We devised a new method of data mining for a large-scale database. In the method, a network of locally coupled phase oscillators subject to Kuramoto's model substitutes for given multivariate data to generate major features through phase locking of the oscillators, i.e., phase transition of the data set. We applied the method to the national database of care needs certification for the Japanese public long-term care insurance program, and found three major patterns in the aging process of the frail elderly. This work revealed the latent utility of Kuramoto's model for data processing. 相似文献
[structure: see text]. A novel method for the preparation of hydroxy carboxylic acid derivatives has been developed by O2-oxidation of pi-allylnickel intermediates generated by Ni(0)-mediated coupling of 1,2-dienes with CO2. 相似文献
The gas sorption capacities of sputtered carbonaceous films are evaluated with quartz crystal resonators. These films are
sensitive to 20 ppm organic vapors and exhibit structure-dependent responses. Films derived from synthetic polymers are hydrophobic,
whereas films derived from biomaterials are amphiphilic or hydrophilic. Polyethylene (PE) film has an extremely high sorption
capacity for a wide range of vapors. Transient sorption responses are investigated using a humidified carrier by employing
carboxylic acid esters, whose aliphatic groups are systematically changed. Small esters with a higher affinity to water induce negative U-shaped responses from amphiphilic films derived from biomaterials.
On the other hand, polymeric films exhibit positive exponential response curves. Even if the concentrations are decreased,
the response intensities are enhanced with the incremental expansion of carbon chains of aliphatic groups. Only fluoropolymer
film shows the opposite tendency. The modeling of quantitative structure property relationships has indicated that the sorption
capacities of the PE film to the carboxylic acid esters are fundamentally governed by electrostatic interactions. The intermolecular
attractive forces are basically attributable to interactions between the positively polarized sites in esters and the negatively
polarized/charged sites in PE film. 相似文献
We developed intramolecular dual fluorophore-quencher base analogues for site-specific incorporation into DNA by an unnatural base pair replication system. An unnatural base pair between 7-(2-thienyl)-imidazo[4,5-b]pyridine (Ds) and 2-nitro-4-propynylpyrrole (Px) exhibits high fidelity in PCR amplification, and the 2-nitropyrrole moiety of Px acts as a quencher. Deoxyribonucleoside triphosphates of Px linked with a fluorophore (Cy3, Cy5 or FAM) were chemically synthesized, and the fluorescent properties and the enzymatic incorporation of the fluorophore-linked dPxTPs into DNA were examined in PCR amplification. The fluorophore-linked dPxTPs were site-specifically incorporated by PCR into DNA, opposite Ds in templates, with high selectivity. Furthermore, we found that the fluorescence of the triphosphates was partially quenched, but increased upon their incorporation into DNA. These dual fluorophore-quencher base analogues would be useful for site-specific DNA labeling and for monitoring the amplification products of target nucleic acid molecules with a specific sequence. We have demonstrated the utility of the fluorophore-linked Px substrates and the Ds-Px pairing in real-time quantitative PCR for target DNA molecule detection. 相似文献
N-fused carbazole-zinc porphyrin-free-base porphyrin triad featuring an ethynyl-linkage was synthesized; efficient sensitization as long as 900 nm was demonstrated and an overall light-to-electricity conversion efficiency of 5.21% was achieved under AM 1.5 G one sun illumination. 相似文献
A 3,6-bis(5-amino-2-pyridyl)-1,2,4,5-tetrazine exhibits strong π-π* fluoresce in the presence of zinc ion (Zn(2+)) in aqueous solution, whereas it is not fluorescent in the absence of Zn(2+) as well as in the presence of competing metal ions. 相似文献
A new type of Pt-complex-bound amino acid was synthesized by condensation of a cyclometalated Pt complex with the side-chain residue of N- and C-alkylated glutamic acid. Self-assembly of the Pt-bound lipophilic amino acid afforded a supramolecular gel in organic solvents, which comprised fibrous lamellar aggregates that supported a highly oriented Pt array. 相似文献
We synthesized new bidentate N-heterocyclic carbene Ag and Rh complexes with xanthene skeleton. The structural of the complexes were analyzed by NMR spectroscopy and X-ray crystallography. The complexes adopted cis or trans configuration, depending on the structure of the ligand. 相似文献
Hydrogels were successfully synthesized utilizing CO2 as a gellant. A cross‐linking reaction of polyallylamine (PAA) with CO2 in the presence of 1,8‐Diazabicyclo[5,4,0]‐undec‐7‐ene (DBU) provided hydrogels bearing urea cross‐linking points and residual amino groups in the side chains. The obtained hydrogels absorbed CO2 at 25 °C and gave a maximum absorption four times larger than that of PAA aqueous solution and 2.8 times larger than that of the most commonly used absorbent, monoethanolamine. The PAA hydrogels desorbed the absorbed CO2 completely under a N2 atmosphere at 120 °C, and could be repeatedly recycled without loss of efficiency, indicating their potential application as recyclable CO2 absorption materials.