The synthesis of possible hydroxylated metabolites of 2-chlorophenothiazine derivatives

The synthesis of 7-hydroxy, 8-hydroxy and 7,8-dihydroxy prochlorperazines (3a) and per-phenazines (3b) is reported. The parent ehlorophenothiazines were prepared analogously to previously reported chlorpromazine (3e) metabolite syntheses. The prochlorperazine side chain was introduced in one step using 1-(3-chloropropyl)-4-methylpiperazine and the perphenazine side chain in two steps, first reaction with 1-bromo-3-chloropropane followed by reaction with 1-piperazineethanol. The methoxymethyleneoxy O-proteetive groups were removed under mild conditions using methanolic hydrogen chloride. The preparations of 7-hydroxydesmethylprochlorperazine and 7-hydroxychlorpromazine quaternary methyl iodide are also reported.     

Thermal evidences for successive CDW phase transitions in 1T-TaS2

The heat capacity of 1T-TaS₂ has been measured over the temperature range including the successive phase transitions (140 K–370 K) by an adiabatic calorimeter. There are three transitions in the measured temperature range, two first-order transitions (at about 226 K (T₁) and about 353.5 K (T₃)) and one small anomaly at about 283 K (T₂) with a broad peak. The transition enthalpies are as follows; ΔH₁=52±5 cal·mol^-1, ΔH₂=7.5±2 cal· mol^-1 and ΔH₃=122±8cal·mol^-1.     

Untersuchungen über Hydratation von Metallhalidrauchen mit Elektronenbeugung

Zusammenfassung Mittels Elektronenbeugung wurden Versuche durchgeführt, die Hydratationsf?higkeit einiger Metallhalide festzustellen. Bei den Cd-Haliden nimmt die Hydratationsf?higkeit nach folgender Reihe ab: CdCl₂>CdBr₂>CdJ₂ und bei Metallchloriden nach folgender Reihe ZnCl₂>CdCl₂>PbCl₂>HgCl₂>Hg₂Cl₂ ab. Diese Ergebnisse entsprechen dem Anionen- oder Kationendurchmesser. Für 80% rel. Feuchtigkeit zeigen Hg₂Cl₂ und PbCl₂ Platzwechsel der Atome.     

Conformation of linear polyethylene in 1-chloronaphthalene: Light scattering characterization of polymers. IV

Light scattering measurements were carried out on a linear polyethylene sample NBS 1475 in 1-chloronaphthalene at 135 and 115°C to determine the weight-average molecular weight, the second virial coefficient A₂, and the z-average mean-square radius of gyration. By use of these results, the system is analyzed in terms of the interpenetration function Ψ for A₂. Observed values of A₂ are rather large but the excluded volume is nevertheless relatively small. Such behavior seem to be similar to that of semiflexible polymers. The characteristic ratio C_n,LS as determined by light scattering is found to be almost twice the literature value of 6.7, which was obtained from viscosity measurements. This discrepancy is explained by comparing the theoretical value of the Flory viscosity parameter Φ at the nondraining limit with values calculated from the light scattering results.     

High-resolution optogalvanic study of the c4(0)1Πu, c′5(0)1Σu+, and a″(0)1Σg+ Rydberg states of N2

A new optogalvanic technique with an rf discharge was applied to a high-resolution study of the Rydberg states of N₂. The Ledbetter band, c₄(0)¹Π_u ← a″(0)¹Σ_g⁺, and a new visible band, c′₅(0)¹Σ_u⁺ ← a″(0)¹Σ_g⁺, were studied at a Doppler-limited resolution of 0.05 cm^?1. A Doppler-free method was also applied to resolve overlapped lines. Precise wavenumbers were determined for the rotational transitions of the two Rydberg bands. The rotational and the centrifugal constants for the lowest Rydberg state, a″(0)¹Σ_g⁺, were determined to be B₀ = 1.913748(42) cm^?1 and D₀ = 6.088(99) × 10^?6 cm^?1, where the numbers in parentheses are the standard deviation and apply to the last digits.     

Molecular structure of biphenyl in an argon matrix

The infrared spectrum of biphenyl was measured in an Ar matrix at 20 K. A comparison of the results with the spectra of this molecule in the solid liquid states shows that the structure of biphenyl in the matrix is similar to that in the liquid state, that is, the molecule is non-planar.     

Fluctuation in superradiance

The fluctuation of the intensity of superradiant pulse is calculated by applying a general asymptotic evaluation method of quantal macrovariables to a superradiant master equation. It is shown that the fluctuation of superradiant intensity is proportional to the cube of the number of the relevant atoms. The time-dependence of the proportional coefficient has been evaluated explicitly. It is predicted that there occurs an enhancement of fluctuation of superradiant intensity at an intermediate time. The intensity and fluctuation of higher order are also calculated. General expressions of expansion coefficients of a generating function are also given rigorously.