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851.
Wei Cheng Ming Ji Xiaodan Li Jinwei Ren Fuling Yin Leen van Ofwegen Siwang Yu Xiaoguang Chen Wenhan Lin 《Tetrahedron》2017,73(17):2518-2528
Chemical investigation of the gorgonian coral Junceella fragilis resulted in the isolation of a new norditerpenoid fragilolide A (1), sixteen new briarane diterpenoids fragilolides B-Q (2–17), together with frajunolides H and N, and three known norcembranoids scabrolide D, sinuleptolide and 5-epi-sinuleptolide. The structures of new compounds were determined on the basis of extensive spectroscopic analysis, including the experimental and calculated ECD data and single-crystal X-ray diffraction for the configurational assignments. The structure of fragilolide A featured an unprecedented 4,13- and 7,11-fused tetracyclic norcembranoid, while the biogenetic relationships of the briarane analogues were postulated. Frajunolide H exerted significant inhibition against a panel of tumor cell lines, and six briarane diterpenoids (3, 6, 8, 12, 16, and frajunolide N) exhibited the inhibitory effects against the HBeAg express of hepatitis B virus in HepAD38 cells. In addition, sinuleptolide and 5-epi-sinuleptolide exerted the effects to inhibit NO production in RAW264.7 macrophage cells, in addition to the activation of ARE and the inhibition of NF-κB expression. 相似文献
852.
Qing-Dong Wang Jin-Ming Yang Dong Fang Jiangmeng Ren Bu-Bing Zeng 《Tetrahedron letters》2017,58(30):2877-2880
An efficient iodine-catalyzed chemoselective 3-formylation of free (N–H) and N-substituted indoles was achieved by using hexamethylenetetramine (HMTA) in the presence of activated carbon under air atmosphere. This new method could provide 3-formylindoles in moderate to excellent yields with fairly short reaction times. Moreover, this catalytic formylation of indoles procedure can be applied to gram-scale synthesis. 相似文献
853.
Jaromíra Chýlková Markéta Tomášková Lenka Janíková Renáta Šelešovská Tomáš Navrátil Petra Chudobová 《Chemical Papers》2017,71(6):1047-1054
A sensitive voltammetric method for the determination of pyrogallol (PY) was developed employing a boron-doped diamond electrode (BDDE). The composition of the supporting electrolyte was investigated during the development of the methodology. Linear sweep voltammetry (LSV) under the optimized experimental conditions was applied for PY determination with a limit of detection and limit of quantification of 0.85 and 2.82 μmol L?1, respectively. These values are satisfactory for application to real samples. The usability of this method for the quantification of pyrogallol was in range from 2.82 to 296.00 μmol L?1. Finally, the developed method was successfully used for the analysis of real samples of biodiesel produced from rapeseed oil and its blend with diesel fuel. Samples of biodiesel and biodiesel blends were analyzed directly in an electrochemical cell, while samples with very low concentrations of PY in biodiesel were extracted with water using the proposed simple and fast process. 相似文献
854.
Haiyang Fan Lifeng Chen Huihui Sun Hualei Wang Qinghai Liu Yuhong Ren Dongzhi Wei 《Chemical Papers》2017,71(10):1985-1992
This study aimed at developing an efficient biotransformation process for phenylacetic acid production from phenylacetonitrile by using recombinant Escherichia coli M15 harboring a double mutant MG nitrilase (I113M/Y199G) from Burkholderia cenocepacia J2315. A yield of 2310 U/mL nitrilase was obtained by fermentation after the optimization of cultivation conditions, with a specific activity of 64 U/mg dcw. The MG nitrilase showed high substrate tolerance and completely hydrolyzed 100 mM phenylacetonitrile in 30 min under optimal conditions. To alleviate substrate inhibition, periodic or continuous batch-feeding of substrate was used during the biotransformation. Up to 164 g/L substrate was completely hydrolyzed in 9 h with continuous batch-feeding using resting cells, corresponding to 400 U/mL of nitrilase activity, and leading to production of 163.4 g/L phenylacetic acid. The hydrolysis process has potential application for phenylacetic acid production on a large scale. 相似文献
855.
Miao Cheng Zongyi Qin Yuanyu Chen Jiaming Liu Zichu Ren 《Cellulose (London, England)》2017,24(8):3243-3254
A facile and efficient approach to prepare carboxylated cellulose nanocrystals (CCNCs) is presented through a novel one-step hydrothermal procedure by using a mixed acid system of hydrochloric acid and nitric acid (HCl/HNO3). The as-prepared cellulose nanoparticles were characterized by scanning electron microscopy, wide angle X-ray diffraction, conductometric titrations, Fourier transform infrared spectrometry and thermal gravimetric analysis. The results showed that the combination of the mixed acid and hydrothermal reaction can speed up the process of CCNC preparation, and then high quality of the product could be obtained at relatively low acid concentration. It is found that the addition of nitric acid could not only promote the conversion of surface groups on the cellulose nanocrystals (CNCs), but also have significant influences on the yield, particle size and microstructure of CNCs. For the volume ratio of HCl/HNO3 of 7:3, the as-prepared CCNCs exhibited the largest length to diameter ratio and narrowest dimension distributions as well as maximum degree of oxidation of 0.12. In addition, high dispersion stability for the CCNCs could be observed due to the existence of negative carboxyl groups. This approach based on one-step oxidative carboxylation greatly simplified the preparation of CCNCs with high yield and high crystallinity under mild hydrothermal condition. 相似文献
856.
