Microwave-assisted one-pot three-component polymerization of alkynes,aldehydes and amines toward amino-functionalized optoelectronic polymers

We present a microwave-assisted one-pot polymerization with three-components of alkynes, aldehydes and amines for the synthesis of new amino-functionalized optoelectronic polymers. The polymerization of diynes(1a-1c), dialdehydes(2a and 2b) and dibenzylamine catalyzed by InCl_3 was carried out smoothly within 1h under microwave radiation, yielding four soluble polymers with high molecular weights. The resulting polymers P1 and P2 could be easily dissolved in alcohol and thus utilized as the cathode interlayer for polymer solar cells(PSCs). Compared with the control device, the PSCs with P1 and P2 as the cathode interlayer and PTB7-Th:PC_(71)BM as the photoactive layer exhibited significantly higher power conversion efficiencies(PCEs) of 9.49% and 9.16%, respectively. These results suggest that this polycoupling reaction is an efficient approach to construct three-component polymers for the practical applications.     

Breaking the diffraction limit in far field by planar metalens

正Optical lens is of fundamental importance in both scientific researches and industrial communities,especially for the aspects of optical focusing and imaging.In traditional optics,the light modulation property is limited by the Rayleigh Criterion(0.61λ/NA),and therefore the development of an ideal lens that produces sub-diffraction limit focusing and imaging has been a dream of lens makers all the time.Intensive effort     

Studies toward the Synthesis of (R)‐(+)‐Harmicine

The study toward the total synthesis of (R)‐(+)‐harmicine is reported in this paper. The enantioselective synthesis of pyrrolidinone, the main backbone of of (R)‐(+)‐harmicine, has been completed by the methodology based on photo‐induced Wolff rearrangement of α‐diazo‐β‐carbonyl compounds.     

A Hexagonal Covalent Porphyrin Framework as an Efficient Support for Gold Nanoparticles toward Catalytic Reduction of 4‐Nitrophenol

A hexagonal porphyrin‐based porous organic polymer, namely, CPF‐1, was constructed by 3+2 ketoenamine condensation of the C₂‐symmetric porphyrin diamine 5,15‐bis(4‐aminophenyl)‐10,20‐diphenylporphyrin and 1,3,5‐triformylphloroglucinol. This material exhibits permanent porosity and excellent thermal and chemical stability. CPF‐1 can be employed as a superior supporting substrate to immobilize Au nanoparticles (NPs) as a result of the strong interactions between Au NPs and the CPF support. An Au@CPF‐1 hybrid was synthesized by an interfacial solution infiltration method with NaBH₄ as reducing agent. Au NPs (5 nm) grew on CPF‐1 and were distributed without aggregation. Moreover, Au@CPF‐1 exhibits superior catalytic activity compared to many other reported Au‐based catalysts for the reduction of 4‐nitrophenol in the presence of NaBH₄. In addition, Au@CPF‐1 has excellent stability and recyclability, and it can be reused for three successive reaction cycles without loss of activity. The dense distribution of phenyl rings on the channel walls of the CPF support can reasonably be regarded as the active sites that adsorb the 4‐nitrophenol molecule through hydrogen‐bonding and C?H ??? π interactions, as was confirmed by the X‐ray structure of model compound DAPP‐Benz.     

重度子痫前期产妇剖宫产布比卡因蛛网膜下腔阻滞麻醉适合剂量的临床研究

目的 探讨重度子痫前期产妇剖宫产重比重布比卡因蛛网膜下腔阻滞麻醉（腰麻）的适合剂量。方法 选取200例重度子痫前期产妇,ASAⅠ级或Ⅱ级,按随机数字表法分为4组,每组各50 例,相应各组鞘内注入布比卡因剂量分别为10、8、6 及4mg,并混合2.5μg 舒芬太尼。选择L3~4行腰硬联合穿刺,注药10min 后记录麻醉平面。根据结果进行Probit 回归分析,计算布比卡因腰麻的ED50和ED95。观察各组利多卡因及去氧肾上腺素的用量、肌松效果及患者麻醉满意度,观察各组术中并发症以及新生儿的Apgar 评分和脐动脉pH。结果 重度子痫前期患者腰麻剖宫产布比卡因ED50 和ED95分别为：6.51（95%CI：5.81～7.01）和8.68（95%CI：7.96～10.26）。4 组患者10min 后麻醉平面的差异均有统计学意义（均P＜0.05）。4mg 组利多卡因用量高于其他3组,差异有统计学意义（P＜0.05）。8mg 组、10mg 组去氧肾上腺素的用量高于其他两组,差异均有统计学意义（均P＜0.05）。低血压的发生率8mg 组、10mg 组高于其他两组,差异均有统计学意义（均P＜0.05）。４ 组间其他不良反应恶心、呕吐、寒战以及心动过缓发生率的差异无统计学意义（P＞0.05）。4 组胎儿娩出后1、5min Apgar 评分及脐动脉血气分析的结果差异均无统计学意义（均P＞0.05）。结论 重度子痫前期产妇剖宫产鞘内注入6mg 布比卡因混合2.5μg舒芬太尼,必要时辅以硬膜外麻醉,麻醉效果确切,血流动力学稳定,适合该类患者手术麻醉。