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41.
Arijit Das Eric Soehnlen Stephan Woods Ravi Hegde Amanda Henry Arne Gericke Soumitra Basu 《Journal of nanoparticle research》2011,13(12):6283-6290
We report a novel gold nanobioconjugate system that achieves targeted delivery of the small molecule drug doxorubicin to endothelial
cells using anti-VEGFR-2 antibody conjugated gold nanoparticles (GNPs). The reported nanobioconjugate system combines the
inherent ability of GNPs to undergo high levels of derivatization with the precision of antibody recognition of a cell surface
antigen. Transmission electron microscopy (TEM) and surface-enhanced Raman spectroscopy (SERS) confirmed intracellular presence
of the GNPs. Using a VEGFR-2 expressing cell line and a cell line that is negative for the receptor, in combination with competition
assay we established the cell specific targeted delivery of the nanobioconjugate. The nanobioconjugate system described here
may have potential drug delivery applications for antiangiogenic cancer therapy. 相似文献
42.
Far-infrared-absorption spectroscopy is used to investigate the low-frequency (相似文献
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D. Habs O. Kester T. Sieber H. Bongers S. Emhofer P. Reiter P.G. Thirolf G. Bollen J. Aystö O. Forstner H. Ravn T. Nilsson M. Oinonen H. Simon J. Cederkall F. Ames P. Schmidt G. Huber L. Liljeby O. Skeppstedt K.G. Rensfelt F. Wenander B. Jonson G. Nyman R. von Hahn H. Podlech R. Repnow C. Gund D. Schwalm A. Schempp K.-U. Kühnel C. Welsch U. Ratzinger G. Walter A. Huck K. Kruglov M. Huyse P. Van den Bergh P. Van Duppen L. Weissman A.C. Shotter A.N. Ostrowski T. Davinson P.J. Woods J. Cub A. Richter G. Schrieder 《Hyperfine Interactions》2000,129(1-4):43-66
The Radioactive Beam Experiment REX-ISOLDE [1–3] is a pilot experiment at ISOLDE (CERN) testing the new concept of post acceleration
of radioactive ion beams by using charge breeding of the ions in a high charge state ion source and the efficient acceleration
of the highly charged ions in a short LINAC using modern ion accelerator structures. In order to prepare the ions for the
experiments singly charged radioactive ions from the on-line mass separator ISOLDE will be cooled and bunched in a Penning
trap, charge bred in an electron beam ion source (EBIS) and finally accelerated in the LINAC. The LINAC consists of a radiofrequency
quadrupole (RFQ) accelerator, which accelerates the ions up to 0.3 MeV/u, an interdigital H-type (IH) structure with a final
energy between 1.1 and 1.2 MeV/u and three seven gap resonators, which allow the variation of the final energy. With an energy
of the radioactive beams between 0.8 MeV/u and 2.2 MeV/u a wide range of experiments in the field of nuclear spectroscopy,
astrophysics and solid state physics will be addressed by REX-ISOLDE.
This revised version was published online in July 2006 with corrections to the Cover Date. 相似文献
45.
Maged Khalil Robert J. Woods Donald F. Weaver Vedene H. Smith 《Journal of computational chemistry》1991,12(5):584-593
The recent NMDO/M modification and parameterization of the MNDO molecular orbital method has been used to analyze intermolecular hydrogen bonding between amino acids and water, and intramolecular hydrogen bonding in monosaccharides. The results have been compared to AM1 calculations on the same systems. The MNDO/M calculations gave values which were similar to ab initio calculations with respect to the intermolecular interactions, but yielded significantly poorer results for the intramolecular interactions. The AM1 procedure performed better on the intramolecular interactions than the MNDO/M procedure, but frequently provided unfavorable three-centered hydrogen bonding geometries for the intermolecular interactions. 相似文献
46.
D. Seweryniak P. J. Woods B. Blank M. P. Carpenter T. Davinson S. J. Freeman J. Grres A. Heinz R. V. F. Janssens H. Mahmud T. L. Khoo Z. Liu G. Mukherjee E. Rehm F. Sarazin J. Shergur M. Shawcross S. Sinha A. Woehr 《Physics letters. [Part B]》2004,590(3-4):170-175
The fusion–evaporation reaction 10B(12C, 2n) was used to make the first observation of in-beam γ decays from the astrophysically important nucleus 20Na, lying adjacent to the proton drip-line. All states below the proton threshold in 20Na were populated and identified in the experiment. These include new levels, previously unresolved levels, and states located with improved energy precision. The level structure of 20Na, and its γ transitions, are compared to the mirror partner 20F measured simultaneously in this experiment. In particular, a high degree of energy stability is found for all negative parity states. These results are discussed in the context of the nuclear shell model. 相似文献
47.
Strong Direct Magnetic Coupling in a Dinuclear CoII Tetrazine Radical Single‐Molecule Magnet 下载免费PDF全文
Toby J. Woods Dr. Maria Fernanda Ballesteros‐Rivas Sergei M. Ostrovsky Andrew V. Palii Oleg S. Reu Sophia I. Klokishner Dr. Kim R. Dunbar 《Chemistry (Weinheim an der Bergstrasse, Germany)》2015,21(29):10302-10305
The ligand‐centered radical complex [(CoTPMA)2‐μ‐bmtz.?](O3SCF3)3 ? CH3CN (bmtz=3,6‐bis(2′‐pyrimidyl)‐1,2,4,5‐tetrazine, TPMA=tris‐(2‐pyridylmethyl)amine) has been synthesized from the neutral bmtz precursor. Single‐crystal X‐ray diffraction studies have confirmed the presence of the ligand‐centered radical. The CoII complex exhibits slow paramagnetic relaxation in an applied DC field with a barrier to spin reversal of 39 K. This behavior is a result of strong antiferromagnetic metal–radical coupling combined with positive axial and strong rhombic anisotropic contributions from the CoII ions. 相似文献
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F. Vanderbist P. Leleux C. Angulo E. Casarejos M. Couder M. Loiselet G. Ryckewaert P. Descouvemont M. Aliotta T. Davinson Z. Liu P. J. Woods 《The European Physical Journal A - Hadrons and Nuclei》2006,27(2):183-186
The 15O(α,α)15O elastic scattering is investigated using a 15O radioactive beam and a He gas cell limited by Mylar windows. The width of a 19Ne state at an excitation energy of 5.35MeV is measured as Γα = 3.2±1.6keV, in agreement with charge symmetry estimate. 相似文献
50.