincophilic functional groups, and directional migration of hydrated Zn²⁺ ions is therefore induced. Concomitantly, the robust chemical bonding of such hydrogel layers to the Zn slab exhibits a desirable anti-catalytic effect, thereby greatly diminishing the water activity and eliminating side reactions. Subsequently, a symmetric cell using the Gel/SA-acetate electrolyte demonstrates a reversible plating/stripping performance for 1580 h, and an asymmetric cell reaches a state-of-the-art runtime of 5600 h with a high average Coulombic efficiency of 99.9 %. The resultant zinc ion hybrid capacitors deliver exceptional properties including the capacity retention of 98.5 % over 15000 cycles, energy density of 236.8 Wh kg⁻¹, and high mechanical adaptability. This work is expected to pave a new avenue for the development of novel hydrogel electrolytes towards safe and stable Zn anodes.     

Antiparasitic activities of bimetallic N-heterocyclic carbene gold(I) complexes with ferrocene ligands: Relevance of chlorido and phosphino ligands

Gold(I) complexes carrying imidazole-2-ylidene ligands and ferrocene substituents were prepared. Their activities against protozoal Leishmania major and Toxoplasma gondii parasites were analyzed. Certain gold(I) complexes with chlorido and 1,1′-bis(triphenylphosphino)ferrocene ligands revealed promising antiparasitic effects. The new chlorido complexes 5b and 5c showed high activities against T. gondii tachyzoites and L. major promastigotes while the new ferrocene-bridged bis-gold(I) complexes 8a and 8b were particularly active against L. major amastigotes and considerably selective as to toxicity results from Vero cells and macrophages.     

Mathematical Analysis of SIR Epidemic Model with Piecewise Infection Rate and Control Strategies

The limitation of contact between susceptible and infected individuals plays an important role in decreasing the transmission of infectious diseases. Prevention and control strategies contribute to minimizing the transmission rate. In this paper, we propose SIR epidemic model with delayed control strategies, in which delay describes the response and effect time. We study the dynamic properties of the epidemic model from three aspects: steady states, stability and bifurcation. By eliminating the existence of limit cycles, we establish the global stability of the endemic equilibrium, when the delay is ignored. Further, we find that the delayed effect on the infection rate does not affect the stability of the disease-free equilibrium, but it can destabilize the endemic equilibrium and bring Hopf bifurcation. Theoretical results show that the prevention and control strategies can effectively reduce the final number of infected individuals in the population. Numerical results corroborate the theoretical ones.     

Progress of Metal-Based Anticancer Chemotherapeutic Agents in Last two Decades and their Comprehensive Biological (DNA/RNA Binding,Cleavage and Cytotoxicity Activity) Studies

During last two decades, there has been an enormous growth in the discovery of innovative active inorganic anticancer complexes (exerting remarkable cytotoxicity at sub micro-molar levels) derived from myriad ligand scaffolds, mainly acting on cancerous vs healthy cells by either halting or inhibiting their uncontrolled growth. The phenomenal success of cisplatin to treat numerous forms of solid malignancies has placed metal-based drugs to the forefront of treatment strategies against cancers. More than 10,000 platinum anticancer complexes have been developed during the past 40 years, but only five drugs have been approved for usage in humans while ten more complexes are currently undergoing clinical trials. Most of the compounds have failed either at R&D stages or in preclinical trails. This has led to extensive investigations by researchers of medicinal chemistry, including our group to design and prepare tailored 3d-metallo-drugs and organotin(IV) compounds from some naturally occurring bioactive compounds, such as amino-acids, peptides, chromone derivatives and NSAID's etc. that were used either alone or in cocktail combination, capable of specifically targeting DNA, lnc RNAs and proteins. Furthermore, 3d-metal ions such as copper, cobalt and zinc etc. incorporated in these ligand framework are biocompatible and induce a unique multi-modal mechanism of cytotoxic action involving angiogenesis, ROS-induced DNA damage, apoptosis by p53 mitochondrial genes and caspases etc. The results observed a positive correlation between the binding affinity of complexes with DNA (as quantified by intrinsic binding constant values) and their cytotoxic behavior. Complexes with high DNA binding propensity were typically lethal against a diverse panel of malignant cell types compared to normal cells.