857.
858.
Antibacterial membranes based on chitosan and quaternary ammonium salts modified nanocrystalline cellulose 下载免费PDF全文
Ying Liu Mei Li Mingyu Qiao Xuehong Ren Tung‐Shi Huang Gisela Buschle‐Diller 《先进技术聚合物》2017,28(12):1629-1635
Etherification of nanocrystalline cellulose (NCC) with three kinds of quaternary ammonium salts epoxypropyltrimethylammonium chloride, N,N‐dimethyl‐N‐dodecyl‐N‐(1,2‐epoxypropyl) ammonium chloride (DMDEPAC), and N,N‐dimethyl‐N‐octadecyl‐N‐(1,2‐epoxypropyl) ammonium chloride (DMOEPAC) was successfully performed via a nucleophilic addition reaction. The synthesized DMDEPAC and DMOEPAC were characterized by nuclear magnetic resonance. The modified NCC particles, NCC epoxypropyltrimethylammonium chloride, NCC‐DMDEPAC, and NCC‐DMOEPAC, were characterized by energy dispersive spectrometer. Nanocomposite films based on chitosan (CS) containing quaternary ammonium salts modified NCC were prepared with nanoparticle loadings of 5.0, 7.5, and 10.0%, respectively. The effect of nanoparticle content on the tensile strength of composite films was studied. The results indicated that the films with 5.0% nanoparticle loading exhibited the biggest increase in tensile strength. Surface morphology, smoothness, and antibacterial properties of composite films containing 5% modified NCC were also studied. CS/NCC‐DMDEPAC‐5.0 and CS/NCC‐DMOEPAC‐5.0 displayed excellent biocidal abilities against both Gram‐positive Staphylococcus aureus (ATCC 6538) and Gram‐negative Escherichia coli O157:H7 (ATCC 43895). The bio‐based nanocomposite films with increased mechanical strength and excellent antibacterial properties show great potential as food packaging materials. Copyright © 2017 John Wiley & Sons, Ltd. 相似文献
859.
基于甲醛、苯和二氧化硫在纳米Ti3CeY2O11上的催化发光有交叉敏感现象,在3个波长处分别确定甲醛、苯和二氧化硫浓度与催化发光信号强度的响应关系,再依据发光信号强度的叠加性特征即可获取甲醛、苯和二氧化硫的准确浓度,据此建立了同时测定空气中甲醛、苯和二氧化硫的新方法.3个分析波长分别为420、535和680 nm,敏感材料表面温度为280℃,载气流速为130 mL/min.本方法对甲醛、苯和二氧化硫的检出限(3σ)分别为0.04、0.05和0.10 mg/m3,线性范围分别为0.08~75.60 mg/m3、0.10~101.40 mg/m3和0.30~115.00 mg/m3, 回收率分别为96.4%~103.7%、97.8%~102.5%和97.2%~103.3%.常见共存物,如乙醛、甲苯、硫化氢、氨、甲醇、乙醇和二氧化碳等不干扰测定.连续200 h通浓度均为50 mg/m3的甲醛、苯和二氧化硫混合气体,发光强度的相对偏差≤2%,表明此纳米级复合氧化物对甲醛、苯和二氧化硫的敏感性的寿命长.本方法充分利用了交叉敏感现象,可以实现空气中甲醛、苯和二氧化硫的在线分析. 相似文献
860.
Wei Ren Weiren Cheng Guan Wang Ye Liu 《Journal of polymer science. Part A, Polymer chemistry》2017,55(4):632-639
Effective antimicrobial polymers have been attracting more interests because of the low propensity to cause drug-resistant microorganisms. The recent progresses in antimicrobial polymers are updated according to the action approaches, that is, antimicrobial polymers with free mobility or fixed on surfaces, respectively. Free antimicrobial polymers kill pathogens majorly via electrostatic interaction followed by disruption of the cell membranes; strong antimicrobial activity of primary/secondary amines, new chemical units, and peptides without facial amphiphilicity are highlighted; and the dependences on amphiphilicity, topology, and self-assembly profiles are summarized. Antimicrobial polymers fixed on surfaces kill pathogens via interaction with the cell membranes of pathogens via electrostatic or hydrophobic interaction; approaches to antimicrobial surfaces based on covalently grafting, anchoring, and bulk-mixing of polymers are summarized; and new designs of sustainable antimicrobial surfaces and hydrogels are highlighted. Deep biology understanding and development strategies of materials are suggested for the future. © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2017 , 55, 632–639 相似文献