The enthalpies of reactions 1 and 2 have been measured as ΔH(1) = ?142 ± 6 and ΔH(2) = ?112 ± 6 kJ mol?1 to determine whether thermochemical factors are a major influence in the formation of different reaction products (tcne = tetracyanoethylene). 相似文献
This review examines recent progress made in the field of modelling and predicting percutaneous absorption. It describes initial qualitative modelling and how quantitative approaches were pioneered and then developed, particularly in the context of the analysis of specific subsets of data. It then focuses on recent developments, including non-linear modelling and discusses recommendations in model construction, development and validation, suggesting that some models do not fit proposed guidelines. 相似文献
Three particles floating on a fluid surface define a triangle. The aim of this paper is to characterise the shape of the triangle, defined by two of its angles, as the three vertices are subject to a complex or turbulent motion. We consider a simple class of models for this process, involving a combination of a random strain of the fluid and Brownian motion of the particles. Following D.G. Kendall, we map the space of triangles to a sphere, whose equator corresponds to degenerate triangles with colinear vertices, with equilaterals at the poles. We map our model to a diffusion process on the surface of the sphere and find an exact solution for the shape distribution. Whereas the action of the random strain tends to make the shape of the triangles infinitely elongated, in the presence of a Brownian diffusion of the vertices, the model has an equilibrium distribution of shapes. We determine here exactly this shape distribution in the simple case where the increments of the strain are diffusive. 相似文献
