Chromatic-distortion compensation in splitting and focusing of femtosecond pulses by use of a pair of diffractive optical elements

We propose a simple optical system to compensate for chromatic distortion that occurs during fan-out of femtosecond pulses by diffractive optics. The proposed system comprises a pair of diffractive elements, one for splitting an incoming pulse and the other for focusing the split pulses. With an appropriate separation between the elements, chromatic distortion resulting from the spectral bandwidth of a femtosecond pulse is removed, and an array of focused pulses with the same dimensions can be obtained. The theory has been verified through optical and processing experiments with 100-fs, 800-nm pulses.     

TETRAMETHOPRIM and PENTAMETHOPRIM: Synthesis,Antibacterial Properties and X-Ray Structures

TETRAMETHOPRIM ( 9 ) and PENTAMETHOPRIM ( 10 ), both prepared from the corresponding benzaldehydes 3 and 6 by conventional procedures, did not exhibit noteworthy antibacterial activity in vitro. A single crystal X-ray analysis of 9 and 10 provided evidence that the out-of-plane methoxy groups in the two compounds created a completely different topographical situation to that present in TRIMETHOPRIM , and less ideal for the binding to bacterial dihydrofolate reductase.     

Widely useful DMAP-catalyzed esterification under auxiliary base- and solvent-free conditions

With regard to atom economy and E-factor, catalytic condensation of carboxylic acids with equimolar amounts of alcohols is the most desirable. Although several highly active dehydration catalysts have been reported, more efficient alternatives are still strongly needed because the dehydrative esterification of tertiary alcohols, phenols, acid-sensitive alcohols, amino acids, and hardly soluble alcohols has never proceeded satisfactorily. Here we report new insights into the classical DMAP-catalyzed acylation of alcohols: surprisingly, only a 0.05-2 mol % of DMAP can efficiently promote acylation of alcohols with acid anhydrides under auxiliary base- and solvent-free conditions to give the corresponding esters in high yields. Furthermore, we achieved the recovery and reuse of commercially available polystyrene-supported DMAP without using any solvents. These serendipitous findings provide widely useful and environmentally benign esterification methods, which might be more practical and reliable than catalytic dehydrative condensation methods, in particular, for the less reactive alcohols which hardly condense with carboxylic acid directly.     

Small‐angle X‐ray scattering from poly(methylmethacrylate) in aqueous solutions of t‐butyl alcohol

Segment‐segment interaction of poly(methylmethacrylate) in t‐butyl alcohol‐water mixtures in poor solvent regime was studied. From the small‐angle X‐ray scattering measurements of semidilute solution range, the binary and ternary cluster integrals of polymer segments were determined from concentration dependence of the correlation length at various temperatures just above the upper critical solution temperature. We have calculated the contributions of the segment–segment interaction to the entropy and enthalpy from the measured temperature dependence of these interaction parameters and found that both quantities are negative and decrease with decreasing t‐butyl alcohol content. FT‐IR absorption peak of carbonyl group of poly(methylmethacrylate) shifts to the lower frequency with increasing water content. The implications of these findings are discussed. © 1999 John Wiley & Sons, Inc. J Polym Sci B: Polym Phys 37: 2195–2199, 1999     

Application to classification of mulberry leaves using multivariate analysis of proton NMR metabolomic data

Recently, NMR-based metabolomic analysis has been used to acquire information based on differentiation among biological samples. In the present study, we examined whether multivariate analysis was able to be applied to natural products and/or material field. Each extraction of 24 leaf samples, divided into six locations from the tip of the stem in each of four strains, was analyzed by pattern recognition methods, known as Principal Component Analysis (PCA) and Soft Independent Modeling of Class Analogy (SIMCA). Twenty-four extracts from mulberry leaf showed independent spectra by 1H NMR. The separation of leaf extraction data due to the difference at six locations was achieved in the PCA score plot as correlation PC1 (86.1%) and PC3 (4.6%) and showed two loading plots, suggesting classification by leaf position as an independent variable in the loading plot. Moreover, the difference among six locations clarified the seven highest discrimination powers by the SIMCA method. Meanwhile, the PCA score plot obtained classification by the variety of mulberry strains with three loading plots, but the SIMCA method did not give a peak by classification.     

Upper limit on gravitational wave backgrounds at 0.2 Hz with a torsion-bar antenna

We present the first upper limit on gravitational wave (GW) backgrounds at an unexplored frequency of 0.2 Hz using a torsion-bar antenna (TOBA). A TOBA was proposed to search for low-frequency GWs. We have developed a small-scaled TOBA and successfully found Ω(gw)(f)<4.3×10(17) at 0.2 Hz as demonstration of the TOBA's capabilities, where Ω(gw)(f) is the GW energy density per logarithmic frequency interval in units of the closure density. Our result is the first nonintegrated limit to bridge the gap between the LIGO band (around 100 Hz) and the Cassini band (10(-6)-10(-4) Hz).