Complex 69mZnLigCl2 (Lig is N-(5,6-dihydro-4H-1,3-thiazin-2-yl)benzamide) as a potential radiopharmaceutical

Russian Chemical Bulletin - The cytotoxicity of complex 69mZnLigCl2 (Lig is N-(5,6-dihydro-4H-1,3-thiazin-2-yl) benzamide) against the K-562 cell line (chronic myeloid leukemia) was considered in...     

Measurement of the Rate Constant of a Reaction of Chlorine Atoms with CH<Subscript>3</Subscript>Br in a Temperature Range of 298–358 K Using the Resonance Fluorescence of Chlorine Atoms

The rate constant of the reaction of chlorine atoms with CH₃Br was measured in a temperature range of 298–358 K using the resonance fluorescence of chlorine atoms. The possible role of this reaction in atmospheric chemistry and fire extinguishing was discussed. It was found that this reaction is homogeneous in contrast to the previously studied reaction of chlorine atoms with CH₃I, with occurs at the reactor surface.     

Multiplicities in84Kr interactions in emulsion at 800–950 MeV/nucleon

Inelastic interactions induced by⁸⁴Kr nuclei at 800–950 MeV/nucleon have been studied using a high angular resolution emulsion detector. Data on multiplicities of the produced particles, projectile and target fragments are shown. Comparisons with cascade calculations have been performed.We thank to Swedish Research Council for Natural Sciences for the financial support. Scanning and measurements performed by E.G. Broomé and V. Kopljar are acknowledged.     

Heterocyclic Ions From N-Oxides of N-(4-Nitrobenzylidene)-2-cyclopropylaniline and N-(4-Nitrobenzylidene)-2-cyclopropylmethylniline: Formation, Isomerization, and Conversions

The N-oxide of N-(4-nitrobenzylidene)-2-cyclopropylaniline is converted by the action of strong acids into the corresponding 2,1-benzoxazinium derivative. Under identical conditions the N-oxide of N-(4-nitrobenzylidene)-2-cyclopropylmethylaniline forms the corresponding 2,1-benzoxazinium and 2,1-benzoxazepinium salts in a ratio of 1 : 2. The 2,1-benzoxazepinium ions are thermodynamically less stable and are isomerized with time into 2,1-benzoxazinium ions. Treatment of 2,1-benzoxazinium salts with hydrobromic acid solution and subsequent neutralization leads to o-(2-hydroxyalkyl)anilines and p-nitrobenzaldehyde. The effect of the nature of the ortho substituent on the direction of the conversions of the corresponding arylcyclopropanes is discussed.     

N-Silatranylmethyl Derivatives of Pyrrole,Indole, and Carbazole

Organosilicon derivatives of pyrrole, indole, carbazole, and 2-methylindole containing (MeO)₃SiCH₂, Et₃SiCH₂, or N(CH₂CH₂O)₃SiCH₂ group on the nitrogen atom were synthesized. Their structure and stereoelectronic parameters were studied by X-ray diffraction, ¹H, ^{1 3}C, ^{1 5}N, and ^{2 9}Si NMR, IR and UV spectroscopy, and dielcometry, as well as by quantum-chemical calculations.     

Nitro azines. 21. Reactivities and electron structures of 6-nitroazolo[1,5-a]pyrimidines

6-Nitroazolopyrimidines react with the acetonyl anion to give 6-nitro-7-acetonyl-4,7-dihydroazolo[1,5-a]pyrimidines. The reactivity of this class of compounds with respect to charged and uncharged nucleophiles is determined by their aromatic character and the deficit of electron density in the pyrimidine ring, while the direction of attack is determined by the overall charge on fragments of the valence-bonded atoms.For Communication 20 see [1].Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 807–813, June, 1993.     

Triterpene saponins fromThalictrum minus. VIII. Structure of thalicoside D

Thalicoside D — a new triterpene glycoside isolated fromThalictrum minus L. (Ranunculaceae) — has the structure of oleanolic acid 3-O-[O-α-L-rhamnopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→4)-α-L-arabinopyranoside 28-O-[O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside]. This structure was established by the use of the results of acid and alkaline hydrolyses, SIMS spectra, and one- and two-dimensional NMR spectroscopy. Deceased.     

Preparation and properties of secondary amides of 1,1-dinitroalkanecarboxylic acids

The previously unknown secondary amides of 1,1-dinitroalkanecarboxylic acids were prepared by the reaction of polynitroimidoyl fluorides with water in the presence of mineral acids. They are inert with respect to electrophiles, but react with nucleophiles with the cleavage of the C-C bond between the carbonyl C atom and the C atom of the dinitromethylene group. An X-ray structural study of the amides was carried out and their thermochemical characteristics were determined.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 877–881, May, 1994.     

New reaction of the sodium salt of 2-nitroethanol. X-ray analysis of the sodium salt of 2-oxo-3-hydroxypropionic acid oxime, 2-bromo-2-nitropropane-1,3-diol,and the model 2,2-dinitropropane-1,3-diol

A novel reaction of the sodium salt of 2-nitroethanol in aqueous ammonia resulted in the sodium salt of 2-oxo-3-hydroxypropionic acid oxime (1) has been found. Bromination of1 affords 2-bromo-2-nitropropane-1,3-diol (2) with a previously unknown molecular conformation. The formation mechanisms of compounds1 and2 were suggested. X-ray analysis of products1,2 and that of the model compound, 2,2-dinitropropane-1,3-diol, was performed.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 1217–1221, May, 1996.     

On the Possibility of Flow Curve Analysis of Structured Disperse Systems Using the Catastrophe Theory

The possibility of analyzing the processes of the formation and destruction of disperse structures under dynamic conditions was considered using concepts of synergetics and the catastrophe theory. Such an approach is demonstrated by the results of studying phenomena typical of the shear flow of structured dispersions.