Superdeformation in142Eu

A rotational band with 15 transitions has been observed in¹⁴²Eu in an experiment with the GASP Ge detector array by the¹¹⁰Pd(³⁷Cl,5_n) reaction. The average energy spacing between the neighbouring transitions is 60 keV, which is similar to the energy spacings in the superdeformed bands in the mass 140 region. The band has a constant dynamic moment of inertia as suggested by Cranked Shell Model calculations.     

Analysis of human pituitary growth hormone and its charge variants by fast-atom bombardment mass spectrometry.

There is evidence that even highly purified preparations of human growth hormone are not homogenous, but contain charge as well as size variants. The charge heterogeneity was suggested to be due to deamidation of the native hormone. To verify this we have applied peptide mapping followed by fast-atom bombardment mass spectrometry (FAB-MS), in order to identify fragments containing the altered amino acids. Growth hormone was purified from human pituitaries and the differently charged forms were separated by column electrophoresis in agarose suspension. The isolated components were treated with trypsin and analysed directly by FAB-MS without prior separation by reversed-phase high-performance liquid chromatography (RP-HPLC). Using this technique, approximately 80% of the hormone structure was recovered and two deamidation sites were found in the fragment T15 (FDTNSHNDDALLK). The results clearly elucidated the potential use of FAB-MS for the fast screening of other variants of the growth hormone which are known to exist.     

Spectroscopy of neutron deficient 65Ge

Excited states of ⁶⁵Ge were populated via the ¹²C + ⁵⁸Ni (261 MeV) reaction using the NORDBALL detector array equipped with charged-particle and neutron detector systems for reaction channel separation. On the basis of γγ-coincidence relations and angular distribution ratios a significantly extended level scheme was constructed up to E _x = 9 MeV and J ^π = (33/2^?). The low-energy states of the nucleus are discussed in the framework of the interacting boson-fermion model.     

Quantitative Structure-Affinity Relationships of Dopamine D2 Receptor Antagonists: A Comparison between Orthopramides and 6-Methoxysalicylamides

A large series of orthopramides (= 2-methoxybenzamides), 6-methoxysalicylamides, and 2,6-dimethoxy-benzamides were examined for their affinity to the dopamine D₂ receptor. The binding data were correlated with physicochemical parameters and ¹³C-NMR chemical shifts using the cross-validated partial least-squares method and multiple linear regression analysis. The results quantitate the influence of electronic factors and lipophilicity to D₂ receptor binding. They also show that the N-[(1-ethylpyrroIidin-2-yl)methyl] and N-(1-benzylpiperidin-4-yl) side-chains affect the mode of binding of these compounds.     

<Emphasis Type="Italic">Gluconobacter</Emphasis> sp. cells for manufacturing of effective electrochemical biosensors and biofuel cells

Gluconobacter oxydans bacteria exhibit a unique metabolism for quick and incomplete oxidation of a wide range of different compounds (aldoses, ketoses, mono- and poly-alcohols, etc.). Such biotransformation efficiency with simple biomass production led to the industrial applications of these bacteria in the production of several important commodities. Their respiratory activity can also be successfully studied and used in the field of bioelectrochemistry. The main aim of this review is to present various strategies to improve selectivity of assays using intact/treated cells of G. oxydans, to introduce the application of G. oxydans-based biosensors in selective monitoring of analytes during biotransformation processes and to provide information about utilizable sugars in fermentation media or in biological oxygen demand value determination. The final part of the review describes potential application of G. oxydans cells in the generation of electricity from complex fuels within microbial fuel cells by advanced direct electron transfer route between bacterial cells and electrodes.     

Tight Heffter Arrays Exist for all Possible Values

A tight Heffter array is an matrix with nonzero entries from such that (i) the sum of the elements in each row and each column is 0, and (ii) no element from appears twice. We prove that exist if and only if both m and n are at least 3. If H has the property that all entries are integers of magnitude at most , every row and column sum is 0 over the integers, and H also satisfies ), we call H an integer Heffter array. We show integer Heffter arrays exist if and only if . Finally, an integer Heffter array is shiftable if each row and column contains the same number of positive and negative integers. We show that shiftable integer arrays exists exactly when both are even.     

Pressure-dependent viscosity of powder injection moulding compounds

A single piston capillary rheometer was modified by the addition of a second chamber with a restricting valve (developed at the Polymer Centre, Zlín, Czech Republic), which provides backpressure and increasing the pressure in the melted material during the flow through the die. The Carreau–Yasuda model was employed to fit the measured viscosity data and determine the temperature and pressure coefficients for polyolefin based binder and its compounds with carbide powder. Both temperature and pressure sensitivity coefficients are largely dependent on the structure of a polymer, which should be taken into account for binder-formation’s development. Increasing the loading level of the powder in the compound diminishes the pressure sensitivity of their flow properties.     

1,2-diphosphaacenaphthene 1,2-dications: synthetic, stereochemical and computational study of the stabilising role of naphthalene-1,8-diyl backbone

Syntheses and full characterisation data (including single crystal diffraction) of three 1,2‐diphosphonium dicationic species with the naphthalene‐1,8‐diyl (Nap) backbone are reported. The oxidation of Nap[P(NMe₂)₂]₂ with P₂I₄ to its 1,2‐dication was achieved. meso‐ and rac‐forms of “all carbon” 1,2‐diphosphonium dications were obtained in good yields and purity by double alkylation of the parent diphosphine (1,2‐diphenyl‐1,2‐diphosphaacenaphthene) with methyl triflate or trimethyloxonium tetrafluoroborate. Each methylating reagent produces one of the rac‐ or meso‐forms of the dication diastereospecifically. Structural parameters of the new dications are discussed with respect to other phosphorus 1,2‐dications. DFT (B3LYP) computations revealed the significant role of the naphthalene backbone in stabilisation of the dicationic motif and helped to assess the energy cost of the steric clash of a variety of groups attached to the peri‐positions of naphthalene. The synthesis and single crystal X‐ray data of the extremely crowded Nap[P(?Se)(OiPr)₂]₂ are discussed, and are contrasted with the unsuccessful synthesis of Nap(PtBu₂)₂ from NapLi₂ and ClPtBu₂.