Enediynes are a novel class of naturally occurring antitumor antibiotics capable of causing DNA strand cleavage by hydrogen atom abstraction from the deoxyribose backbone. During the past decade, numerous synthetic methods have been developed to synthesize the naturally occurring and the "designed" enediynes for biomedical studies. Recently, we have succeeded in assembling the cis-enediynes 2 by a novel and high-yielding allylic rearrangement under mild reaction conditions (Eq 1).1-3 This methodology has been used to synthesize a 10-membered ring enediyne3 which exhibits DNA cleavage activity. 相似文献
Higher security and lower collision rate have always been people’s pursuits in the construction of hash functions. We consider a quantum walk where a walker is driven by two coins alternately. At each step, a message bit decides whether to swap two coins. In this way, a keyed hash function is constructed. Theoretically infinite possibilities of the initial parameters as the key ensure the security of the proposed hash function against the unforgery and collision resistance. Finally, we establish a generic quantum walk-based hash function model and give a guide in constructing hash functions in quantum walk architecture. It also provides a clue for the construction of other quantum walk-based cryptography protocols.
Mechanism of terahertz (THz) pulse generation in gases irradiated by ultrashort laser pulses is investigated theoretically. Quasi-static transverse currents produced by laser field ionization of gases and the longitudinal modulation in formed plasmas are responsible for the THz emission at the electron plasma frequency, as demonstrated by particle-in-cell simulations including field ionization. The THz field amplitude scaling with the laser amplitude within a large range is also discussed. 相似文献
It is unavoidable to deal with the quark and gluon momentum and angular momentum contributions to the nucleon momentum and spin in the study of nucleon internal structure. However we never have the quark and gluon momentum, orbital angular momentum and gluon spin operators which satisfy both the gauge invariance and the canonical momentum and angular momentum commutation relation. The conflicts between the gauge invariance and canonical quantization requirement of these operators are discussed. A new set of quark and gluon momentum, orbital angular momentum and spin operators, which satisfy both the gauge invariance and canonical momentum and angular momentum commutation relation, are proposed. The key point to achieve such a proper decomposition is to separate the gauge field into the pure gauge and the gauge covariant parts. The same conflicts also exist in QED and quantum mechanics and have been solved in the same manner. The impacts of this new decomposition to the nucleon internal structure are discussed. 相似文献
Due to X-ray attenuation being approximately proportional to material density,it is possible to measure the inner density through Industrial Computed Tomography(ICT) images accurately. In practice,however,a number of factors including the non-linear effects of beam hardening and diffuse scattered radiation complicate the quantitative measurement of density variations in materials. This paper is based on the linearization method of beam hardening correction,and uses polynomial fitting coecient which is obtained by the curvature of iron polychromatic beam data to fit other materials. Through theoretical deduction,the paper proves that the density measure error is less than 2% if using pre-filters to make the spectrum of linear accelerator range mainly 0.3 MeV to 3 MeV. Experiment had been set up at an ICT system with a 9 MeV electron linear accelerator. The result is satisfactory. This technique makes the beam hardening correction easy and simple,and it is valuable for measuring the ICT density and making use of the CT images to recognize materials. 相似文献
We derive a model-independent integral formula for chiral susceptibility and attempt to present a continuum model study of it within the framework of Dyson–Schwinger equations. An appropriate regularization is implemented to remove the temperature-independent quadratic divergence inherent in this quantity. While it demonstrates a second-order phase transition characteristic in the chiral limit, the result obtained supports a crossover at physical current quark masses, which is in good agreement with recent lattice studies. 相似文献