An integrated microfluidic device for influenza and other genetic analyses

An integrated microfluidic device capable of performing a variety of genetic assays has been developed as a step towards building systems for widespread dissemination. The device integrates fluidic and thermal components such as heaters, temperature sensors, and addressable valves to control two nanoliter reactors in series followed by an electrophoretic separation. This combination of components is suitable for a variety of genetic analyses. As an example, we have successfully identified sequence-specific hemagglutinin A subtype for the A/LA/1/87 strain of influenza virus. The device uses a compact design and mass production technologies, making it an attractive platform for a variety of widely disseminated applications.     

Spiro-configured bifluorenes: highly efficient emitter for UV organic light-emitting device and host material for red electrophosphorescence

[structure: see text] Remarkable UV OLED devices using novel spiro-configured bifluorenes as UV emitters have been successfully achieved with external quantum efficiencies up to 2.6-3.1% and emission wavelengths as short as 370 nm. In addition, these large-gap materials have been shown to be effective hosts for red phosphorescent emitters in phosphorescent OLEDs. This result represents the first example that pure hydrocarbon molecules can serve as an efficient host for red electrophosphorescence devices.     

Preparation and characterization of silver/TiO2 composite hollow spheres

Silver-coated poly(methyl acrylic acid) (PSA) core-shell colloid particles were prepared by an in situ chemical reduction method. Crystalline silver/titania composite hollow spheres were obtained by coating the as-prepared PSA/silver particles with an amorphous titania layer and subsequently calcining in Ar atmosphere. SEM and TEM investigation indicated that the size of the as-prepared PSA/silver and PSA/silver/TiO(2) core-shell particles and silver/titania composite hollow particles was fairly uniform and the wall thickness of the hollow spheres was in the range of 40-80 nm. UV-vis absorption spectra were recorded to investigate their optical properties.     

Electrochemical reduction and voltammetric determination of metronidazole at a nanomaterial thin film coated glassy carbon electrode

Simple and sensitive electrochemical method for the determination of metronidazole, based on a nanostructured film coated glassy carbon electrode (GCE), is described. Multi-walled carbon nanotubes (MWNT) was dispersed into water in the presence of a hydrophobic surfactant to give very stable and homogeneous MWNT suspension, and a MWNT-film coated GCE was achieved via evaporating solvent. Metronidazole yields a well-defined reduction peak whose potential is −0.71 V at the MWNT-film coated GCE in pH 9.0 Britton-Robinson buffer. Compared with bare GCE, the MWNT-film modified GCE significantly enhances the reduction peak current of metronidazole. All the experimental parameters were optimized for the determination of metronidazole. The detection limit is 6×10⁻⁹ mol/l at 2 min accumulation. This method has been successfully used to determine metronidazole in the drugs. Furthermore, results obtained by the proposed method have been compared with spectrophotometric method.     

Preparation of mesoporous aluminophosphate using poly(amido amine) as template

Mesoporous aluminophosphate was prepared by using G4.0 poly(amido amine)dendrimer as a template and characterized by Fourier transform infrared spectrometer (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM) and N₂ adsorption/desorption methods. Results show that the title compound exhibits a typical mesoporous structure with the average pore size from 5 to 8 nm. The formation mechanism of the nanoporous structure using dendrimer as a template was also discussed. __________ Translated from Journal of Fujian Normal University (Natural Science Edition), 2007, 23(2): 67–70 [译自: 福建师范大学学报 (自然科学版)]     

微波照射合成不对称1，4－二氢吡啶的研究

微波照射合成不对称１，４－二氢吡啶的研究张雅文，沈宗旋，潘备，杨海康，陆新华，陆澄容（苏州大学化学系苏州２１５００６）关键词缩合，二氢吡啶，微波Ｈａｎｔｚｓｃｈ合成是制备１，４－二氢吡啶的经典方法。这一合成的改进方法之一是３－氨基巴豆酸酯与醛和乙酰乙...     

Electrothermal volatilization of aluminum as 1-phenyl-3-methyl-4-benzoylpyrazolone[5] chelate for gaseous sample introduction in ICP-AES

Based on gaseous compound introduction as 1-phenyl-3-methyl-4-benzoylpyrazolone[5](PMBP) chelate of aluminum by electrothermal vaporization in ICP-AES, a method for determination of trace aluminum was developed. Trace aluminum was vaporized at temperature of 1000 degrees C, and the vaporization behavior of aluminum chelate was detailedly investigated. Under the optimum conditions, the detection limit of aluminum was 0.6 ng ml(-1), and the relative standard deviation for 0.1 mug ml(-1) aluminum was 4.7% (n=8). The proposed method was applied to the determination of trace aluminum in rice flour reference materials, and the results well agreed with the reference values.     

镉—溴化物—罗丹明B高灵敏显色反应的研究：离心光度法测定镉

本研究了一个高灵敏的测定镉的方法，离心光度法，该体系络合物λｍａｘ＝５６０ｎｍ，表观摩尔吸系数ε５６０＝５．０６×１０＾８Ｌ．ｍｏｌ＾－１．ｃｍ＾－１，Ｃｄ＾２＋浓度０．１０×１０＾－２－１．０×１０＾－２μｇ／１０ｍＬ呈线性关系，本法已用于血清和水中痕量镉的测定，探讨了高灵敏的显色反应机理。     

N－取代硫代磷酰胺二乙酯合成新方法的研究

以ＰＥＧ作相转移催化剂，在无机碱（Ｋ＿２ＣＯ＿３或Ｎａ＿２ＣＯ＿３）存在下，用乙基氯化物（Ｏ，Ｏ－二乙基硫代磷酰氯）与不同的胺反应，合成了六种Ｎ－取代硫代磷酰胺二乙酯，其结构经ＩＲ、ＮＭＲ和元素分析证实。     

弹性体型聚氨酯和聚碳酸酯共混物的形态结构

用ＤＳＣ、ＷＡＸＤ和ＳＡＸＳ研究了溶液共混的弹性体型聚氨酯（ＰＵ）／聚碳酸酯（ＰＣ）共混物的结构。结果表明，ＰＵ／ＰＣ为部分相容体系；共混过程中，溶剂ＤＭＦ的诱导作用使ＰＣ形成结晶，其长周期与ＰＵ硬段形成微相的长周期相近